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Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 9,Page: 1193-1204
Authors:  Ting-ting Zhou;  Tong Zhao;  Fei Ma;  Yi-nan Zhang;  Jing Jiang;  Yuan Ruan;  Qiu-ying Yan;  Gai-hong Wang;  Jin Ren;  Xiao-wei Guan;  Jun Guo;  Yong-hua Zhao;  Ji-ming Ye;  Li-hong Hu;  Jing Chen;  Xu Shen
Favorite  |  View/Download:8/0  |  Submit date:2020/04/14
Type 2 Diabetes Mellitus  Hepatic Gluconeogenesis  Ampk Signaling Pathway  (e)-3-(2-(Quinoline-4-yl)Vinyl)-1h-indol-6-ol (Qvo)  4-[2-(1h-indol-3-yl)Vinyl]Quinoline (Ivq)  Prodrug  
A genome-wide siRNA screen to identify modulators of insulin sensitivity and gluconeogenesis Journal article
PLoS ONE, 2012,Volume: 7,Issue: 5
Authors:  Yang R.;  Lacson R.G.;  Castriota G.;  Zhang X.D.;  Liu Y.;  Zhao W.;  Einstein M.;  Camargo L.M.;  Qureshi S.;  Wong K.K.;  Zhang B.B.;  Ferrer M.;  Berger J.P.
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Hepatic-specific disruption of SIRT6 in mice results in fatty liver formation due to enhanced glycolysis and triglyceride synthesis Journal article
Cell Metabolism, 2010,Volume: 12,Issue: 3,Page: 224-236
Authors:  Kim H.-S.;  Xiao C.;  Wang R.-H.;  Lahusen T.;  Xu X.;  Vassilopoulos A.;  Vazquez-Ortiz G.;  Jeong W.-I.;  Park O.;  Ki S.H.;  Gao B.;  Deng C.-X.
Favorite  |  View/Download:6/0  |  Submit date:2018/12/13