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A Danshensu-Tetramethylpyrazine Conjugate DT-010 Overcomes Multidrug Resistance in Human Breast Cancer Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:  Xinhua Zhou;  Anqi Wang;  Liang Wang;  Jianhua Yin;  Li Wang;  Lijun Di;  Maggie Pui-Man Hoi;  Luchen Shan;  Xu Wu;  Yuqiang Wang
Favorite | View/Download:12/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2020/05/21
Danshensu  Tetramethylpyrazine  Breast Cancer  Resistance  Glycolysis  P-glycoprotein  
A Catalase-Like Metal-Organic Framework Nanohybrid for O2-Evolving Synergistic Chemoradiotherapy Journal article
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019,Volume: 58,Issue: 26,Page: 8752-8756
Authors:  Zhimei He;  Xiaolin Huang;  Chen Wang;  Xiangli Li;  Yijing Liu;  Yijing Liu;  Zijian Zhou;  Sheng Wang;  Fuwu Zhang;  Zhantong Wang;  Orit Jacobson;  Jun‐Jie Zhu;  Guocan Yu;  Yunlu Dai;  Xiaoyuan Chen
Favorite | View/Download:40/0 | TC[WOS]:15 TC[Scopus]:0 | Submit date:2020/05/13
CuS Nanoparticles as a Photodynamic Nanoswitch for Abrogating Bypass Signaling To Overcome Gefitinib Resistance Journal article
NANO LETTERS, 2019,Volume: 19,Issue: 5,Page: 3344-3352
Authors:  Xiajing Gu;  Yuanyuan Qiu;  Miao Lin;  Kai Cui;  Gaoxian Chen;  Yingzhi Chen;  Chenchen Fan;  Yongming Zhang;  Lu Xu;  Hongzhuan Chen;  Jian-Bo Wan;  Wei Lu;  Zeyu Xiao
Favorite | View/Download:9/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2020/04/22
Gefitinib  Cus Nanoparticles  Non-small Cell Lung Cancer  Rug Resistance  Active Oxygen Species  
Combined use of arginase and dichloroacetate exhibits anti-proliferative effects in triple negative breast cancer cells Journal article
JOURNAL OF PHARMACY AND PHARMACOLOGY, 2019,Volume: 71,Issue: 3,Page: 306-315
Authors:  Angela Verma;  Yau-Min Lam;  Yun-Chung Leung;  Xiaohui Hu;  Xin Chen;  Edwin Cheung;  Kin Yip Tam
Favorite | View/Download:16/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2020/05/21
Bacillus Caldovelox Arginase  Breast Cancer  Dichloroacetate  Drug Combination  Pegyated Human Arginase  
Structure-Based Discovery of a Selective KDM5A Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines Journal article
CANCERS, 2019,Volume: 11,Issue: 1
Authors:  Yang, GJ;  Ko, CN;  Zhong, HJ;  Leung, CH;  Ma, DL
Favorite | View/Download:10/0 | TC[WOS]:7 TC[Scopus]:0 | Submit date:2020/03/24
Cell Cycle Arrest  Kdm5a  Jumonji Domain  Histone Demethylation  Protein-protein Interaction  Virtual Screening  Breast Cancer  Cell Senescence  
A pH-driven ring translocation switch against cancer cells Journal article
CHEMICAL COMMUNICATIONS, 2018,Volume: 54,Issue: 98,Page: 13825-13828
Authors:  Cheng, Qian;  Yin, Hang;  Rosas, Roselyne;  Gigmes, Didier;  Ouari, Olivier;  Wang, Ruibing;  Kermagoret, Anthony;  Bardelang, David
Favorite | View/Download:14/0 | TC[WOS]:4 TC[Scopus]:0 | Submit date:2019/01/17
Inhibition of lung cancer by 2-methoxy-6-acetyl-7-methyljuglone (MAM) through induction of necroptosis by targeting receptor-interacting protein 1 (RIP1) Journal article
Antioxidants & Redox Signaling, 2018,Volume: 0,Issue: JA
Authors:  Sun W;  Yu J;  Gao H;  Wu X;  Wang S;  Hou Y;  Lu JJ;  Chen X
Favorite | View/Download:14/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2019/01/16
G-Quadruplex-Based Nanoscale Coordination Polymers to Modulate Tumor Hypoxia and Achieve Nuclear-Targeted Drug Delivery for Enhanced Photodynamic Therapy Journal article
Nano Letters, 2018,Volume: 18,Issue: 11,Page: 6867-6875
Authors:  Yang Y.;  Zhu W.;  Feng L.;  Chao Y.;  Yi X.;  Dong Z.;  Yang K.;  Tan W.;  Liu Z.;  Chen M.W
Favorite | View/Download:14/0 | TC[WOS]:28 TC[Scopus]:0 | Submit date:2018/12/27
Dna Nanostructure  G-quadruplex  Nanoscale Coordination-polymers  Ncps  Photodynamic Therapy  Tumor Hypoxia  
Inhibition of pyruvate dehydrogenase kinase 1 enhances the anti-cancer effect of EGFR tyrosine kinase inhibitors in non-small cell lung cancer Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 838,Page: 41-52
Authors:  Yang, Zheng;  Zhang, Shao-Lin;  Hu, Xiaohui;  Tam, Kin Yip
Favorite | View/Download:28/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2018/10/30
Dichloroacetophenone  Epidermal Growth Factor Receptor  Tyrosine Kinase Inhibitor  Synergism  Hypoxia  Oxidative Phosphorylation  
Rapid identification of antimicrometastases drugs using integrated model systems with two dimensional monolayer, three dimensional spheroids, and zebrafish xenotransplantation tumors Journal article
BIOTECHNOLOGY AND BIOENGINEERING, 2018,Volume: 115,Issue: 11,Page: 2828-2843
Authors:  Fu, Afu;  Peh, Yu Ming;  Ngan, Weida;  Wei, Na;  Luo, Kathy Qian
Favorite | View/Download:10/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2019/01/17
antimetastasis drug discovery  fluorescence resonance energy transfer  PI3K  AKT pathway  three dimensional tumor spheroids  zebrafish xenograft tumor model