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Cardiotoxicity of forchlorfenuron (CPPU) in zebrafish (Danio rerio) and H9c2 cardiomyocytes Journal article
CHEMOSPHERE, 2019,Volume: 235,Page: 153-162
Authors:  Guiyi Gong;  Hiotong Kam;  Yuchung Tse;  Simon Mingyuen Lee
Favorite  |  View/Download:295/0  |  Submit date:2020/01/15
Forchlorfenuron (Cppu)  Zebrafish  Cardiotoxicity  Hematopoietic Toxicity  H9c2 Cardiomyocytes  Cytoskeletons Destruction  
A Danshensu-Tetramethylpyrazine Conjugate DT-010 Overcomes Multidrug Resistance in Human Breast Cancer Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:  Xinhua Zhou;  Anqi Wang;  Liang Wang;  Jianhua Yin;  Li Wang;  Lijun Di;  Maggie Pui-Man Hoi;  Luchen Shan;  Xu Wu;  Yuqiang Wang
Favorite  |  View/Download:9/0  |  Submit date:2020/05/21
Danshensu  Tetramethylpyrazine  Breast Cancer  Resistance  Glycolysis  P-glycoprotein  
A novel agent attenuates cardiotoxicity and improves antitumor activity of doxorubicin in breast cancer cells Journal article
JOURNAL OF CELLULAR BIOCHEMISTRY, 2019,Volume: 120,Issue: 4,Page: 5913-5922
Authors:  Ying Zhang;  Hongkuan Deng;  Hefeng Zhou;  Yucong Lu;  Luchen Shan;  Simon Ming‐Yuen Lee;  Guozhen Cui
Favorite  |  View/Download:242/0  |  Submit date:2020/01/16
Antitumor  Biotin-conjugated Adtm Analog (Baa)  Cardioprotection  Cardiotoxicity  Doxorubicin (Dox)  
Supramolecular strategy for reducing the cardiotoxicity of bedaquiline without compromising its antimycobacterial efficacy Conference paper
FOOD AND CHEMICAL TOXICOLOGY, Kunming, PEOPLES R CHINA, AUG 25-30, 2018
Authors:  Kuok, Kit Ieng;  Ng, Phoebe Choi In;  Ji, Xia;  Wang, Chunming;  Yew, Wing Wai;  Chan, Denise P. C.;  Zheng, Jun;  Lee, Simon M. Y.;  Wang, Ruibing
View  |  Adobe PDF(423Kb)  |  Favorite  |  View/Download:586/43  |  Submit date:2018/10/30
Cucurbit[7]Uril  Bedaquiline  Supramolecular Formulation  Cardiotoxicity  Antimycobacterial  
A novel Ca2+ current blocker promotes angiogenesis and cardiac healing after experimental myocardial infarction in mice Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 134,Page: 109-117
Authors:  Cui, Guozhen;  Xin, Qiqi;  Tseng, Hisa Hui Ling;  Hoi, Maggie PuiMan;  Wang, Yan;  Yang, Binrui;  Choi, InLeng;  Wang, Yuqiang;  Yuan, Rong;  Chen, Keji;  Cong, Weihong;  Lee, Simon MingYuen
View  |  Adobe PDF(3018Kb)  |  Favorite  |  View/Download:503/15  |  Submit date:2018/10/30
Cardioprotection  Angiogenesis  ADTM  Zebrafish  VEGF  
Self-stabilized silk sericin-based nanoparticles: In vivo biocompatibility and reduced doxorubicin-induced toxicity Journal article
ACTA BIOMATERIALIA, 2018,Volume: 74,Page: 385-396
Authors:  Hu, Doudou;  Li, Ting;  Xu, Zongpu;  Liu, Di;  Yang, Mingying;  Zhu, Liangjun
Favorite  |  View/Download:19/0  |  Submit date:2018/10/30
Colloidal stability  Hydrophilicity  Water-soluble silk sericin  Freeze-drying  Dispersion stabilizer  Cryoprotectant  Doxorubicin  
Diethyl blechnic, a novel natural product isolated from salvia miltiorrhiza bunge, inhibits doxorubicin-induced apoptosis by inhibiting ROS and activating JNK1/2 Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 6
Authors:  Yu J.;  Gao H.;  Wu C.;  Xu Q.-M.;  Lu J.-J.;  Chen X.
Favorite  |  View/Download:8/0  |  Submit date:2018/12/28
Cardiotoxicity  Diethyl Blechnic  Dox  Jnk1/2  Ros  
Supramolecular Encapsulation and Bioactivity Modulation of a Halonium Ion by Cucurbit [n] uril (n = 7, 8) Journal article
Journal of Organic Chemistry, 2018,Volume: 83,Issue: 8,Page: 4882-4887
Authors:  Yin H.;  Huang Q.;  Zhao W.;  Bardelang D.;  Siri D.;  Chen X.;  Lee S.M.Y.;  Wang R.
Favorite  |  View/Download:9/0  |  Submit date:2018/11/06
Supramolecular Encapsulation and Bioactivity Modulation of a Halonium Ion by Cucurbit[n]uril (n=7, 8) Journal article
JOURNAL OF ORGANIC CHEMISTRY, 2018,Volume: 83,Issue: 8,Page: 4882-4887
Authors:  Yin, Hang;  Huang, Qiaoxian;  Zhao, Wenwen;  Bardelang, David;  Siri, Didier;  Chen, Xiuping;  Lee, Simon M. Y.;  Wang, Ruibing
Favorite  |  View/Download:32/0  |  Submit date:2018/10/30
A novel compound DT-010 protects against doxorubicin-induced cardiotoxicity in zebrafish and H9c2 cells by inhibiting reactive oxygen species-mediated apoptotic and autophagic pathways Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 820,Page: 86-96
Authors:  Tang, Fan;  Zhou, Xinhua;  Wang, Liang;  Shan, Luchen;  Li, Chuwen;  Zhou, Hefeng;  Lee, Simon Ming-Yuen;  Hoi, Maggie Pui-Man
Favorite  |  View/Download:21/0  |  Submit date:2018/10/30
Cardioprotection  Anti-oxidative Stress  Anti-apoptosis  Autophagy Regulation  Zebrafish Cardiotoxicity  H9c2 Cardiomyocytes