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Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells Journal article
Acta Pharmaceutica Sinica B, 2020,Volume: 10,Issue: 4,Page: 615-627
Authors:  Zhang,Baoyuan;  Lyu,Junfang;  Yang,Eun Ju;  Liu,Yifan;  Wu,Changjie;  Pardeshi,Lakhansing;  Tan,Kaeling;  Chen,Qiang;  Xu,Xiaoling;  Deng,Chu Xia;  Shim,Joong Sup
Favorite  |  View/Download:0/0  |  Submit date:2020/09/16
BRCA1  Breast cancer  DNA damage  HDAC  Histone deacetylase  Reactive oxygen species  Synthetic lethality  
Metformin protects PC12 cells and hippocampal neurons from H2O (2)-induced oxidative damage through activation of AMPK pathway Journal article
JOURNAL OF CELLULAR PHYSIOLOGY, 2019,Volume: 234,Issue: 9,Page: 16619-16629
Authors:  Xia Zhao;  Zhiwen Zeng;  Uma Gaur;  Jiankang Fang;  Tangming Peng;  Shuai Li;  Wenhua Zheng
Favorite  |  View/Download:8/0  |  Submit date:2020/06/11
Aging  Amp-activated Protein Kinase  Hydrogen Peroxide  Metformin  Pc12 Cells  
SIRT3 promotes antimycobacterial defenses by coordinating mitochondrial and autophagic functions Journal article
Autophagy, 2019,Volume: 15,Issue: 8,Page: 1356-1375
Authors:  Kim,Tae Sung;  Jin,Yeung Bae;  Kim,Yi Sak;  Kim,Sup;  Kim,Jin Kyung;  Lee,Hye Mi;  Suh,Hyun Woo;  Choe,Jin Ho;  Kim,Young Jae;  Koo,Bon Sang;  Kim,Han Na;  Jung,Mingyu;  Lee,Sang Hee;  Kim,Don Kyu;  Chung,Chaeuk;  Son,Ji Woong;  Min,Jung Joon;  Kim,Jin Man;  Deng,Chu Xia;  Kim,Hyun Seok;  Lee,Sang Rae;  Jo,Eun Kyeong
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autophagy  mitochondrial homeostasis  Mycobacterium tuberculosis  PPARA  SIRT3  
Fighting Liver Fibrosis with Naturally Occurring Antioxidants Journal article
PLANTA MEDICA, 2018,Volume: 84,Issue: 18,Page: 1318-1333
Authors:  Lin, Ligen;  Zhou, Fayang;  Shen, Shengnan;  Zhang, Tian
Favorite  |  View/Download:12/0  |  Submit date:2019/01/17
Liver Fibrosis  Antioxidants  Oxidative Stress  Reactive Oxygen Species  Hepatic Stellate Cells  Natural Products  
MnSOD mediates shear stress-promoted tumor cell migration and adhesion Journal article
FREE RADICAL BIOLOGY AND MEDICINE, 2018,Volume: 129,Page: 46-58
Authors:  Ma, Shijun;  Fu, Afu;  Lim, Sierin;  Chiew, Geraldine Giap Ying;  Luo, Kathy Qian
Favorite  |  View/Download:12/0  |  Submit date:2019/01/17
Shear stress  Tumor cell adhesion  Tumor cell migration  Reactive oxygen species  MnSOD  FAK  
Fluidic shear stress increases the anti-cancer effects of ROS-generating drugs in circulating tumor cells Journal article
BREAST CANCER RESEARCH AND TREATMENT, 2018,Volume: 172,Issue: 2,Page: 297-312
Authors:  Regmi S;  Fung TS;  Lim S;  Luo KQ
Favorite  |  View/Download:18/0  |  Submit date:2018/10/30
Circulating Tumor Cells  Shear Stress  Reactive Oxygen Species  Apoptosis  Anti-cancer Drugs  Doxorubicin  
Serum amyloid A promotes LPS clearance and suppresses LPS-induced inflammation and tissue injury Journal article
EMBO REPORTS, 2018,Volume: 19,Issue: 10
Authors:  Cheng, Ni;  Liang, Yurong;  Du, Xiaoping;  Ye, Richard D.
View  |  Adobe PDF(2278Kb)  |  Favorite  |  View/Download:544/16  |  Submit date:2018/10/30
acute-phase response  inflammation  innate immunity  lipopolysaccharide  serum amyloid A  
Honokiol protects hepatocytes from oxidative injury through mitochondrial deacetylase SIRT3 Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 834,Page: 176-187
Authors:  Liu, Jing-Xin;  Shen, Sheng-Nan;  Tong, Qiang;  Wang, Yi-Tao;  Lin, Li-Gen
Favorite  |  View/Download:45/0  |  Submit date:2018/10/30
Honokiol  Oxidative Stress  Liver  Sirt3  Mitochondria  Fragmentation  
Gallic acid, a natural polyphenol, protects against tert-butyl hydroperoxide- induced hepatotoxicity by activating ERK-Nrf2-Keap1-mediated antioxidative response Journal article
Food and Chemical Toxicology, 2018,Volume: 119,Page: 479-488
Authors:  Feng R.-B.;  Wang Y.;  He C.;  Yang Y.;  Wan J.-B.
Favorite  |  View/Download:6/0  |  Submit date:2018/12/28
Gallic Acid  Nuclear Factor Erythroid 2-related Factor 2  Oxidative Stress  Tert-butyl Hydroperoxide  
MK2 mediates macrophage activation and acute lung injury by regulating let-7e miRNA Journal article
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2018,Volume: 315,Issue: 3,Page: L371-L381
Authors:  Wu, Yaxian;  He, Huiqiong;  Ding, Yunhe;  Liu, Sirui;  Zhang, Depeng;  Wang, Jun;  Jiang, Hongchao;  Zhang, Dan;  Sun, Lei;  Ye, Richard D.;  Qian, Feng
View  |  Adobe PDF(2092Kb)  |  Favorite  |  View/Download:501/18  |  Submit date:2018/10/30
acute lung injury  let-7e  lipopolysaccharides  macrophage  MAPK-activated protein kinase 2  miRNA  MK2