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Computer-Aided Formulation Design for a Highly Soluble Lutein-Cyclodextrin Multiple-Component Delivery System Journal article
MOLECULAR PHARMACEUTICS, 2018,Volume: 15,Issue: 4,Page: 1664-1673
Authors:  Zhao, Qianqian;  Miriyala, Nikhila;  Su, Yan;  Chen, Weijie;  Gao, Xuejiao;  Shao, Ling;  Yan, Ru;  Li, Haifeng;  Yao, Xiaojun;  Cao, Dongsheng;  Wang, Yitao;  Ouyang, Defang
View  |  Adobe PDF(4697Kb)  |  Favorite  |  View/Download:786/57  |  Submit date:2018/10/30
Lutein  Cyclodextrin  Multiple-component System  Molecular Dynamics Simulation  Bioavailability  Computer-aided Formulation Design  
Mori Cortex regulates P-glycoprotein in Caco-2 cells and colons from rats with experimental colitis via direct and gut microbiota-mediated mechanisms Journal article
RSC ADVANCES, 2017,Volume: 7,Issue: 5,Page: 2594-2605
Authors:  Jing, Wanghui;  Gao, Xuejiao;  Han, Beilei;  Wei, Bin;  Hu, Nan;  Li, Sai;  Yan, Ru;  Wang, Yitao
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Metabolic characterization of (±)-praeruptorin A in vitro and in vivo by high performance liquid chromatography coupled with hybrid triple quadrupole-linear ion trap mass spectrometry and time-of-flight mass spectrometry Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2014,Volume: 90,Issue: 5,Page: 98-110
Authors:  Song, Yue-Lin;  Jing, Wang-Hui;  Yan, Ru;  Wang, Yi-Tao
View  |  Adobe PDF(3404Kb)  |  Favorite  |  View/Download:453/8  |  Submit date:2018/11/01
(+/-)-praeruptorin a  Metabolism  Lightsight (Tm) Software  In Vivo  Peucedani Radix  
Simultaneously enantiospecific determination of (+)-trans-khellactone, (+/-)-praeruptorin A, (+/-)-praeruptorin B, (+)-praeruptorin E, and their metabolites, (+/-)-cis-khellactone, in rat plasma using Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2014,Volume: 88,Issue: 1,Page: 269-277
Authors:  Song, Yuelin;  Jing, Wanghui;  Yang, Fengqing;  Shi, Zhan;  Yao, Meicun;  Yan, Ru;  Wang, Yitao
View  |  Adobe PDF(488Kb)  |  Favorite  |  View/Download:542/58  |  Submit date:2018/11/01
Online Spe  Chiral Lc-ms/ms  Enantiospecific  Peucedani Radix  Pharmacokinetics  
Enantioseparation and Absolute Configuration Determination of Angular-Type Pyranocoumarins from Peucedani Radix Using Enzymatic Hydrolysis and Chiral HPLC-MS/MS Analysis Journal article
MOLECULES, 2012,Volume: 17,Issue: 4,Page: 4236-4251
Authors:  Song, YL (Song, Yue-Lin);  Zhang, QW (Zhang, Qing-Wen);  Li, YP (Li, Ya-Ping);  Yan, R (Yan, Ru);  Wang, YT (Wang, Yi-Tao)
View  |  Adobe PDF(384Kb)  |  Favorite  |  View/Download:493/6  |  Submit date:2018/11/01
Absolute Configuration  Angular-type Pyranocoumarins  Chiral Lc-ms/ms  Cis-khellactone  Enzymatic Hydrolysis  
Stereoselective metabolism of (+/-)-praeruptorin A, a calcium channel blocker from Peucedani Radix, in pooled liver microsomes of rats and humans Journal article
XENOBIOTICA, 2012,Volume: 42,Issue: 3,Page: 221-237
Authors:  Song, YL (Song, Y. L.);  ing, WH (Jing, W. H.);  Zhao, HY (Zhao, H. Y.);  Yan, R (Yan, R.);  Li, PT (Li, P. T.);  Wang, YT (Wang, Y. T.)
Favorite  |  View/Download:24/0  |  Submit date:2018/11/01
Aninitric-oxide Production  Caco-2 Cell Monolayers  Anti-aids Agents  Angelica-furcijuga  In-vitro  Inhibitory-activities  Human Cytochrome-p450  Species-differences  Cancer-cells  Qian-hu  
Intestinal transport of scutellarein and scutellarin and first-pass metabolism by UDP-glucuronosyltransferase-mediated glucuronidation of scutellarein and hydrolysis of scutellarin Journal article
Xenobiotica, 2011,Volume: 41,Issue: 7,Page: 538-548
Authors:  Yazhi Wang;  Heisio Ao;  Zhengming Qian;  Ying Zheng
Favorite  |  View/Download:9/0  |  Submit date:2020/04/09
Udp-glucuronosyltransferase  Scutellarein (s)  Scutellarin (Sg)  Caco-2 Cell Monolayer  Glucuronidation  
Transport and metabolism of (+/-)-praeruptorin A in Caco-2 cell monolayers Journal article
XENOBIOTICA, 2011,Volume: 41,Issue: 1,Page: 71-81
Authors:  Jing, W. H.;  Song, Y. L.;  Yan, R.;  Bi, H. C.;  Li, P. T.;  Wang, Y. T.
Favorite  |  View/Download:17/0  |  Submit date:2018/11/01
Intestinal-absorption  Gene-expression  Drug Transport  Human Liver  Permeability  Carboxylesterases  Enantiomers  Ester  
Transport and metabolism of (±)-praeruptorin A in Caco-2 cell monolayers Journal article
Xenobiotica, 2011,Volume: 41,Issue: 1,Page: 71
Authors:  Jing W.H.;  Song Y.L.;  Yan R.;  Bi H.C.;  Li P.T.;  Wang Y.T.
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(±)-praeruptorin a  Caco-2 Cells  Enantioselectivity  Hydrolysis  Metabolism  Transport  
Study on absorption mechanisms of Zedoary Turmeric oil by Caco-2 cell model Journal article
Chinese Pharmaceutical Journal, 2007,Volume: 42,Issue: 16,Page: 1228
Authors:  Leng W.;  Zheng Y.;  Li S.-P.;  Yang F.-Q.;  Wang Y.-T.
Favorite  |  View/Download:6/0  |  Submit date:2018/10/31
Absorption mechanism  Caco-2 cell absorption model  Passive diffusion  Zedoary turmeric oil