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NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Miao,Kai;  Lei,Josh Haipeng;  Valecha,Monica Vishnu;  Zhang,Aiping;  Xu,Jun;  Wang,Lijian;  Lyu,Xueying;  Chen,Si;  Miao,Zhengqiang;  Zhang,Xin;  Su,Sek Man;  Shao,Fangyuan;  Rajendran,Barani Kumar;  Bao,Jiaolin;  Zeng,Jianming;  Sun,Heng;  Chen,Ping;  Tan,Kaeling;  Chen,Qiang;  Wong,Koon Ho;  Xu,Xiaoling;  Deng,Chu Xia
Favorite | View/Download:1/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/09/16
Rmrp Mutation Disrupts Chondrogenesis and Bone Ossification in Zebrafish Model of Cartilage-Hair Hypoplasia via Enhanced Wnt/β-Catenin Signaling Journal article
Journal of Bone and Mineral Research, 2019,Volume: 34,Issue: 11,Page: 2101-2116
Authors:  Sun,Xianding;  Zhang,Ruobin;  Liu,Mi;  Chen,Hangang;  Chen,Liang;  Luo,Fengtao;  Zhang,Dali;  Huang,Junlan;  Li,Fangfang;  Ni,Zhenhong;  Qi,Huabing;  Su,Nan;  Jin,Min;  Yang,Jing;  Tan,Qiaoyan;  Du,Xiaolan;  Chen,Bo;  Huang,Haiyang;  Chen,Shuai;  Yin,Liangjun;  Xu,Xiaoling;  Deng,Chuxia;  Luo,Lingfei;  Xie,Yangli;  Chen,Lin
Favorite | View/Download:1/0 | TC[WOS]:2 TC[Scopus]:3 | Submit date:2020/09/16
CARTILAGE-HAIR HYPOPLASIA  RMRP  SKELETAL DEVELOPMENT  WNT/Β-CATENIN  ZEBRAFISH  
Elevated Exogenous Pyruvate Potentiates Mesodermal Differentiation through Metabolic Modulation and AMPK/mTOR Pathway in Human Embryonic Stem Cells Journal article
STEM CELL REPORTS, 2019,Volume: 13,Issue: 2,Page: 338-351
Authors:  Chengcheng Song;  Faxiang Xu;  Zhili Ren;  Yumeng Zhang;  Ya Meng;  Yiqi Yang;  Shreyas Lingadahalli;  Edwin Cheung;  Gang Li;  Weiwei Liu;  Jianbo Wan;  Yang Zhao;  Guokai Chen
Favorite | View/Download:16/0 | TC[WOS]:1 TC[Scopus]:0 | Submit date:2020/04/22
Hescs  Pyruvate  Bmp4  Glycolysis  Tca Cycle  Ampk  Wnt  Metabolism  Mesoderm  Differentiation  
Development of functional dendrisomes based on a single molecule of polyesterbenzylether dendrimer and their application in cancer stem cell therapy Journal article
NPG ASIA MATERIALS, 2019,Volume: 11
Authors:  Li-Min Mu;  Lei Liu;  Rui Liu;  Jia-Lun Duan;  Shuang Ma;  Xue-Qi Li;  Yi-Nuo Cui;  Zhan-Bo Su;  Xiao Zhang;  Jian-Xing Hu;  Ying Xie;  Ying Zheng;  Wan-Liang Lu
Favorite | View/Download:11/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/04/08
Combined use of arginase and dichloroacetate exhibits anti-proliferative effects in triple negative breast cancer cells Journal article
JOURNAL OF PHARMACY AND PHARMACOLOGY, 2019,Volume: 71,Issue: 3,Page: 306-315
Authors:  Angela Verma;  Yau-Min Lam;  Yun-Chung Leung;  Xiaohui Hu;  Xin Chen;  Edwin Cheung;  Kin Yip Tam
Favorite | View/Download:16/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2020/05/21
Bacillus Caldovelox Arginase  Breast Cancer  Dichloroacetate  Drug Combination  Pegyated Human Arginase  
CBX6 is negatively regulated by EZH2 and plays a potential tumor suppressor role in breast cancer Journal article
SCIENTIFIC REPORTS, 2019,Volume: 9
Authors:  Houliang Deng;  Xiaowen Guan;  Longcai Gong;  Jianming Zeng;  Hongjie Zhang;  Mike Y. Chen;  Gang Li
Favorite | View/Download:4/0 | TC[WOS]:1 TC[Scopus]:0 | Submit date:2020/06/22
Astragalus Polysaccharide RAP Selectively Attenuates Paclitaxel-Induced Cytotoxicity Toward RAW 264.7 Cells by Reversing Cell Cycle Arrest and Apoptosis Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 9
Authors:  Bao, WR;  Li, ZP;  Zhang, QW;  Li, LF;  Liu, HB;  Ma, DL;  Leung, CH;  Lu, AP;  Bian, Z;  Han, QB
Favorite | View/Download:8/0 | TC[WOS]:1 TC[Scopus]:0 | Submit date:2020/03/24
Cell Cycle  Astragalus Polysaccharide  Cytotoxicity  Protective Effect  Apoptosis  
Structure-Based Discovery of a Selective KDM5A Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines Journal article
CANCERS, 2019,Volume: 11,Issue: 1
Authors:  Yang, GJ;  Ko, CN;  Zhong, HJ;  Leung, CH;  Ma, DL
Favorite | View/Download:10/0 | TC[WOS]:7 TC[Scopus]:0 | Submit date:2020/03/24
Cell Cycle Arrest  Kdm5a  Jumonji Domain  Histone Demethylation  Protein-protein Interaction  Virtual Screening  Breast Cancer  Cell Senescence  
Genetic Analysis of Candida auris Implicates Hsp90 in Morphogenesis and Azole Tolerance and Cdr1 in Azole Resistance Journal article
MBIO, 2019,Volume: 10,Issue: 1
Authors:  Sang Hu Kim;  Kali R. Iyer;  Lakhansing Pardeshi;  José F. Muñoz;  Nicole Robbins;  Christina A. Cuomo;  Koon Ho Wong;  Leah E. Cowen
Favorite | View/Download:11/0 | TC[WOS]:13 TC[Scopus]:0 | Submit date:2020/06/12
Antifungal Drug Resistance  Candida Albicans  Candida Auris  Cdr1  Developmental Program  Emerging Pathogen  Fungal Morphogenesis  Fungal Pathogen  Hsp90  Transcriptional Program  
Cyclin B1 stability is increased by interaction with BRCA1, and its overexpression suppresses the progression of BRCA1-associated mammary tumors Journal article
Experimental and Molecular Medicine, 2018,Volume: 50,Page: 136
Authors:  Choi, Eun Kyung;  Lim, Jeong-A;  Kim, Jong Kwang;  Jang, Moon Sun;  Kim, Sun Eui;  Baek, Hye Jung;  Park, Eun Jung;  Kim, Tae Hyun;  Deng, Chu-Xia;  Wang, Rui-Hong;  Kim, Sang Soo
Favorite | View/Download:25/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2018/10/30