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Hydroxyurea Facilitates Manifestation of Disease Relevant Phenotypes in Patients-Derived IPSCs-Based Modeling of Late-Onset Parkinson’s Disease Journal article
AGING AND DISEASE, 2019,Volume: 10,Issue: 5,Page: 1037-1048
Authors:  Yuan Tan;  Minjing Ke;  Zhijian Huang;  Cheong-Meng Chong;  Xiaotong Cen;  Jia-Hong Lu;  Xiaoli Yao;  Dajiang Qin;  Huanxing Su
Favorite | View/Download:16/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2020/04/08
Disease Phenotypes  Er Stress  Induced Pluripotentstem Cells  Parkinson’s Disease  Hydroxyurea  
Optimizing CRISPR/Cas9 technology for precise correction of the Fgfr3-G374R mutation in achondroplasia in mice Journal article
Journal of Biological Chemistry, 2019,Volume: 294,Issue: 4,Page: 1142-1151
Authors:  Miao,Kai;  Zhang,Xin;  Su,Sek Man;  Zeng,Jianming;  Huang,Zebin;  Chan,Un In;  Xu,Xiaoling;  Deng,Chu Xia
Favorite | View/Download:0/0 | TC[WOS]:4 TC[Scopus]:5 | Submit date:2020/09/16
ATP13A2 facilitates HDAC6 recruitment to lysosome to promote autophagosome–lysosome fusion Journal article
JOURNAL OF CELL BIOLOGY, 2019,Volume: 218,Issue: 1,Page: 267-284
Authors:  Ruoxi Wang;  Jieqiong Tan;  Tingting Chen;  Hailong Han;  Runyi Tian;  Ya Tan;  Yiming Wu;  Jingyi Cu;  Fang Chen;  Jie Li;  Lu Lv;  Xinjie Guan;  Shuai Shang;  Jiahong Lu;  Zhuohua Zhang
Favorite | View/Download:9/0 | TC[WOS]:11 TC[Scopus]:0 | Submit date:2020/04/14
SMAD signaling promotes melanoma metastasis independently of phenotype switching Journal article
Journal of Clinical Investigation, 2019,Volume: 129,Issue: 7,Page: 2702-2716
Authors:  Tuncer,Eylul;  Calçada,Raquel R.;  Zingg,Daniel;  Varum,Sandra;  Cheng,Phil;  Freiberger,Sandra N.;  Deng,Chu Xia;  Kleiter,Ingo;  Levesque,Mitchell P.;  Dummer,Reinhard;  Sommer,Lukas
Favorite | View/Download:0/0 | TC[WOS]:6 TC[Scopus]:7 | Submit date:2020/09/16
Optimizing CRISPR/Cas9 technology for precise correction of the Fgfr3-Gly374Arg mutation in achondroplasia in mice Journal article
The Journal of Biological Chemistry, 2018
Authors:  Kai Miao;  Xin Zhang;  Sek Man Su;  Jianming Zeng;  Zebin Huang;  Un In Chan;  Xiaoling Xu;  Chu-Xia Deng
Favorite | View/Download:27/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2018/12/17
Fgfr3  Crispr/cas9  Protein  Targeted Correction  Off-target  Achondroplasia  Dwarfism  Genome Editing  Gene Therapy  
Presenilin 1 deficiency suppresses autophagy in human neural stem cells through reducing γ-secretase-independent ERK/CREB signaling Journal article
CELL DEATH & DISEASE, 2018,Volume: 9,Page: 1-13
Authors:  Cheong-Meng Chong;  Minjing Ke;  Yuan Tan;  Zhijian Huang;  Ke Zhang;  Nana Ai;  Wei Ge;  Dajiang Qin;  Jia-Hong Lu;  Huanxing Su
Favorite | View/Download:36/0 | TC[WOS]:11 TC[Scopus]:0 | Submit date:2018/10/30
Dysbindin-1 Involvement in the Etiology of Schizophrenia Journal article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017,Volume: 18,Issue: 10
Authors:  Wang, Haitao;  Xu, Jiangping;  Lazarovici, Philip;  Zheng, Wenhua
Favorite | View/Download:15/0 | TC[WOS]:6 TC[Scopus]:0 | Submit date:2018/10/30
schizophrenia  dysbindin-1  susceptibility gene  neurotransmitter release  neurite outgrowth  
Arctigenin suppresses renal interstitial fibrosis in a rat model of obstructive nephropathy Journal article
PHYTOMEDICINE, 2017,Volume: 30,Page: 28-41
Authors:  Li, Ao;  Zhang, Xiaoxun;  Shu, Mao;  Wu, Mingjun;  Wang, Jun;  Zhang, Jingyao;  Wang, Rui;  Li, Peng;  Wang, Yitao
View | Adobe PDF | Favorite | View/Download:489/5 | TC[WOS]:17 TC[Scopus]:0 | Submit date:2018/10/30
Arctigenin  Renal Fibrosis  Inflammation  Transforming Growth Factor-beta 1  Oxidative Stress  Epithelial-mesenchymal Transition  
Mori Cortex regulates P-glycoprotein in Caco-2 cells and colons from rats with experimental colitis via direct and gut microbiota-mediated mechanisms Journal article
RSC ADVANCES, 2017,Volume: 7,Issue: 5,Page: 2594-2605
Authors:  Jing, Wanghui;  Gao, Xuejiao;  Han, Beilei;  Wei, Bin;  Hu, Nan;  Li, Sai;  Yan, Ru;  Wang, Yitao
View | Adobe PDF | Favorite | View/Download:521/10 | TC[WOS]:4 TC[Scopus]:0 | Submit date:2018/10/30
Vascular ADAM17 as a Novel Therapeutic Target in Mediating Cardiovascular Hypertrophy and Perivascular Fibrosis Induced by Angiotensin II Journal article
Hypertension, 2016,Volume: 68,Issue: 4,Page: 949-955
Authors:  Takayanagi T.;  Forrester S.J.;  Kawai T.;  Obama T.;  Tsuji T.;  Elliott K.J.;  Nuti E.;  Rossello A.;  Kwok H.F.;  Scalia R.;  Rizzo V.;  Eguchi S.
Favorite | View/Download:12/0 | TC[WOS]:27 TC[Scopus]:0 | Submit date:2018/12/19
End-organ Damage  Fibrosis  Hypertension  Renin Angiotensin System  Signal Transduction