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DIGITAL MICROFLUIDICS FOR POLYMERASE CHAIN REACTION
Yanwei JIA; Liang WAN; Cheng DONG; Haoran LI; Tianlan CHEN; Pui In MAK; Rui Paulo da Silva MARTINS
Rights HolderUNIVERSITY OF MACAU
Date Available2019-11-28
CountryUnited States
Subtype发明专利
Contribution Rank1
Abstract

Provided is a digital microfluidic device for quick polymerase chain reaction. The digital microfluidic device includes an enclosed chamber for holding droplets comprising PCR mixtures. The chamber has an upper layer and a lower layer, which provide a top heater and a bottom heater contained in a thermal electrode respectively to form dual heaters. The lower layer further has an array of electrodes and a dielectric layer, e.g. Norland Optical adhesive 61, coating thereon. Such arrangement of the digital microfluidic device allows quick and homogeneous heating of droplets to lower the heating voltage, shorten the reaction time, and prevent the dielectric layer from breakdown during the thermal cycle.

Application Date2019-05-20
Patent NumberUS20190358636A1
Language英语
Application NumberUS16416337
Open (Notice) NumberUS20190358636A1
Fulltext Access
Document TypePatent
CollectionINSTITUTE OF MICROELECTRONICS
DEPARTMENT OF ELECTRICAL AND COMPUTER ENGINEERING
AffiliationUniversity of Macau
First Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714
Yanwei JIA,Liang WAN,Cheng DONG,et al. DIGITAL MICROFLUIDICS FOR POLYMERASE CHAIN REACTION. US20190358636A1.
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