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A novel agent attenuates cardiotoxicity and improves antitumor activity of doxorubicin in breast cancer cells Journal article
JOURNAL OF CELLULAR BIOCHEMISTRY, 2019,Volume: 120,Issue: 4,Page: 5913-5922
Authors:  Ying Zhang;  Hongkuan Deng;  Hefeng Zhou;  Yucong Lu;  Luchen Shan;  Simon Ming‐Yuen Lee;  Guozhen Cui
Favorite | View/Download:243/0 | TC[WOS]:6 TC[Scopus]:0 | Submit date:2020/01/16
Antitumor  Biotin-conjugated Adtm Analog (Baa)  Cardioprotection  Cardiotoxicity  Doxorubicin (Dox)  
A novel Ca2+ current blocker promotes angiogenesis and cardiac healing after experimental myocardial infarction in mice Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 134,Page: 109-117
Authors:  Cui, Guozhen;  Xin, Qiqi;  Tseng, Hisa Hui Ling;  Hoi, Maggie PuiMan;  Wang, Yan;  Yang, Binrui;  Choi, InLeng;  Wang, Yuqiang;  Yuan, Rong;  Chen, Keji;  Cong, Weihong;  Lee, Simon MingYuen
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Cardioprotection  Angiogenesis  ADTM  Zebrafish  VEGF  
A novel Ca2+ current blocker promotes angiogenesis and cardiac healing after experimental myocardial infarction in mice Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 134,Page: 109-117
Authors:  Guozhen Cui;  Qiqi Xin;  Hisa Hui Ling Tseng;  Maggie PuiMan Hoi;  Yan Wang;  Binrui Yang;  InLeng Choi;  Yuqiang Wang;  Rong Yuan;  Keji Chen;  Weihong Cong;  Simon MingYuen Lee
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Cardioprotection  Angiogenesis  Adtm  Zebrafish  Vegf  
A novel ShK-like toxic peptide fromthe transcriptome of the cnidarian Palythoa caribaeorum displays neuroprotection and cardioprotection in zebrafish Journal article
Toxins, 2018,Volume: 10,Issue: 6
Authors:  Liao Q.;  Gong G.;  Siu S.W.I.;  Wong C.T.T.;  Yu H.;  Tse Y.C.;  Radis-Baptista G.;  Lee S.M.-Y.
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Animal toxins  Calcium-activated K+ ion channel  Dynamics simulation  ShK-like peptide  Voltage-gated K+ ion channel  Zoantharian  
A Novel ShK-Like Toxic Peptide from the Transcriptome of the Cnidarian Palythoa caribaeorum Displays Neuroprotection and Cardioprotection in Zebrafish Journal article
TOXINS, 2018,Volume: 10,Issue: 6
Authors:  Liao, Qiwen;  Gong, Guiyi;  Siu, Shirley Weng In;  Wong, Clarence Tsun Ting;  Yu, Huidong;  Tse, Yu Chung;  Radis-Baptista, Gandhi;  Lee, Simon Ming-Yuen
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Zoantharian  Shk-like Peptide  Dynamics Simulation  Voltage-gated K++ Ion Channel  Calcium-activated K++ Ion Channel  Animal Toxins  
A novel compound DT-010 protects against doxorubicin-induced cardiotoxicity in zebrafish and H9c2 cells by inhibiting reactive oxygen species-mediated apoptotic and autophagic pathways Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 820,Page: 86-96
Authors:  Tang, Fan;  Zhou, Xinhua;  Wang, Liang;  Shan, Luchen;  Li, Chuwen;  Zhou, Hefeng;  Lee, Simon Ming-Yuen;  Hoi, Maggie Pui-Man
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Cardioprotection  Anti-oxidative Stress  Anti-apoptosis  Autophagy Regulation  Zebrafish Cardiotoxicity  H9c2 Cardiomyocytes  
Extract of Sheng-Mai-San ameliorates myocardial Ischemia-Induced heart failure by modulating ca2+-Calcineurin-Mediated DRP1 signaling pathways Journal article
International Journal of Molecular Sciences, 2017,Volume: 18,Issue: 9
Authors:  Yang Y.;  Tian Y.;  Hu S.;  Bi S.;  Li S.;  Hu Y.;  Kou J.;  Qi J.;  Yu B.
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Calcineurin A  Dynamin-related protein 1  Extract of Sheng-Mai-San  Heart failure  Mitochondrial fission  
Extract of Sheng-Mai-San Ameliorates Myocardial Ischemia-Induced Heart Failure by Modulating Ca2+-Calcineurin-Mediated Drp1 Signaling Pathways Journal article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017,Volume: 18,Issue: 9
Authors:  Yang, Ye;  Tian, Yushan;  Hu, Siyao;  Bi, Suxia;  Li, Suxia;  Hu, Yuanjia;  Kou, Junping;  Qi, Jin;  Yu, Boyang
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extract of Sheng-Mai-San  heart failure  calcineurin A  dynamin-related protein 1  mitochondrial fission  
Dickkopf-3 protects against cardiac dysfunction and ventricular remodelling following myocardial infarction Journal article
Basic Research in Cardiology, 2015,Volume: 110,Issue: 3
Authors:  Bao M.-W.;  Cai Z.;  Zhang X.-J.;  Li L.;  Liu X.;  Wan N.;  Hu G.;  Wan F.;  Zhang R.;  Zhu X.;  Xia H.;  Li H.
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Apoptosis  ASK1  Cardiac remodelling  DKK3  Inflammation  Myocardial infarction  
Cytoprotection of baicalein against oxidative stress-induced cardiomyocytes injury through the Nrf2/Keap1 pathway Journal article
Journal of Cardiovascular Pharmacology, 2015,Volume: 65,Issue: 1,Page: 39-46
Authors:  Cui, Guozhen;  Chui Wah Luk, Sharon;  Li, Ronald Adolphus;  Chan, Ken Kwok Keung;  Lei, Si Wan;  Wang, Liang;  Shen, Huifang;  Leung, George Pak Heng;  Lee, Simon Ming Yuen
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Baicalein  Cardioprotection  Nrf2  Oxidative Stress