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Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 10,Page: 1279-1291
Authors:  Lei Fan;  Xiao-xia Qiu;  Zhi-yuan Zhu;  Jian-lu Lv;  Jian Lu;  Fei Mao;  Jin Zhu;  Jia-ying Wang;  Xiao-wei Guan;  Jing Chen;  Jin Ren;  Ji-ming Ye;  Yong-hua Zhao;  Jian Li;  Xu Shen
Favorite  |  View/Download：14/0  |  Submit date：2020/04/14
App/ps1 Transgenic Mice  Alzheimer’s Disease  Autophagy  Inflammation  Nitazoxanide  
Anti-inflammatory activities of Sigesbeckia glabrescens Makino: combined in vitro and in silico investigations Journal article
CHINESE MEDICINE, 2019,Volume: 14,Issue: 1
Authors:  Zhangfeng Zhong;  Qianru Zhang;  Hongxun Tao;  Wei Sang;  Liao Cui;  Wenan Qiang;  Wai San Cheang;  Yuanjia Hu;  Hua Yu;  Yitao Wang
Favorite  |  View/Download：63/0  |  Submit date：2019/11/22
Sigesbeckia Glabrescens Makino  Infammation  Lipopolysaccharide  Docking  Tlr4  Nf-κb  
Deciphering the Pharmacological Mechanisms of the Huayu-Qiangshen-Tongbi Formula Through Integrating Network Pharmacology and In Vitro Pharmacological Investigation Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:  Zihao Wang;  Ke-Gang Linghu;  Yuanjia Hu;  Huali Zuo;  Hao Yi;  Shi-Hang Xiong;  Jinjian Lu;  Ging Chan;  Hua Yu;  Run-Yue Huang
Favorite  |  View/Download：16/0  |  Submit date：2019/12/04
Rheumatoid Arthritis  Network Pharmacology  Traditional Chinese Medicine  Huayu-qiangshen-tongbi Formula  In Vitro Validation  
Therapeutic Potential of Pien-Tze-Huang: A Review on Its Chemical Composition, Pharmacology, and Clinical Application Journal article
Molecules, 2019,Volume: 24,Issue: 18
Authors:  Lili Huang;  Yiping Zhang;  Xiaoqin Zhang;  Xiuping Chen;  Yitao Wang;  Jinjian Lu;  Mingqing Huang
Favorite  |  View/Download：11/0  |  Submit date：2020/03/27
Pien-tze-huang  Chemical Composition  Pharmacology  Clinical Application  Cancer  
Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 9,Page: 1193-1204
Authors:  Ting-ting Zhou;  Tong Zhao;  Fei Ma;  Yi-nan Zhang;  Jing Jiang;  Yuan Ruan;  Qiu-ying Yan;  Gai-hong Wang;  Jin Ren;  Xiao-wei Guan;  Jun Guo;  Yong-hua Zhao;  Ji-ming Ye;  Li-hong Hu;  Jing Chen;  Xu Shen
Favorite  |  View/Download：8/0  |  Submit date：2020/04/14
Type 2 Diabetes Mellitus  Hepatic Gluconeogenesis  Ampk Signaling Pathway  (e)-3-(2-(Quinoline-4-yl)Vinyl)-1h-indol-6-ol (Qvo)  4-[2-(1h-indol-3-yl)Vinyl]Quinoline (Ivq)  Prodrug  
Rhodiolaspecies: A comprehensive review oftraditional use, phytochemistry, pharmacology,toxicity, and clinical study Journal article
MEDICINAL RESEARCH REVIEWS, 2019,Volume: 39,Issue: 5,Page: 1779-1850
Authors:  Hongxun Tao;  Xu Wu;  Jiliang Cao;  Yu Peng;  Anqi Wang;  Jin Pei;  Jianbo Xiao;  Shengpeng Wang;  Yitao Wang
Favorite  |  View/Download：7/0  |  Submit date：2020/05/06
Bioactivity  Chemical Constituents  Rhodiola Species  Toxicology  Traditional Use  
Molecular Interactions for the Curcumin-Polymer Complex with Enhanced Anti-Inflammatory Effects Journal article
PHARMACEUTICS, 2019,Volume: 11,Issue: 9
Authors:  Yan He;  Hongfei Liu;  Wangqing Bian;  Yue Liu;  Xinyang Liu;  Shijing Ma;  Xi Zheng;  Zhiyun Du;  Kun Zhang;  Defang Ouyang
Favorite  |  View/Download：8/0  |  Submit date：2020/03/25
Curcumin  Polyvinylpyrrolidone (Pvp)  Solid Dispersions  Molecular Modeling  Drug-polymer Interactions  
Development of a Liposomal Formulation of Acetyltanshinone IIA for Breast Cancer Therapy Journal article
MOLECULAR PHARMACEUTICS, 2019,Volume: 16,Issue: 9,Page: 3873-3886
Authors:  Qi Wang;  Man Luo;  Na We;  Alex Chang;  Kathy Qian Luo
Favorite  |  View/Download：36/0  |  Submit date：2020/05/12
Anti-breast Cancer Drugs  Acetyltanshinone Iia (Ata)  Mpeg-liposomes  Bioavailabilit  Pharmacokinetics  Toxicity Study  
An open-label randomised comparison of aripiprazole, olanzapine and risperidone for the acute treatment of first-episode schizophrenia: Eight-week outcomes Journal article
JOURNAL OF PSYCHOPHARMACOLOGY, 2019,Volume: 33,Issue: 10,Page: 1227-1236
Authors:  Zhang Cheng;  Yanbo Yuan;  Xue Han;  Shangli Cai;  Fude Yang;  Zheng Lu;  Chuanyue Wang;  Hong Deng;  Jingping Zhao;  Yutao Xiang;  Christoph U Correll;  Xin Yu
Favorite  |  View/Download：4/0  |  Submit date：2020/05/26
First-episode  Schizophrenia  Antipsychotic  Efficacy  Safety  
Insight into the Dissolution Molecular Mechanism of Ternary Solid Dispersions by Combined Experiments and Molecular Simulations Journal article
AAPS PHARMSCITECH, 2019,Volume: 20,Issue: 7
Authors:  Run Han;  Tianhe Huang;  Xinyang Liu;  Xinyang Liu;  Haifeng Li;  Jiahong Lu;  Yuanhui Ji;  Huimin Sun;  Defang Ouyang
Favorite  |  View/Download：7/0  |  Submit date：2020/03/25
Solid Dispersion  Dissolution Effect  Molecular Modeling  Ternary System