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The metabolic footprint during adipocyte commitment highlights ceramide modulation as an adequate approach for obesity treatment Journal article
EBioMedicine, 2020,Volume: 51
Authors:  Hou,Weilong;  Chen,Qiang;  Wang,Haitao;  Qiu,Pengxiang;  Lyu,Xueying;  Chen,Weiping;  Chua,Melvin L.K.;  Chinn,Y. Eugene;  Deng,Chu Xia;  Wang,Ruihong
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Adipogenesis  Apoptosis  Ceramide  Epigenetic modification  Metabolic landscape  Metabolomics  Obesity  
Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism Journal article
Cell Metabolism, 2019,Volume: 30,Issue: 2,Page: 385-401.e9
Authors:  Collin de l'Hortet,Alexandra;  Takeishi,Kazuki;  Guzman-Lepe,J.;  Morita,Kazutoyo;  Achreja,Abhinav;  Popovic,Branimir;  Wang,Yang;  Handa,Kan;  Mittal,Anjali;  Meurs,Noah;  Zhu,Z.;  Weinberg,F.;  Salomon,Michael;  Fox,I. J.;  Deng,Chu Xia;  Nagrath,Deepak;  Soto-Gutierrez,Alejandro
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cellular engineering  hepatic differentiation  human fatty liver  human iPSCs  liver metabolism  NAFLD  NASH  SIRT1  
Myricanol rescues dexamethasone‐induced muscle dysfunction via a sirtuin 1‐dependent mechanism Journal article
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2019,Volume: 10,Issue: 2,Page: 429-444
Authors:  Shengnan Shen;  Qiwen Liao;  Jingxin Liu;  Ruile Pan;  Simon Ming-Yuen Lee;  Ligen Lin1
Favorite  |  View/Download:6/0  |  Submit date:2020/05/07
Autophagy  Dexamethasone  Muscle Atrophy  Myricanol  Pgc-1α  Sirt1  
Resveratrol ameliorates endothelial dysfunction in diabetic and obese mice through sirtuin 1 and peroxisome proliferator-activated receptor δ Journal article
Pharmacological Research, 2019,Volume: 139,Page: 384-394
Authors:  Cheang W.S.;  Wong W.T.;  Wang L.;  Cheng C.K.;  Lau C.W.;  Ma R.C.W.;  Xu A.;  Wang N.;  Huang Y.;  Tian X.Y.
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Diet induced obesity  Endothelial dysfunction  PPARδ  SIRT1  
Myricanol rescues dexamethasone-induced muscle dysfunction via a sirtuin 1-dependent mechanism Journal article
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2019,Volume: 10,Issue: 2,Page: 429-444
Authors:  Shen, SN;  Liao, QW;  Liu, JX;  Pan, RL;  Lee, SMY;  Lin, LG
Favorite  |  View/Download:227/0  |  Submit date:2020/01/16
Autophagy  Myricanol  Sirt1  Dexamethasone  Muscle Atrophy  Pgc-1 Alpha  
Resveratrol ameliorates endothelial dysfunction in diabetic and obese mice through sirtuin 1 and peroxisome proliferator-activated receptor delta Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 139,Page: 384-394
Authors:  Wai San Cheang;  Wing Tak Wong;  Li Wang;  Chak Kwong Cheng;  Chi Wai Lau;  Ronald Chin Wan Ma;  Aimin Xu;  Nanping Wang;  Yu Huang;  Xiao Yu Tian
Favorite  |  View/Download:13/0  |  Submit date:2020/04/09
Pparδ  Sirt1  Endothelial Dysfunction  Diet Induced Obesity  
BRCA1 function in the intra-S checkpoint is activated by acetylation via a pCAF/SIRT1 axis Journal article
ONCOGENE, 2018,Volume: 37,Issue: 17,Page: 2343-2350
Authors:  Lahusen, Tyler J.;  Kim, Seung-Jin;  Miao, Kai;  Huang, Zebin;  Xu, Xiaoling;  Deng, Chu-Xia
Favorite  |  View/Download:29/0  |  Submit date:2018/10/30
BRCA1 function in the intra-S checkpoint is activated by acetylation via a pCAF/SIRT1 axis Journal article
Oncogene, 2018,Volume: 37,Issue: 17,Page: 2343-2350
Authors:  Lahusen,Tyler J.;  Kim,Seung Jin;  Miao,Kai;  Huang,Zebin;  Xu,Xiaoling;  Deng,Chu Xia
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γ-Mangostin, a xanthone from mangosteen, attenuates oxidative injury in liver via NRF2 and SIRT1 induction Journal article
Journal of Functional Foods, 2018,Volume: 40,Page: 544-553
Authors:  Wang A.;  Li D.;  Wang S.;  Zhou F.;  Li P.;  Wang Y.;  Lin L.
Favorite  |  View/Download:12/0  |  Submit date:2018/10/31
Γ-mangostin  Mangosteen  Liver Oxidative Injury  Nrf2  Sirt1  Pgc-1α  
gamma-Mangostin, a xanthone from mangosteen, attenuates oxidative injury in liver via NRF2 and SIRT1 induction Journal article
JOURNAL OF FUNCTIONAL FOODS, 2018,Volume: 40,Page: 544-553
Authors:  Wang, Anqi;  Li, Dan;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Lin, Ligen
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Gamma-mangostin  Mangosteen  Liver Oxidative Injury  Nrf2  Sirt1  Pgc-1 Alpha