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Combined transcriptomic and proteomic analysis reveals a diversity of venom-related and toxin-like peptides expressed in the mat anemone Zoanthus natalensis (Cnidaria, Hexacorallia) Journal article
ARCHIVES OF TOXICOLOGY, 2019,Volume: 93,Issue: 6,Page: 1745-1767
Authors:  Qiwen Liao;  Guiyi Gong;  Terence C. W. Poon;  Irene L. Ang;  Kate M. K. Lei;  Shirley Weng In Siu;  Clarence Tsun Ting Wong;  Gandhi Rádis-Baptista;  Simon Ming-Yuen Lee
Favorite | View/Download:226/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/01/16
Cnidaria  Neuroprotection  Proteomic  Transcriptomic  Venom-derived Peptide  Zoantharian  
Pinostrobin Exerts Neuroprotective Actions in Neurotoxin-Induced Parkinson's Disease Models through Nrf2 Induction Journal article
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2018,Volume: 66,Issue: 31,Page: 8307-8318
Authors:  Li, Chuwen;  Tang, Benqin;  Feng, Yu;  Tang, Fan;  Hoi, Maggie Pui-Man;  Su, Ziren;  Lee, Simon Ming-Yuen
Favorite | View/Download:18/0 | TC[WOS]:11 TC[Scopus]:0 | Submit date:2018/10/31
Pinostrobin  Parkinson's Disease  Neurotoxin  Nrf2  
A novel Ca2+ current blocker promotes angiogenesis and cardiac healing after experimental myocardial infarction in mice Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 134,Page: 109-117
Authors:  Cui, Guozhen;  Xin, Qiqi;  Tseng, Hisa Hui Ling;  Hoi, Maggie PuiMan;  Wang, Yan;  Yang, Binrui;  Choi, InLeng;  Wang, Yuqiang;  Yuan, Rong;  Chen, Keji;  Cong, Weihong;  Lee, Simon MingYuen
View | Adobe PDF | Favorite | View/Download:503/15 | TC[WOS]:4 TC[Scopus]:0 | Submit date:2018/10/30
Cardioprotection  Angiogenesis  ADTM  Zebrafish  VEGF  
Novel Kunitz-like Peptides Discovered in the Zoanthid Palythoa caribaeorum through Transcriptome Sequencing Journal article
JOURNAL OF PROTEOME RESEARCH, 2018,Volume: 17,Issue: 2,Page: 891-902
Authors:  Liao, Qiwen;  Li, Shengnan;  Siu, Shirley Weng In;  Yang, Binrui;  Huang, Chen;  Chan, Judy Yuet-Wa;  Morlighem, Jean-Etienne R. L.;  Wong, Clarence Tsun Ting;  Radis-Baptista, Gandhi;  Lee, Simon Ming-Yuen
Favorite | View/Download:26/0 | TC[WOS]:5 TC[Scopus]:0 | Submit date:2018/10/30
Soft Coral  Transcriptome  Kunitz-like Peptides  Protein Docking Zebrafish  Neurotoxin  Zoanthids  
Schisantherin A protects against 6-OHDA-induced dopaminergic neuron damage in zebrafish and cytotoxicity in SH-SY5Y cells through the ROS/NO and AKT/GSK3 β pathways Journal article
JOURNAL OF ETHNOPHARMACOLOGY, 2015,Volume: 170,Page: 8-15
Authors:  Lun Qing Zhang;  Fei Sa;  Cheong Meng Chong;  Ying Wang;  Zhong Yan Zhou;  Raymond Chuen Chung Chang;  Shun Wan Chan;  Pui Man Hoi;  Simon Ming Yuen Lee
Favorite | View/Download:4/0 | TC[WOS]:23 TC[Scopus]:0 | Submit date:2020/04/15
6-hydroxydopamine (6-ohda)  Oxidative Stress  Parkinson׳s Disease  Schisantherin a  
Supramolecular Inhibition of Neurodegeneration by a Synthetic Receptor Journal article
ACS Medicinal Chemistry Letters, 2015,Volume: 6,Issue: 12,Page: 1174
Authors:  Shengke Li;  Huanxian Chen;  Xue Yang;  David Bardelang;  Ian W. Wyman;  Jianbo Wan;  Simon M. Y. Lee;  Ruibing Wang
Favorite | View/Download:8/0 | TC[WOS]:28 TC[Scopus]:0 | Submit date:2018/10/30
Cucurbituril  Inhibition  Neurodegeneration  Neurotoxin  Supramolecular Complexation  
The Novel Tetramethylpyrazine Bis-nitrone (TN-2) Protects Against MPTP/MPP+-Induced Neurotoxicity via Inhibition of Mitochondrial-Dependent Apoptosis Journal article
JOURNAL OF NEUROIMMUNE PHARMACOLOGY, 2014,Volume: 9,Issue: 2,Page: 245-258
Authors:  Xu, DP;  Duan, HW;  Zhang, ZJ;  Cui, W;  Wang, L;  Sun, YW;  Lang, M;  Hoi, PM;  Han, YF;  Wang, YQ;  Lee, SM
Favorite | View/Download:5/0 | TC[WOS]:21 TC[Scopus]:0 | Submit date:2020/04/15
Mitochondrial-dependent Apoptosis  Parkinson’s Disease  Mptp  Dopaminergic Neuron  
Danshensu protects against 6-hydroxydopamine-induced damage of PC12 cells in vitro and dopaminergic neurons in zebrafish Journal article
Neuroscience Letters, 2013,Volume: 543,Page: 121-125
Authors:  Chong C.-M.;  Zhou Z.-Y.;  Razmovski-Naumovski V.;  Cui G.-Z.;  Zhang L.-Q.;  Sa F.;  Hoi P.-M.;  Chan K.;  Lee S.M.Y.
Favorite | View/Download:12/0 | TC[WOS]:49 TC[Scopus]:0 | Submit date:2018/11/06
6-ohda  Neurodegeneration  Ros  Zebrafish  
Quercetin exerts a neuroprotective effect through inhibition of the iNOS/NO system and pro-inflammation gene expression in PC12 cells and in zebrafish Journal article
International Journal of Molecular Medicine, 2011,Volume: 27,Issue: 2,Page: 195
Authors:  Zhang Z.J.;  Cheang L.C.V.;  Wang M.W.;  Lee S.M.-Y.
Favorite | View/Download:7/0 | TC[WOS]:91 TC[Scopus]:0 | Submit date:2018/10/30
Neuroprotection  Parkinson's Disease  Quercetin  Zebrafish  
Isolation of scorpion (Androctonus amoreuxi) putative alpha neurotoxins and parallel cloning of their respective cDNAs from a single sample of venom Journal article
Regulatory Peptides, 2003,Volume: 115,Issue: 2,Page: 115-121
Authors:  Chen T.;  Folan R.;  Kwok H.;  O'Kane E.J.;  Bjourson A.J.;  Shaw C.
Favorite | View/Download:4/0 | TC[WOS]:13 TC[Scopus]:0 | Submit date:2018/12/19
Cdna Cloning  Neurotoxin  Precursor  Scorpion  Venom