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Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 10,Page: 1279-1291
Authors:  Lei Fan;  Xiao-xia Qiu;  Zhi-yuan Zhu;  Jian-lu Lv;  Jian Lu;  Fei Mao;  Jin Zhu;  Jia-ying Wang;  Xiao-wei Guan;  Jing Chen;  Jin Ren;  Ji-ming Ye;  Yong-hua Zhao;  Jian Li;  Xu Shen
Favorite  |  View/Download:15/0  |  Submit date:2020/04/14
App/ps1 Transgenic Mice  Alzheimer’s Disease  Autophagy  Inflammation  Nitazoxanide  
Oral Delivery of Puerarin Nanocrystals To Improve Brain Accumulation and Anti-Parkinsonian Efficacy Journal article
MOLECULAR PHARMACEUTICS, 2019,Volume: 16,Issue: 4,Page: 1444-1455
Authors:  Sha Xiong;  Wei Liu;  Dongli Li;  Xiaojia Chen;  Fang Liu;  Dongsheng Yuan;  Huafeng Pan;  Qi Wang;  Shuhuan Fang;  Tongkai Chen
Favorite  |  View/Download:9/0  |  Submit date:2020/01/06
Parkinson’s Disease  Brain Accumulation  Nanocrystals  Oral Delivery  Puerarin  
Canthin-6-One Accelerates Alpha-Synuclein Degradation by Enhancing UPS Activity: Drug Target Identification by CRISPR-Cas9 Whole Genome-Wide Screening Technology Journal article
FRONTIERS IN PHARMACOLOGY, 2019
Authors:  Ning-Ning Yuan;  Cui-Zan Cai;  Ming-Yue Wu;  Qi Zhu;  HuanXing Su;  Min Li;  JiaoYan Ren;  Jie-Qiong Tan;  Jia-Hong Lu
Favorite  |  View/Download:24/0  |  Submit date:2020/04/14
Canthin-6-one  Parkinson’s Disease  Alpha-synuclein  Ubiquitin-proteasome-system  Crispr/cas9  Rpn2/psmd1  Pka  
Phototheranostics: Active Targeting of Orthotopic Glioma Using Biomimetic Proteolipid Nanoparticles Journal article
ACS NANO, 2019,Volume: 13,Issue: 1,Page: 386-398
Authors:  Yali Jia;  Xiaobing Wang;  Dehong Hu;  Pan Wang;  Quanhong Liu;  Xuanjun Zhang;  Jingying Jiang;  Xin Liu;  Zonghai Sheng;  Bin Liu;  Hairong Zheng
Favorite  |  View/Download:7/0  |  Submit date:2020/05/26
Biomimetic Engineering  Phototheranostics  Glioma  Blood-brain Barrier  Photothermal Therapy  
Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
View  |  Adobe PDF(2009Kb)  |  Favorite  |  View/Download:1016/75  |  Submit date:2018/10/30
Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
UPLC/Q-TOFMS-Based Metabolomics Approach to Reveal the Protective Role of Other Herbs in An-Gong-Niu-Huang Wan Against the Hepatorenal Toxicity of Cinnabar and Realgar Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Xia, Fangbo;  Li, Ao;  Chai, Yushuang;  Xiao, Xiao;  Wan, Jianbo;  Li, Peng;  Wang, Yitao
View  |  Adobe PDF(3535Kb)  |  Favorite  |  View/Download:539/23  |  Submit date:2018/10/30
An-gong-niu-huang Wan  Cinnabar  Realgar  Metabonomics  Detoxification  Inflammation  
A Novel Tetramethylpyrazine Derivative Prophylactically Protects against Glutamate-Induced Excitotoxicity in Primary Neurons through the Blockage of N-Methyl-D-aspartate Receptor Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Hu, Shengquan;  Hu, Huihui;  Mak, Shinghung;  Cui, Guozhen;  Lee, Mingyuen;  Shan, Luchen;  Wang, Yuqiang;  Lin, Huangquan;  Zhang, Zaijun;  Han, Yifan
Favorite  |  View/Download:23/0  |  Submit date:2018/10/30
Alzheimer's disease  tetramethylpyrazine derivative  NMDA receptor  neuroprotection  oxidative stress  GSK3 beta  
Injected Amyloid Beta in the Olfactory Bulb Transfers to Other Brain Regions via Neural Connections in Mice Journal article
MOLECULAR NEUROBIOLOGY, 2018,Volume: 55,Issue: 2,Page: 1703-1713
Authors:  He, Baixuan;  Zheng, Minying;  Liu, Qiang;  Shi, Zhe;  Long, Simei;  Lu, Xilin;  Pei, Zhong;  Yuan, Ti-Fei;  Su, Huanxing;  Yao, Xiaoli
Favorite  |  View/Download:19/0  |  Submit date:2018/10/30
Alzheimer's Disease  Oligomers  Olfactory Pathway  Neural Connections  Apoptosis  
gamma-Mangostin, a xanthone from mangosteen, attenuates oxidative injury in liver via NRF2 and SIRT1 induction Journal article
JOURNAL OF FUNCTIONAL FOODS, 2018,Volume: 40,Page: 544-553
Authors:  Wang, Anqi;  Li, Dan;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Lin, Ligen
View  |  Adobe PDF(1410Kb)  |  Favorite  |  View/Download:515/19  |  Submit date:2018/10/30
Gamma-mangostin  Mangosteen  Liver Oxidative Injury  Nrf2  Sirt1  Pgc-1 Alpha  
Zebrafish: A Visual Model to Evaluate the Biofate of Transferrin Receptor-Targeted 7Peptide-Decorated Coumarin 6 Micelles Journal article
ACS Applied Materials and Interfaces, 2017,Volume: 9,Issue: 44,Page: 39048-39058
Authors:  Ye Li;  Xiaoning Song;  Xiang Yi;  Ruibing Wang;  Simon Ming-Yuen Lee;  Xueqing Wang;  Ying Zheng
Favorite  |  View/Download:13/0  |  Submit date:2018/11/06
7peptide  Biological Barriers  Ligand Density  Poly(Ethylene Glycol)-block-Poly(Ε-caprolactone) Micelles  Transferrin Receptor  Zebrafish