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Rapid detection of aflatoxin B-1 by dummy template molecularly imprinted polymer capped CdTe quantum dots
Pengqi Guo1,2; Wu Yang1; Hao Hu1; Yitao Wang1; Peng Li1
2019-05
Source PublicationAnalytical and Bioanalytical Chemistry
ISSN1618-2642
Volume411Issue:12Pages:2607-2617
Abstract

A novel and sensitive fluorescent sensor was synthesized for the rapid and specific recognition of aflatoxin B1 (AFB1) by our combining molecular imprinting techniques with quantum dot technology. Molecularly imprinted polymers coated CdTe quantum dots (MIP@CdTe QDs) were prepared through the Stöber method with 5,7-dimethoxycoumarin as a dummy template. 3-Aminopropyltriethoxysilane was selected as the functional monomer, and tetraethyl orthosilicate was used as the cross-linking agent. The best molar ratio of 5,7-dimethoxycoumarin to functional monomer to cross-linker was 4:20:15. The MIP@CdTe QD composites were characterized by Fourier transform infrared spectroscopy, transmission electron microscopy, and fluorescence spectroscopy. Under the optimum conditions, the relative fluorescence intensity of the MIP@CdTe QDs showed adequate linearity with AFB1 concentration over the range from 80 to 400 ng/g. The detection limit is 4 ng/g, according to 3s/K. Finally, the method was successfully applied to the quantitative determination of AFB1 in real samples. The spike recoveries at different spiking levels ranged from 99.20% to 101.78%, which were consistent with those measured by ultrahigh-performance liquid chromatography–mass spectrometry. The method developed for AFB1 detection lays the foundation for rapid detection of trace amounts of other exogenous harmful substances in a complicated matrix.

KeywordCdte Quantum Dots Dummy Template Molecularly Imprinted Polymers Aflatoxin B1 Fluorescent Probe
DOIhttps://doi.org/10.1007/s00216-019-01708-2
Indexed BySCI
Language英语
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry
WOS SubjectBiochemical Research Methods ; Chemistry, Analytical
WOS IDWOS:000464948100015
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Cited Times [WOS]:5   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorPeng Li
Affiliation1.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau, China
2.School of Chemical Engineering, Northwest University, Xi’an, China
First Author AffilicationInstitute of Chinese Medical Sciences
Corresponding Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Pengqi Guo,Wu Yang,Hao Hu,et al. Rapid detection of aflatoxin B-1 by dummy template molecularly imprinted polymer capped CdTe quantum dots[J]. Analytical and Bioanalytical Chemistry,2019,411(12):2607-2617.
APA Pengqi Guo,Wu Yang,Hao Hu,Yitao Wang,&Peng Li.(2019).Rapid detection of aflatoxin B-1 by dummy template molecularly imprinted polymer capped CdTe quantum dots.Analytical and Bioanalytical Chemistry,411(12),2607-2617.
MLA Pengqi Guo,et al."Rapid detection of aflatoxin B-1 by dummy template molecularly imprinted polymer capped CdTe quantum dots".Analytical and Bioanalytical Chemistry 411.12(2019):2607-2617.
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