UM  > 中華醫藥研究院
Natural Deep Eutectic Solvents for Simultaneous Extraction of Multi-Bioactive Components from Jinqi Jiangtang Preparations
Lele Yang1; Ling Li2; Hao Hu1; Jianbo Wan1; Peng Li1
2019-01
Source PublicationPHARMACEUTICS
ISSN1999-4923
Volume11Issue:1
Abstract

Natural deep eutectic solvents (NADESs), composed of natural primary metabolites, are now widely used as green and sustainable extraction solvents of bioactive components. In the present study, various NADESs were prepared to extract multi-components from different preparations of an herbal formula (Chinese name: Jinqi Jiangtang, JQJT) using ultrasound-assisted extraction (UAE). Results showed that most prepared NADESs provided more effective extraction of phenolic acids and alkaloids from JQJT preparations than conventional solvents. Among the tested NADESs, the solvent formed by choline chloride and laevulinic acid was selected to optimize the operational parameters using response surface methodology. The optimized extraction method was successfully applied to extract six major components in four commercial JQJT products, and quantification analysis was performed by the validated high-performance liquid chromatography with ultraviolet detection (HPLC-UV) method. The quantitative results indicated that preparations from different manufacturers showed different chemical profiles. In conclusion, NADESs-based UAE shows considerable potential as an efficient and green method for extraction of multi-bioactive components from commercial herbal preparations.

KeywordDeep Eutectic Solvents Jinqi Jiangtang Ultrasound Assisted Extraction Esponse Surface Methodology Bioactive Components
DOI10.3390/pharmaceutics11010018
Indexed BySCI
Language英语
WOS Research AreaPharmacology & Pharmacy
WOS SubjectPharmacology & Pharmacy
WOS IDWOS:000459732200018
Fulltext Access
Citation statistics
Cited Times [WOS]:4   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Affiliation1.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences,University of Macau, Macau 999078, China;
2.Bioengineering College, Xihua University, Chengdu 610000, China
First Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Lele Yang,Ling Li,Hao Hu,et al. Natural Deep Eutectic Solvents for Simultaneous Extraction of Multi-Bioactive Components from Jinqi Jiangtang Preparations[J]. PHARMACEUTICS,2019,11(1).
APA Lele Yang,Ling Li,Hao Hu,Jianbo Wan,&Peng Li.(2019).Natural Deep Eutectic Solvents for Simultaneous Extraction of Multi-Bioactive Components from Jinqi Jiangtang Preparations.PHARMACEUTICS,11(1).
MLA Lele Yang,et al."Natural Deep Eutectic Solvents for Simultaneous Extraction of Multi-Bioactive Components from Jinqi Jiangtang Preparations".PHARMACEUTICS 11.1(2019).
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Lele Yang]'s Articles
[Ling Li]'s Articles
[Hao Hu]'s Articles
Baidu academic
Similar articles in Baidu academic
[Lele Yang]'s Articles
[Ling Li]'s Articles
[Hao Hu]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Lele Yang]'s Articles
[Ling Li]'s Articles
[Hao Hu]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.