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Comparison of Different Attenuation Correction Methods for Dual Gating Myocardial Perfusion SPECT/CT
Qi Zhang; Duo Zhang; Greta S. P. Mok
2019-09
Source PublicationIEEE TRANSACTIONS ON RADIATION AND PLASMA MEDICAL SCIENCES
ISSN2469-7311
Volume3Issue:5Pages:565-571
Abstract

Dual respiratory-cardiac gating realizes motion-freeze myocardial perfusion single photon emission computed tomography (SPECT). The aim of this paper is to evaluate the performance of various attenuation maps for dual gating cardiac SPECT. We used extended cardiac-torso phantom with Tc-99m-sestamibi distribution to generate a dataset with both respiratory and cardiac motion and then grouped them based on six respiratory and eight cardiac phases. The corresponding attenuation correction (AC) maps were used to simulate different CT protocols: dual gating CT (DCT), respiratory gated CT (RCT), tine average CT (ACT), interpolated CT (ICT), helical CTs at end-inspiration (HCT-in), end-expiration (HCT-ex), and mid-respiration (HCT-mid), respectively. One hundred and twenty noise-free and realistic noisy projections were generated over 180 degrees from RAO to LPO and reconstructed by OS-EM method using different AC maps. The reconstructed images in different respiratory phases were registered to one reference endexpiration phase and summed up as a cardiac image for each cardiac phase. The corresponding polar maps were generated and further analyzed using 17-segment plots. Relative difference (RD) of the average intensity was computed in each segment using the polar maps with DCT-AC as reference. Substantial artifacts could be found in HCT-in AC images in every cardiac phase. For all eight noise-free cardiac phases, the average RD max for AC with ACT, HCT-ex, HCT-in, HCT-mid, RCT, and ICT comparing to DCT were 4.76%, 4.95%, 10.54%, 4.23%, 2.39%, and 2.76%, respectively. For all eight noisy cardiac phases, the average RD max for AC with ACT, HCT-ex, HCT-in, HCT-mid, RCT, and ICT comparing to DCT were 4.09%, 5.04%, 9.24%, 4.02%, 3.22%, and 2.85%, respectively. The ICT and RCT have the best AC performance for dual gating SPECT, while HCT-ex, HCT-in, HCT-mid, and ACT show inferior results. Since RCT and DCT are not commonly used in clinics due to complex implementation and radiation concern, ICT is recommended, followed by HCT-mid or HCT-ex for AC in dual gating cardiac SPECT with good accuracy and relative low radiation dose.

KeywordAttenuation Correction (Ac) Dual Gating Myocardial Perfusion Single Photon Emission Computed Tomography (Spect)/ct
DOI10.1109/TRPMS.2019.2899066
Language英语
WOS Research AreaRadiology, Nuclear Medicine & Medical Imaging
WOS SubjectRadiology, Nuclear Medicine & Medical Imaging
WOS IDWOS:000484301800005
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Cited Times [WOS]:0   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionDEPARTMENT OF ELECTRICAL AND COMPUTER ENGINEERING
Corresponding AuthorGreta S. P. Mok
AffiliationDepartment of Electrical and Computer Engineering, Faculty of Science and Technology, University of Macau, Macau, China
First Author AffilicationFaculty of Science and Technology
Corresponding Author AffilicationFaculty of Science and Technology
Recommended Citation
GB/T 7714
Qi Zhang,Duo Zhang,Greta S. P. Mok. Comparison of Different Attenuation Correction Methods for Dual Gating Myocardial Perfusion SPECT/CT[J]. IEEE TRANSACTIONS ON RADIATION AND PLASMA MEDICAL SCIENCES,2019,3(5):565-571.
APA Qi Zhang,Duo Zhang,&Greta S. P. Mok.(2019).Comparison of Different Attenuation Correction Methods for Dual Gating Myocardial Perfusion SPECT/CT.IEEE TRANSACTIONS ON RADIATION AND PLASMA MEDICAL SCIENCES,3(5),565-571.
MLA Qi Zhang,et al."Comparison of Different Attenuation Correction Methods for Dual Gating Myocardial Perfusion SPECT/CT".IEEE TRANSACTIONS ON RADIATION AND PLASMA MEDICAL SCIENCES 3.5(2019):565-571.
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