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Cablinosides A and B, Two Glycosidic Phenylacetic Acid Derivatives from the Leaves of Pogostemon cablin
Huang, XJ1,2; Li, P1; Yin, ZQ3; Lu, JJ1; Lin, LG1; Wang, Y2; Ye, WC2; Zhang, QW1
2019
Source PublicationCHEMISTRY & BIODIVERSITY
ISSN1612-1872
Volume16Issue:5
Abstract

A pair of new glycosidic epimers, cablinosides A (1a) and B (1b) were isolated from the leaves of Pogostemon cablin. The structures with absolute configurations of 1a and 1b were elucidated by extensive NMR investigation, and quantum chemical CD calculations. The epimer mixture 1 showed moderate α‐glucosidase inhibitory activity and no significant cytotoxic activity against HepG2 cells.

KeywordPhytochemistry Pogostemon Cablin Cablinosides a And b Patchouli Cytotoxicity Inhibitors Structure Elucidation
DOI10.1002/cbdv.201900137
Indexed BySCI
Language英语
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry
WOS SubjectBiochemistry & Molecular Biology ; Chemistry, Multidisciplinary
WOS IDWOS:000476956200023
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Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorYin, ZQ
Affiliation1.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, P. R. China
2.Institute of Traditional Chinese Medicine and Natural Products & Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research, Jinan University, Guangzhou, 510632 P. R. China
3.Department of TCMs Pharmaceuticals, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 210009 P.R. China
First Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Huang, XJ,Li, P,Yin, ZQ,et al. Cablinosides A and B, Two Glycosidic Phenylacetic Acid Derivatives from the Leaves of Pogostemon cablin[J]. CHEMISTRY & BIODIVERSITY,2019,16(5).
APA Huang, XJ.,Li, P.,Yin, ZQ.,Lu, JJ.,Lin, LG.,...&Zhang, QW.(2019).Cablinosides A and B, Two Glycosidic Phenylacetic Acid Derivatives from the Leaves of Pogostemon cablin.CHEMISTRY & BIODIVERSITY,16(5).
MLA Huang, XJ,et al."Cablinosides A and B, Two Glycosidic Phenylacetic Acid Derivatives from the Leaves of Pogostemon cablin".CHEMISTRY & BIODIVERSITY 16.5(2019).
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