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Antioxidant and cytoprotective activities of an ancient Mediterranean citrus (Citrus lumia Risso) albedo extract: Microscopic observations and polyphenol characterization
Antonella Smeriglio1; Laura Cornara2; Marcella Denaro1; Davide Barreca1; Bruno Burlando3; Jianbo Xiao4; Domenico Trombetta1
2019-05-01
Conference Name3rd International Symposium on Phytochemicals in Medicine and Food (ISPMF)
Source PublicationFOOD CHEMISTRY
Volume279
Pages347-355
Conference DateAUG 25-30, 2018
Conference PlaceKunming, PEOPLES R CHINA
Abstract

Citrus fruits are a rich source of bio-functional compounds with various and well-proven health properties. We focused our attention on an ancient Mediterranean species, Citrus lumia Risso. The aim of this work was to investigate the polyphenol content and biological activities of C. lumia albedo extract by cell-free and cell-based assays. Fifteen polyphenols were quantified by LC-DAD-FLD analysis (flavonoids 89.34% and phenolic acids 10.66%) with eriocitrin and hesperidin as major components (52.81% and 31.31%, respectively). These results were corroborated also by micromorphological observations, which showed clusters of needle-shaped crystals of hesperidin highlighted by TBO staining. C. lumia albedo extract revealed marked antioxidant and free radical scavenging properties, and a significant cytoprotective activity on t-BOOH-treated lymphocytes. Results indicate that C. lumia albedo extract could be exploited as an antioxidant source, suggesting the use of albedo, currently considered a by-product, as a valuable raw material for nutraceutical employments.

KeywordCitrus Lumia Risso Flavonoids Hesperidin Crystals Antioxidant Properties Cytoprotective Activity Polyphenols Albedo Extract
DOIhttps://doi.org/10.1016/j.foodchem.2018.11.138
Indexed BySCIE ; CPCI
Language英语
WOS Research AreaChemistry ; Food Science & Technology ; Nutrition & Dietetics
WOS SubjectChemistry, Applied ; Food Science & Technology ; Nutrition & Dietetics
WOS IDWOS:000454689200042
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Cited Times [WOS]:14   [WOS Record]     [Related Records in WOS]
Document TypeConference paper
CollectionInstitute of Chinese Medical Sciences
Affiliation1.Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy
2.Department of Earth, Environment and Life Sciences, University of Genova, Italy
3.Department of Pharmacy, University of Genova, Italy
4.Institute of Chinese Medical Sciences, State Key Laboratory of Quality Research in Chinese Medicine, University of Macau, Taipa, Macau, China
Recommended Citation
GB/T 7714
Antonella Smeriglio,Laura Cornara,Marcella Denaro,et al. Antioxidant and cytoprotective activities of an ancient Mediterranean citrus (Citrus lumia Risso) albedo extract: Microscopic observations and polyphenol characterization[C],2019:347-355.
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