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Effects of dextran sulfate sodium induced experimental colitis on cytochrome P450 activities in rat liver, kidney and intestine Journal article
CHEMICO-BIOLOGICAL INTERACTIONS, 2017,Volume: 271,Page: 48-58
Authors:  Hu, Nan;  Huang, Yanjuan;  Gao, Xuejiao;  Li, Sai;  Yan, Zhixiang;  Wei, Bin;  Yan, Ru
Favorite  |  View/Download:19/0  |  Submit date:2018/10/30
Experimental Colitis  Dextran Sulfate Sodium  Cyps  Rat Liver Microsomes  Rat Renal Microsomes  Rat Intestinal Microsomes  
Regulatory mechanisms of gut microbiota on intestinal CYP3A and P-glycoprotein in rats with dextran sulfate sodium-induced colitis Journal article
Yaoxue Xuebao, 2017,Volume: 52,Issue: 1,Page: 34-43
Authors:  Gao X.-J.;  Li T.;  Wei B.;  Yan Z.-X.;  Yan R.
Favorite  |  View/Download:7/0  |  Submit date:2018/12/28
Fecal microbiota transplantation  Gut dysbiosis  Intestinal cytochrome P450 3A  Intestinal P-glycoprotein  Outer membrane vesicles  Toll like receptor 4  
Metabolic characterization of (±)-praeruptorin A in vitro and in vivo by high performance liquid chromatography coupled with hybrid triple quadrupole-linear ion trap mass spectrometry and time-of-flight mass spectrometry Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2014,Volume: 90,Issue: 5,Page: 98-110
Authors:  Song, Yue-Lin;  Jing, Wang-Hui;  Yan, Ru;  Wang, Yi-Tao
View  |  Adobe PDF(3404Kb)  |  Favorite  |  View/Download:453/8  |  Submit date:2018/11/01
(+/-)-praeruptorin a  Metabolism  Lightsight (Tm) Software  In Vivo  Peucedani Radix  
Simultaneously enantiospecific determination of (+)-trans-khellactone, (+/-)-praeruptorin A, (+/-)-praeruptorin B, (+)-praeruptorin E, and their metabolites, (+/-)-cis-khellactone, in rat plasma using Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2014,Volume: 88,Issue: 1,Page: 269-277
Authors:  Song, Yuelin;  Jing, Wanghui;  Yang, Fengqing;  Shi, Zhan;  Yao, Meicun;  Yan, Ru;  Wang, Yitao
View  |  Adobe PDF(488Kb)  |  Favorite  |  View/Download:542/58  |  Submit date:2018/11/01
Online Spe  Chiral Lc-ms/ms  Enantiospecific  Peucedani Radix  Pharmacokinetics  
Regulation of human pregnane X receptor and its target gene cytochrome P450 3A by praeruptorin a isolated from the herbal medicine peucedanum praeruptorum Journal article
Planta Medica, 2013,Volume: 79,Issue: 16,Page: 1509-1515
Authors:  Huang L.;  Bi H.-C.;  Li Y.-H.;  Zhang J.-Q.;  Kuang S.-Y.;  Zhang L.;  Wang Y.-T.;  Huang M.
Favorite  |  View/Download:12/0  |  Submit date:2018/11/06
Apiaceae  Cytochrome P450 3a  Herb-drug Interaction  Peucedanum Praeruptorum  Praeruptorin a  Pregnane x Receptor  
Identification of cytochrome P450 isoenzymes involved in metabolism of (+)-praeruptorin A, a calcium channel blocker, by human liver microsomes using ultra high-performance liquid chromatography coupl Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2013,Volume: 77,Page: 175-188
Authors:  Jing, Wang-Hui;  Song, Yue-Lin;  Yan, Ru;  Wang, Yi-Tao
Favorite  |  View/Download:17/0  |  Submit date:2018/11/01
Angular-type Pyranocoumarins  (+)-praeruptorin a  Uhplc-qt-ms/ms  Human Liver Microsomes  Cyp 3a4  
Enzyme kinetic and molecular docking studies for the inhibitions of miltirone on major human cytochrome P450 isozymes Journal article
Phytomedicine, 2013,Volume: 20,Issue: 2018-03-04,Page: 367
Authors:  Zhou X.;  Wang Y.;  Hu T.;  Or P.M.Y.;  Wong J.;  Kwan Y.W.;  Wan D.C.C.;  Hoi P.M.;  Lai P.B.S.;  Yeung J.H.K.
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Cytochrome P450  Miltirone  Molecular Docking  Probe Substrates  Salvia Miltiorrhiza  
Identification of cytochrome P450 isoenzymes involved in metabolism of (+)-praeruptorin A, a calcium channel blocker, by human liver microsomes using ultra high-performance liquid chromatography coupled with tandem mass spectrometry Journal article
Journal of Pharmaceutical and Biomedical Analysis, 2013,Volume: 77,Page: 175
Authors:  Jing W.-H.;  Song Y.-L.;  Yan R.;  Wang Y.-T.
Favorite  |  View/Download:3/0  |  Submit date:2018/10/31
(+)-praeruptorin a  Angular-type Pyranocoumarins  Cyp 3a4  Human Liver Microsomes  Uhplc-qt-ms/ms  
Up-regulatation of CYP3A expression through pregnent X receptor by praeruptorin D isolated from Peucedanum praeruptorum Dunn Journal article
Journal of Ethnopharmacology, 2013,Volume: 148,Issue: 2,Page: 596
Authors:  Huang L.;  Huang M.;  Li Y.-H.;  Li R.-M.;  Zeng Y.;  Kuang S.-Y.;  Zhang L.;  Wang Y.-T.;  Bi H.-C.
Favorite  |  View/Download:12/0  |  Submit date:2018/10/30
Praeruptorin d Pregnane x Receptor (Pxr) Cytochrome P450 3a Induction Herb-drug Interaction  
Anti-cancer properties of terpenoids isolated from Rhizoma Curcumae - A review Journal article
JOURNAL OF ETHNOPHARMACOLOGY, 2012,Volume: 143,Issue: 2,Page: 406-411
Authors:  Lu, JJ (Lu, Jin-Jian);  Dang, YY (Dang, Yuan-Ye);  Huang, M (Huang, Min);  Xu, WS (Xu, Wen-Shan);  Chen, XP (Chen, Xiu-Ping);  Wang, YT (Wang, Yi-Tao)
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Cell-cycle Arrest  Chromatography-mass-spectrometry  Human Lung-carcinoma  Breast-cancer Cells  Beta-elemene  Delta-elemene  In-vitro  D-galactosamine/lipopolysaccharide  Inhibitory-activity  Glioblastoma Cells