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NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Miao,Kai;  Lei,Josh Haipeng;  Valecha,Monica Vishnu;  Zhang,Aiping;  Xu,Jun;  Wang,Lijian;  Lyu,Xueying;  Chen,Si;  Miao,Zhengqiang;  Zhang,Xin;  Su,Sek Man;  Shao,Fangyuan;  Rajendran,Barani Kumar;  Bao,Jiaolin;  Zeng,Jianming;  Sun,Heng;  Chen,Ping;  Tan,Kaeling;  Chen,Qiang;  Wong,Koon Ho;  Xu,Xiaoling;  Deng,Chu Xia
Favorite  |  View/Download:1/0  |  Submit date:2020/09/16
Nagilactone E suppresses TGF-β1-induced epithelial–mesenchymal transition, migration and invasion in non-small cell lung cancer cells Journal article
Phytomedicine, 2019,Volume: 52,Page: 32-39
Authors:  Zhang L.-L.;  Jiang X.-M.;  Huang M.-Y.;  Feng Z.-L.;  Chen X.;  Wang Y.;  Li H.;  Li A.;  Lin L.-G.;  Lu J.-J.
Favorite  |  View/Download:22/0  |  Submit date:2018/12/28
Epithelial-mesenchymal transition  Nagilactone E  Smad  TGF-β1  
Nagilactone E suppresses TGF-beta 1-induced epithelial-mesenchymal transition, migration and invasion in non-small cell lung cancer cells Journal article
PHYTOMEDICINE, 2019,Volume: 52,Page: 32-39
Authors:  Le-Le Zhang;  Xiao-Ming Jiang;  Mu-Yang Huang;  Zhe-Ling Feng;  Xiuping Chen;  Yitao Wang;  Hua Li;  Ao Li;  Li-Gen Lin;  Jin-Jian Lu
Favorite  |  View/Download:19/0  |  Submit date:2020/01/09
Nagilactone e  Tgf-β1  Epithelial-mesenchymal Transitio  Smad  
CtBP promotes metastasis of breast cancer through repressing cholesterol and activating TGF-beta signaling Journal article
ONCOGENE, 2018,Volume: 38,Issue: 12,Page: 2076-2091
Authors:  Zhiqiang Zhao;  Dapeng Hao;  Li Wang;  Jingjing Li;  Yuan Meng;  Peipei Li;  Yuan Wang;  Chao Zhang;  Haisheng Zhou;  Kevin Gardner;  Li-jun Di
Favorite  |  View/Download:12/0  |  Submit date:2020/05/21
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
View  |  Adobe PDF(2621Kb)  |  Favorite  |  View/Download:814/37  |  Submit date:2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
Effect of stromal cells in tumor microenvironment on metastasis initiation Journal article
International Journal of Biological Sciences, 2018,Volume: 14,Issue: 14,Page: 2083-2093
Authors:  Guo,Sen;  Deng,Chu Xia
Favorite  |  View/Download:1/0  |  Submit date:2020/09/16
Breast cancer  Metastasis initiation  Stromal cells  TME  
A comprehensive genomic meta-analysis identifies confirmatory role of OBSCN gene in breast tumorigenesis Journal article
ONCOTARGET, 2017,Volume: 8,Issue: 60,Page: 102263-102276
Authors:  Rajendran, Barani Kumar;  Deng, Chu-Xia
Favorite  |  View/Download:22/0  |  Submit date:2018/10/30
Breast Cancer  Obscn Gene  Obscurin  Cell Adhesion  Emt  
Up-regulation of CDK16 by multiple mechanisms in hepatocellular carcinoma promotes tumor progression Journal article
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2017,Volume: 36
Authors:  Wang, Yitao;  Qin, Xian;  Guo, Tao;  Liu, Pengpeng;  Wu, Ping;  Liu, Zhisu
Favorite  |  View/Download:6/0  |  Submit date:2018/11/01
Hepatocellular carcinoma (HCC)  Cyclin dependent Kinase 16 (CDK16)  Epithelial mesenchymal transition (EMT)  E2F1 transcription factor  miR-125b-5p  
Arctigenin suppresses renal interstitial fibrosis in a rat model of obstructive nephropathy Journal article
PHYTOMEDICINE, 2017,Volume: 30,Page: 28-41
Authors:  Li, Ao;  Zhang, Xiaoxun;  Shu, Mao;  Wu, Mingjun;  Wang, Jun;  Zhang, Jingyao;  Wang, Rui;  Li, Peng;  Wang, Yitao
View  |  Adobe PDF(6898Kb)  |  Favorite  |  View/Download:489/5  |  Submit date:2018/10/30
Arctigenin  Renal Fibrosis  Inflammation  Transforming Growth Factor-beta 1  Oxidative Stress  Epithelial-mesenchymal Transition  
Hypaconitine inhibits TGF-beta 1-induced epithelial-mesenchymal transition and suppresses adhesion, migration, and invasion of lung cancer A549 cells Journal article
CHINESE JOURNAL OF NATURAL MEDICINES, 2017,Volume: 15,Issue: 6,Page: 427-435
Authors:  Feng Hai-Tao;  Zhao Wen-Wen;  Lu Jin-Jian;  Wang Yi-Tao;  Chen Xiu-Ping
Favorite  |  View/Download:20/0  |  Submit date:2018/10/30
Emt  Hypaconitine  Tgf-beta 1  Nf-kappa b