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1. Single-cell RNA-Seq reveals cell heterogeneity and hierarchy withi.. [46]
2. BRCA1 represses DNA replication initiation through antagonizing es.. [38]
3. Olfactomedin 4 deficiency promotes prostate neoplastic progression.. [32]
4. A novel FGFR1-binding peptide exhibits anti-tumor effect on lung c.. [29]
5. Postnatal deletion of Alk5 gene in meniscal cartilage accelerates .. [29]
6. BRCA1 function in the intra-S checkpoint is activated by acetylati.. [28]
7. Epigenetic targeting drugs potentiate chemotherapeutic effects in .. [28]
8. Inducible Activation of FGFR2 in Adult Mice Promotes Bone Formatio.. [26]
9. A novel FGFR1-binding peptide attenuates the degeneration ofarticu.. [26]
10. Optimizing CRISPR/Cas9 technology for precise correction of the Fg.. [25]
11. A digital microfluidic system for loop-mediated isothermal amplifi.. [24]
12. Cyclin B1 stability is increased by interaction with BRCA1, and it.. [23]
13. Bombesin-like receptor 3 (Brs3) expression in glutamatergic, but n.. [23]
14. Emerging roles of SIRT1 in fatty liver diseases [23]
15. Adeno-Associated Virus-Mediated RNAi against Mutant Alleles Attenu.. [23]
16. BRCA1 deficiency sensitizes breast cancer cells to bromodomain and.. [23]
17. A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations i.. [22]
18. A comprehensive genomic meta-analysis identifies confirmatory role.. [21]
19. Bombesin-like receptor 3 (Brs3) expression in glutamatergic, but n.. [20]
20. Drug screening of cancer cell lines and human primary tumors using.. [17]
21. Characterization of potential driver mutations involved in human b.. [17]
22. WEE1 inhibition targets cell cycle checkpoints for triple negative.. [17]
23. Partial müllerian duct retention in Smad4 conditional mutant male.. [17]
24. SIRT6 Is Essential for Adipocyte Differentiation by Regulating Mit.. [16]
25. Fibroblast Growth Factor Receptor 2 Signaling in Breast Cancer [14]
26. Alcohol, stem cells and cancer [14]
27. Potential therapeutic targets of triple-negative breast cancer bas.. [13]
28. Fibroblast Growth Factor Receptor 2 (FGFR2) Mutation Related Syndr.. [13]
29. Ammonium tetrathiomolybdate treatment targets the copper transport.. [13]
30. Conditional deletion of FOXL2 and SMAD4 in gonadotropes of adult m.. [12]
31. Analysis of Genomes and Transcriptomes of Hepatocellular Carcinoma.. [12]
32. Drug repurposing screen identifies lestaurtinib amplifies the abil.. [12]
33. Centrosome amplification and a defective G2-M cell cycle checkpoin.. [12]
34. Current Progresses of Exosomes as Cancer Diagnostic and Prognostic.. [12]
35. “DNA binding region“ of BRCA1 affects genetic stability through .. [11]
36. SIRT1 deacetylates TopBP1 and modulates intra-sphase checkpoint an.. [11]
37. Identification of an integrated SV40 T/t-antigen cancer signature .. [11]
38. Induction of intrahepatic cholangiocellular carcinoma by liver-spe.. [11]
39. Generation of Smurf2 conditional knockout mice [10]
40. Inhibition of Estrogen Signaling Reduces the Incidence of BRCA1-as.. [10]
41. Sexual Fate Change of XX Germ Cells Caused by the Deletion of SMAD.. [10]
42. Negative reciprocal regulation between Sirt1 and Per2 modulates th.. [10]
43. A role of SMAD4 in iron metabolism through the positive regulation.. [10]
44. A dual-specific IGF-I/II human engineered antibody domain inhibits.. [10]
45. SMAD3 Regulates follicle-stimulating hormone synthesis by pituitar.. [9]
46. Smad4 is required to inhibit osteoclastogenesis and maintain bone .. [9]
47. Silencing of unsynapsed meiotic chromosomes in the mouse [9]
48. Precision Medicine for Personalized Cancer Therapy [9]
49. Non-classical estrogen signaling in ovarian cancer improves chemo-.. [9]
50. CRISPR-Cas9: from Genome Editing to Cancer Research [8]
51. Fibroblast Grouth Factor Receptor (FGFR2) Mutation Related Symdrom.. [8]
52. The epigenetically downregulated factor CYGB suppresses breast can.. [8]
53. The role of TGF-β/SMAD4 signaling in cancer [7]
54. Inhibition of AKT suppresses the initiation and progression of BRC.. [7]
55. PRAJA is overexpressed in glioblastoma and contributes to neural p.. [7]
56. SIRT1 disruption in human fetal hepatocytes leads to increased acc.. [7]
57. A mechanism for 1,4-Benzoquinone-induced genotoxicity [7]
58. Tak1, Smad4 and Trim33 redundantly mediate TGF-β3 signaling durin.. [7]
59. Adapted resistance to the knockdown effect of shRNA-derived Srsf3 .. [6]
60. Hepatic-specific disruption of SIRT6 in mice results in fatty live.. [6]
61. PP2AC alpha deficiency impairs early cortical development through .. [6]
62. SIRT3 Deacetylates ATP Synthase F1 Complex Proteins in Response to.. [2]

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