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Expression of Programmed Cell Death-Ligands in Hepatocellular Carcinoma: Correlation With Immune Microenvironment and Survival Outcomes Journal article
FRONTIERS IN ONCOLOGY, 2019,Volume: 9
Authors:  Haotian Liao;  Wen Chen;  Yunlu Dai;  Joseph J. Richardson;  Junling Guo;  Kefei Yuan;  Yong Zeng;  Kunlin Xie
Favorite  |  View/Download:41/0  |  Submit date:2020/05/12
Programmed Cell Death-ligands  Macrophage  Tumor Immune Stroma  Tumor Microenvironment  Antipd-1 Axis Therapy  Hepatocellular Carcinoma  
Alpinia zerumbet(Pers.): Food and Medicinal Plant with Potential In Vitro and In Vivo Anti-Cancer Activities Journal article
MOLECULES, 2019,Volume: 24,Issue: 13
Authors:  Maram Hussein Zahra;  Tarek A.R. Salem;  Bishoy El-Aarag;  Nermeen Yosri;  Samah EL-Ghlban;  Kholoud Zaki;  Amel H. Marei;  Aida Abd El-Wahed;  Aamer Saeed;  Alfi Khatib;  Mohamed F. AlAjmi;  Abdulrahman M. Shathili;  Jianbo Xiao;  Shaden A. M. Khalifa;  Hesham R. El-Seedi
Favorite  |  View/Download:11/0  |  Submit date:2020/04/24
5,6-dehydrokawain  Alpinia Zerumbet  Ehrlich Ascites Carcinoma  Anti-oxidant  Anti-tumor  
TNFR2 and Regulatory T Cells: Potential Immune Checkpoint Target in Cancer Immunotherapy Book chapter
出自: Progress in Molecular Biology and Translational Science:ELSEVIER ACADEMIC PRESS INC, 525 B STREET, SUITE 1900, SAN DIEGO, CA 92101-4495 USA, 2019, 页码: 101-117
Authors:  Jiang He;  Ruixin Li;  Yibo Chen;  Yuanjia Hu;  Xin Chen
Favorite  |  View/Download:5/0  |  Submit date:2020/05/05
Regulatory t Cells  Tumor Necrosis Factor Receptor Type 2  Cancer  Immunotherapy  Tumor Necrosis Factor  
Combined use of arginase and dichloroacetate exhibits anti-proliferative effects in triple negative breast cancer cells Journal article
JOURNAL OF PHARMACY AND PHARMACOLOGY, 2019,Volume: 71,Issue: 3,Page: 306-315
Authors:  Angela Verma;  Yau-Min Lam;  Yun-Chung Leung;  Xiaohui Hu;  Xin Chen;  Edwin Cheung;  Kin Yip Tam
Favorite  |  View/Download:16/0  |  Submit date:2020/05/21
Bacillus Caldovelox Arginase  Breast Cancer  Dichloroacetate  Drug Combination  Pegyated Human Arginase  
Structure-Based Discovery of a Selective KDM5A Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines Journal article
CANCERS, 2019,Volume: 11,Issue: 1
Authors:  Yang, GJ;  Ko, CN;  Zhong, HJ;  Leung, CH;  Ma, DL
Favorite  |  View/Download:10/0  |  Submit date:2020/03/24
Cell Cycle Arrest  Kdm5a  Jumonji Domain  Histone Demethylation  Protein-protein Interaction  Virtual Screening  Breast Cancer  Cell Senescence  
TNFR2-expressing CD4(+) Foxp3(+) regulatory T cells in cancer immunology and immunotherapy Journal article
Progress in Molecular Biology and Translational Science, 2019
Authors:  Jiang He;  Ruixin Li;  Yibo Chen;  Yuanjia Hu;  Xin Chen
Favorite  |  View/Download:21/0  |  Submit date:2019/05/08
Regulatory t Cells  Immunotherapy  Cancer  Tumor Necrosis Factor Receptor Type 2  Tumor Necrosis Factor  
LFB: A Novel Antimicrobial Brevinin-Like Peptide from the Skin Secretion of the Fujian Large Headed Frog, Limnonectes fujianensi Journal article
BIOMOLECULES, 2019,Volume: 9,Issue: 6
Authors:  Bin Li;  Peng Lyu;  Shuping Xie;  Haixin Qin;  Wenyuan Pu;  Houxi Xu;  Tianbao Chen;  Chris Shaw;  Lilin Ge;  Hang Fai Kwok
Favorite  |  View/Download:6/0  |  Submit date:2020/05/20
Amphibian  Brevinin-like Peptide  Antimicrobial Peptides  Drug Discovery  
Serially coupled reversed phase-hydrophilic interaction liquid chromatography-tailored multiple reaction monitoring, a fit-for-purpose tool for large-scale targeted metabolomics of medicinal bile Journal article
ANALYTICA CHIMICA ACTA, 2018,Volume: 1037,Page: 119-129
Authors:  Song, Qingqing;  Liu, Wenjing;  Chen, Xiaojia;  Li, Jun;  Li, Peng;  Yang, Fengqing;  Wang, Yitao;  Song, Yuelin;  Tu, Pengfei
Adobe PDF(1652Kb)  |  Favorite  |  View/Download:797/3  |  Submit date:2018/10/30
Large-scale Targeted Metabolomics  Serially Coupled Rplc-hilic  Tailored Multiple Reaction Monitoring  Medicinal Bile  Bile Acids  
Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships Journal article
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018,Volume: 28,Issue: 21,Page: 3441-3445
Authors:  Zhang, Shao-Lin;  Yang, Zheng;  Hu, Xiaohui;  Tam, Kin Yip
Favorite  |  View/Download:17/0  |  Submit date:2018/10/30
Pyruvate dehydrogenase kinase  Pyruvate dehydrogenase complex  Antiproliferative activity  Dichloroacetophenone  Kinase inhibition  
Inhibition of pyruvate dehydrogenase kinase 1 enhances the anti-cancer effect of EGFR tyrosine kinase inhibitors in non-small cell lung cancer Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 838,Page: 41-52
Authors:  Yang, Zheng;  Zhang, Shao-Lin;  Hu, Xiaohui;  Tam, Kin Yip
Favorite  |  View/Download:27/0  |  Submit date:2018/10/30
Dichloroacetophenone  Epidermal Growth Factor Receptor  Tyrosine Kinase Inhibitor  Synergism  Hypoxia  Oxidative Phosphorylation