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Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 10,Page: 1279-1291
Authors:  Lei Fan;  Xiao-xia Qiu;  Zhi-yuan Zhu;  Jian-lu Lv;  Jian Lu;  Fei Mao;  Jin Zhu;  Jia-ying Wang;  Xiao-wei Guan;  Jing Chen;  Jin Ren;  Ji-ming Ye;  Yong-hua Zhao;  Jian Li;  Xu Shen
Favorite  |  View/Download:15/0  |  Submit date:2020/04/14
App/ps1 Transgenic Mice  Alzheimer’s Disease  Autophagy  Inflammation  Nitazoxanide  
The effects of bioactive components from the rhizome of Salvia miltiorrhiza (Danshen) on the characteristics of Alzheimer's disease Journal article
Chinese Medicine, 2019,Volume: 14
Authors:  Cheong‑Meng Chong;  Huanxing Su;  Jin‑Jian Lu;  Yitao Wang
Favorite  |  View/Download:8/0  |  Submit date:2020/03/27
Alzheimer’s Disease  Danshen  Amyloid β Plaques  Neurofbrillary Tangles  Mitochondrial Dysfunction  Autophagy  
The effects of bioactive components from the rhizome of Salvia miltiorrhiza(Danshen) on the characteristics of Alzheimer’s disease Journal article
CHINESE MEDICINE, 2019
Authors:  Cheong‑Meng Chong;  Huanxing Su;  Jin‑Jian Lu;  Yitao Wang
Favorite  |  View/Download:8/0  |  Submit date:2020/04/08
Alzheimer’s Disease  Amyloid β Plaques  Neurofibrillary Tangles  Mitochondrial Dysfunction  Autophagy  Danshen  
Serum amyloid A promotes LPS clearance and suppresses LPS-induced inflammation and tissue injury Journal article
EMBO REPORTS, 2018,Volume: 19,Issue: 10
Authors:  Cheng, Ni;  Liang, Yurong;  Du, Xiaoping;  Ye, Richard D.
View  |  Adobe PDF(2278Kb)  |  Favorite  |  View/Download:544/16  |  Submit date:2018/10/30
acute-phase response  inflammation  innate immunity  lipopolysaccharide  serum amyloid A  
Effects of insulin on transcriptional response and permeability in an in vitro model of human blood-brain barrier Journal article
JOURNAL OF CELLULAR BIOCHEMISTRY, 2018,Volume: 119,Issue: 7,Page: 5657-5664
Authors:  Kuai, Ziyu;  Xu, Yan;  Zhao, Qi;  Liu, Jie;  Guan, Shanshan;  Qiao, Yongbo;  Gong, Xin;  Nie, Jiaojiao;  Li, Pengju;  Liu, Dongni;  Xing, Yifan;  Li, Huiwen;  Sun, Zixiao;  Wang, Wenqi;  Ning, Chunan;  Shi, Yuhua;  Kong, Wei;  Shan, Yaming
Favorite  |  View/Download:36/0  |  Submit date:2018/10/30
Alzheimer's Disease  Human Blood-brain Barrier  Insulin  Type 2 Diabetes  Transcriptional Response  Permeability  
Elevated Expression of Serum Amyloid A 3 Protects Colon Epithelium Against Acute Injury Through TLR2-Dependent Induction of Neutrophil IL-22 Expression in a Mouse Model of Colitis Journal article
FRONTIERS IN IMMUNOLOGY, 2018,Volume: 9
Authors:  Zhang, Gufang;  Liu, Jin;  Wu, Lehao;  Fang, Yu;  Sun, Lei;  Qian, Feng;  Chen, Daijie;  Ye, Richard D.
Favorite  |  View/Download:25/0  |  Submit date:2018/10/30
serum amyloid A  inflammation  innate immunity  cytokines  colitis  neutrophils  
A reciprocal relationship between reactive oxygen species and mitochondrial dynamics in neurodegeneration Journal article
REDOX BIOLOGY, 2018,Volume: 14,Page: 7-19
Authors:  Hung, Clara Hiu-Ling;  Cheng, Sally Shuk-Yee;  Cheung, Yuen-Ting;  Wuwongse, Suthicha;  Zhang, Natalie Qishan;  Ho, Yuen-Shan;  Lee, Simon Ming-Yuen;  Chang, Raymond Chuen-Chung
Favorite  |  View/Download:26/0  |  Submit date:2018/10/30
Alzheimer's Disease  Beta-amyloid  Mitochondria  Fission And Fusion  Drp-1  Neurodegeneration  
SLOH, a carbazole-based fluorophore, mitigates neuropathology and behavioral impairment in the triple-transgenic mouse model of Alzheimer's disease Journal article
NEUROPHARMACOLOGY, 2018,Volume: 131,Page: 351-363
Authors:  Wu, Xiaoli;  Kosaraju, Jayasankar;  Zhou, Wei;  Tam, Kin Yip
Favorite  |  View/Download:14/0  |  Submit date:2018/10/31
Amyloid beta  Aggregation  Alzheimer's disease  3xTg-AD  Neuroprotection  SH-SY5Y  
Injected Amyloid Beta in the Olfactory Bulb Transfers to Other Brain Regions via Neural Connections in Mice Journal article
MOLECULAR NEUROBIOLOGY, 2018,Volume: 55,Issue: 2,Page: 1703-1713
Authors:  He, Baixuan;  Zheng, Minying;  Liu, Qiang;  Shi, Zhe;  Long, Simei;  Lu, Xilin;  Pei, Zhong;  Yuan, Ti-Fei;  Su, Huanxing;  Yao, Xiaoli
Favorite  |  View/Download:19/0  |  Submit date:2018/10/30
Alzheimer's Disease  Oligomers  Olfactory Pathway  Neural Connections  Apoptosis  
Human amyloid β peptide and tau co-expression impairs behavior and causes specific gene expression changes in Caenorhabditis elegans Journal article
Neurobiology of Disease, 2018,Volume: 109,Page: 88-101
Authors:  Wang C.;  Saar V.;  Leung K.L.;  Chen L.;  Wong G.
Favorite  |  View/Download:7/0  |  Submit date:2018/12/18
Alzheimer's Disease  Amyloid Beta  Caenorhabditis Elegans  Rna Interference  Tau  Transcriptome Analysis