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Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 10,Page: 1279-1291
Authors:  Lei Fan;  Xiao-xia Qiu;  Zhi-yuan Zhu;  Jian-lu Lv;  Jian Lu;  Fei Mao;  Jin Zhu;  Jia-ying Wang;  Xiao-wei Guan;  Jing Chen;  Jin Ren;  Ji-ming Ye;  Yong-hua Zhao;  Jian Li;  Xu Shen
Favorite | View/Download:15/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2020/04/14
App/ps1 Transgenic Mice  Alzheimer’s Disease  Autophagy  Inflammation  Nitazoxanide  
Resveratrol ameliorates endothelial dysfunction in diabetic and obese mice through sirtuin 1 and peroxisome proliferator-activated receptor δ Journal article
Pharmacological Research, 2019,Volume: 139,Page: 384-394
Authors:  Cheang W.S.;  Wong W.T.;  Wang L.;  Cheng C.K.;  Lau C.W.;  Ma R.C.W.;  Xu A.;  Wang N.;  Huang Y.;  Tian X.Y.
Favorite | View/Download:15/0 | TC[WOS]:7 TC[Scopus]:0 | Submit date:2019/01/15
Diet induced obesity  Endothelial dysfunction  PPARδ  SIRT1  
Benzofurans from Eupatorium chinense enhance insulin-stimulated glucose uptake in C2C12 myotubes and suppress inflammatory response in RAW264.7 macrophages Journal article
Fitoterapia, 2019,Volume: 134,Page: 346-354
Authors:  Jiang-HuanKe;  Li-ShaZhang;  Shi-XinChen;  Sheng-NanShen;  TianZhang;  Chang-XinZhou;  Jian-XiaMo;  Li-GenLin;  Li-SheGan
Favorite | View/Download:11/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2020/03/20
Glucose Uptake  Benzofuran  Eupatorium Chinense  Quantum Chemical Calculation  Anti-inflammation  
Anti-neuroinflammatory effects of SLOH in Aβ-induced BV-2 microglial cells and 3xTg-AD mice involve the inhibition of GSK-3β Journal article
Neuroscience Letters, 2018,Volume: 687,Page: 207-215
Authors:  Wu X.;  Kosaraju J.;  Tam K.Y.
Favorite | View/Download:2/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2018/12/18
3xTg-AD mice  BV-2 cells  GSK-3β  Neuroinflammation  SLOH  
Anti-neuroinflammatory effects of SLOH in A beta-induced BV-2 microglial cells and 3xTg-AD mice involve the inhibition of GSK-3 beta Journal article
NEUROSCIENCE LETTERS, 2018,Volume: 687,Page: 207-215
Authors:  Wu, Xiaoli;  Kosaraju, Jayasankar;  Tam, Kin Yip
Favorite | View/Download:12/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2019/01/17
SLOH  BV-2 cells  3xTg-AD mice  Neuroinflammation  GSK-3 beta  
GSK3-activated STAT5 regulates expression of SFRPs to modulate adipogenesis Journal article
FASEB JOURNAL, 2018,Volume: 32,Issue: 9,Page: 4714-4726
Authors:  Wang, Li;  Wang, Yuan;  Meng, Yuan;  Zhang, Chao;  Di, Lijun
Favorite | View/Download:1127/0 | TC[WOS]:8 TC[Scopus]:0 | Submit date:2018/10/30
Adipocyte Differentiation  Gsk3  Wnt Pathway  
Inhibiting Glycogen Synthase Kinase 3 Reverses Obesity-Induced White Adipose Tissue Inflammation by Regulating Apoptosis Inhibitor of Macrophage/CD5L-Mediated Macrophage Migration Journal article
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2018,Volume: 38,Issue: 9,Page: 2103-2116
Authors:  Wang, Li;  Wang, Yuan;  Zhang, Chao;  Li, Jingjing;  Meng, Yuan;  Dou, Man;  Noguchi, Constance Tom;  Di, Lijun
Favorite | View/Download:31/0 | TC[WOS]:5 TC[Scopus]:0 | Submit date:2018/10/30
Adipose Tissue  Gsk3  Inflammation  Macrophages  Obesity  
Presenilin 1 deficiency suppresses autophagy in human neural stem cells through reducing γ-secretase-independent ERK/CREB signaling Journal article
CELL DEATH & DISEASE, 2018,Volume: 9,Page: 1-13
Authors:  Cheong-Meng Chong;  Minjing Ke;  Yuan Tan;  Zhijian Huang;  Ke Zhang;  Nana Ai;  Wei Ge;  Dajiang Qin;  Jia-Hong Lu;  Huanxing Su
Favorite | View/Download:36/0 | TC[WOS]:11 TC[Scopus]:0 | Submit date:2018/10/30
Physalin B induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway Journal article
BIOMEDICINE & PHARMACOTHERAPY, 2018,Volume: 101,Page: 334-341
Authors:  Wang, Anqi;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Gan, Lishe;  Lin, Ligen
View | Adobe PDF | Favorite | View/Download:521/20 | TC[WOS]:9 TC[Scopus]:0 | Submit date:2018/10/30
Physalin b  Breast Cancer  Cell Cycle  Apoptosis  P53  Akt  
SLOH, a carbazole-based fluorophore, mitigates neuropathology and behavioral impairment in the triple-transgenic mouse model of Alzheimer's disease Journal article
NEUROPHARMACOLOGY, 2018,Volume: 131,Page: 351-363
Authors:  Wu, Xiaoli;  Kosaraju, Jayasankar;  Zhou, Wei;  Tam, Kin Yip
Favorite | View/Download:14/0 | TC[WOS]:4 TC[Scopus]:0 | Submit date:2018/10/31
Amyloid beta  Aggregation  Alzheimer's disease  3xTg-AD  Neuroprotection  SH-SY5Y