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BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis Journal article
Advanced Science, 2020,Volume: 7,Issue: 6
Authors:  Chen,Qiang;  Lei,Josh Haipeng;  Bao,Jiaolin;  Wang,Haitao;  Hao,Wenhui;  Li,Licen;  Peng,Cheng;  Masuda,Takaaki;  Miao,Kai;  Xu,Jun;  Xu,Xiaoling;  Deng,Chu Xia
Favorite  |  View/Download:0/0  |  Submit date:2020/09/16
ATM-AMPK-DRP1  BRCA1  inflammasomes  mitochondrial dynamics  mitophagy  
Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 9,Page: 1193-1204
Authors:  Ting-ting Zhou;  Tong Zhao;  Fei Ma;  Yi-nan Zhang;  Jing Jiang;  Yuan Ruan;  Qiu-ying Yan;  Gai-hong Wang;  Jin Ren;  Xiao-wei Guan;  Jun Guo;  Yong-hua Zhao;  Ji-ming Ye;  Li-hong Hu;  Jing Chen;  Xu Shen
Favorite  |  View/Download:8/0  |  Submit date:2020/04/14
Type 2 Diabetes Mellitus  Hepatic Gluconeogenesis  Ampk Signaling Pathway  (e)-3-(2-(Quinoline-4-yl)Vinyl)-1h-indol-6-ol (Qvo)  4-[2-(1h-indol-3-yl)Vinyl]Quinoline (Ivq)  Prodrug  
Metformin protects PC12 cells and hippocampal neurons from H2O (2)-induced oxidative damage through activation of AMPK pathway Journal article
JOURNAL OF CELLULAR PHYSIOLOGY, 2019,Volume: 234,Issue: 9,Page: 16619-16629
Authors:  Xia Zhao;  Zhiwen Zeng;  Uma Gaur;  Jiankang Fang;  Tangming Peng;  Shuai Li;  Wenhua Zheng
Favorite  |  View/Download:8/0  |  Submit date:2020/06/11
Aging  Amp-activated Protein Kinase  Hydrogen Peroxide  Metformin  Pc12 Cells  
Elevated Exogenous Pyruvate Potentiates Mesodermal Differentiation through Metabolic Modulation and AMPK/mTOR Pathway in Human Embryonic Stem Cells Journal article
STEM CELL REPORTS, 2019,Volume: 13,Issue: 2,Page: 338-351
Authors:  Chengcheng Song;  Faxiang Xu;  Zhili Ren;  Yumeng Zhang;  Ya Meng;  Yiqi Yang;  Shreyas Lingadahalli;  Edwin Cheung;  Gang Li;  Weiwei Liu;  Jianbo Wan;  Yang Zhao;  Guokai Chen
Favorite  |  View/Download:15/0  |  Submit date:2020/04/22
Hescs  Pyruvate  Bmp4  Glycolysis  Tca Cycle  Ampk  Wnt  Metabolism  Mesoderm  Differentiation  
Phosphorylation of TET2 by AMPK is indispensable in myogenic differentiation Journal article
EPIGENETICS & CHROMATIN, 2019,Volume: 12
Authors:  Ting Zhang;  Xiaowen Guan;  Un Lam Choi;  Qiang Dong;  Melody M. T. Lam;  Jianming Zeng;  Jun Xiong;  Xianju Wang;  Terence C. W. Poon;  Hongjie Zhang;  Xuanjun Zhang;  Hailin Wang;  Ruiyu Xie;  Bing Zhu;  Gang Li
Favorite  |  View/Download:11/0  |  Submit date:2020/05/26
Ampk  Tet2  Phosphorylation  Myogenesis  Pax7  
A combination of Pueraria lobata and Silybum marianum protects against alcoholic liver disease in mice Journal article
PHYTOMEDICINE, 2019,Volume: 58
Authors:  Feng Ruibing;  Chen Jie-Hua;  Liu Cong-Hui;  Xia Fang-Bo;  Xiao Zeyu;  hang Xuguang;  Wan Jian-Bo
Favorite  |  View/Download:13/0  |  Submit date:2020/04/22
SiL.bum Marianum(L.)Gaerth  Pueraria Lobata(Wild.)Ohwi  Alcoholic Liver Disease  Hepatic Inflammation  Intestinal Barrier Dysfunction  
Upregulation of phosphoserine phosphatase contributes to tumor progression and predicts poor prognosis in non-small cell lung cancer patients Journal article
THORACIC CANCER, 2019,Volume: 10,Issue: 5,Page: 1203-1212
Authors:  Li Liao;  Huajian Yu;  Mengxi Ge;  Qiong Zhan;  Ruofan Huang;  Xiaoyu Ji;  Xiaohua Liang;  Xinli Zhou
Favorite  |  View/Download:10/0  |  Submit date:2020/03/10
Akt/ampk Signaling Pathway  Metastasis  Nsclc  Proliferation  Psph  
Myricanol mitigates lipid accumulation in 3T3-L1 adipocytes and high fat diet-fed zebrafish via activating AMP-activated protein kinase Journal article
Food Chemistry, 2019,Volume: 270,Page: 305-314
Authors:  Shen S.;  Liao Q.;  Feng Y.;  Liu J.;  Pan R.;  Lee S.M.-Y.;  Lin L.
Favorite  |  View/Download:20/0  |  Submit date:2018/11/06
Adipogenesis  Amp-activated Protein Kinase  Insulin Sensitivity  Lipid Accumulation  Myricanol  Zebrafish  
Triterpenoids from Cyclocarya paliurus that Enhance Glucose Uptake in 3T3-L1 Adipocytes Journal article
MOLECULES, 2019,Volume: 24,Issue: 1
Authors:  Zhu-Jun Fang;  Sheng-Nan Shen;  Jia-Min Wang;  Yong-Jiang Wu;  Chang-Xin Zhou;  Jian-Xia Mo;  Li-Gen Lin;  Li-She Gan
Favorite  |  View/Download:2/0  |  Submit date:2020/07/14
Cyclocarya Paliurus (Juglandaceae)  Seco-dammarane Triterpenoids  Glucose Uptake  Adipocytes  
Deciphering the metabolic role of AMPK in cancer multi-drug resistance Journal article
SEMINARS IN CANCER BIOLOGY, 2018,Volume: 56,Page: 56-71
Authors:  Wen Tan;  Zhangfeng Zhong;  Randy P. Carney;  Yongfan Men;  Jiannan Li;  Tingrui Pan;  Yitao Wang
Favorite  |  View/Download:5/0  |  Submit date:2020/03/27
Ampk  Metabolic Reprogramming  Multi-drug Resistance  Cancer