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NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Miao,Kai;  Lei,Josh Haipeng;  Valecha,Monica Vishnu;  Zhang,Aiping;  Xu,Jun;  Wang,Lijian;  Lyu,Xueying;  Chen,Si;  Miao,Zhengqiang;  Zhang,Xin;  Su,Sek Man;  Shao,Fangyuan;  Rajendran,Barani Kumar;  Bao,Jiaolin;  Zeng,Jianming;  Sun,Heng;  Chen,Ping;  Tan,Kaeling;  Chen,Qiang;  Wong,Koon Ho;  Xu,Xiaoling;  Deng,Chu Xia
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Combined use of arginase and dichloroacetate exhibits anti-proliferative effects in triple negative breast cancer cells Journal article
JOURNAL OF PHARMACY AND PHARMACOLOGY, 2019,Volume: 71,Issue: 3,Page: 306-315
Authors:  Angela Verma;  Yau-Min Lam;  Yun-Chung Leung;  Xiaohui Hu;  Xin Chen;  Edwin Cheung;  Kin Yip Tam
Favorite  |  View/Download:16/0  |  Submit date:2020/05/21
Bacillus Caldovelox Arginase  Breast Cancer  Dichloroacetate  Drug Combination  Pegyated Human Arginase  
Selective Inhibition of Lysine-Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple-Negative Breast Cancer Therapy Journal article
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018,Volume: 57,Issue: 40,Page: 13091-13095
Authors:  Yang, Guan-Jun;  Wang, Wanhe;  Mok, Simon Wing Fai;  Wu, Chun;  Law, Betty Yuen Kwan;  Miao, Xiang-Min;  Wu, Ke-Jia;  Zhong, Hai-Jing;  Wong, Chun-Yuen;  Wong, Vincent Kam Wai;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite  |  View/Download:39/0  |  Submit date:2018/10/30
Drug Discovery  Epigenetics  Medicinal Chemistry  Triple-negative Breast Cancer  
Physalin B induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway Journal article
BIOMEDICINE & PHARMACOTHERAPY, 2018,Volume: 101,Page: 334-341
Authors:  Wang, Anqi;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Gan, Lishe;  Lin, Ligen
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Physalin b  Breast Cancer  Cell Cycle  Apoptosis  P53  Akt  
Identification of a rhodium(III) complex as a Wee1 inhibitor against TP53-mutated triple-negative breast cancer cells Journal article
CHEMICAL COMMUNICATIONS, 2018,Volume: 54,Issue: 20,Page: 2463-2466
Authors:  Yang, Guan-Jun;  Zhong, Hai-Jing;  Ko, Chung-Nga;  Wong, Suk-Yu;  Vellaisamy, Kasipandi;  Ye, Min;  Ma, Dik-Lung;  Leung, Chung-Hang
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Redox-sensitive micelles composed of disulfide-linked Pluronic-linoleic acid for enhanced anticancer efficiency of brusatol Journal article
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2018,Volume: 13,Page: 939-956
Authors:  Zhane, Jinming;  Fang, Xiaobin;  Li, Zeyong;  Chan, Hon Fai;  Lin, Zhixiu;  Wang, Yitao;  Chen, Meiwan
View  |  Adobe PDF(704Kb)  |  Favorite  |  View/Download:500/17  |  Submit date:2018/10/30
Poloxamer188  Tumor Micro-environment  Glutathione  Brucea Javanica  Cancer Treatment  
Identification of a rhodium(III) complex as a Wee1 inhibitor against: TP53 -mutated triple-negative breast cancer cells Journal article
Chemical Communications, 2018,Volume: 54,Issue: 20,Page: 2463-2466
Authors:  Yang G.-J.;  Zhong H.-J.;  Ko C.-N.;  Wong S.-Y.;  Vellaisamy K.;  Ye M.;  Ma D.-L.;  Leung C.-H.
Favorite  |  View/Download:10/0  |  Submit date:2018/11/06
Co-delivery of gambogic acid and TRAIL plasmid by hyaluronic acid grafted PEI-PLGA nanoparticles for the treatment of triple negative breast cancer Journal article
DRUG DELIVERY, 2017,Volume: 24,Issue: 1,Page: 1791-1800
Authors:  Wang, Shengpeng;  Shao, Min;  Zhong, Zhangfeng;  Wang, Anqi;  Cao, Jiliang;  Lu, Yucong;  Wang, Yitao;  Zhang, Jinming
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Nanoparticles  Trail  Gambogic Acid  Triple Negative Breast Cancer  Co-delivery  
Potential therapeutic targets of triple-negative breast cancer based on its intrinsic subtype Journal article
ONCOTARGET, 2017,Volume: 8,Issue: 42,Page: 73329-73344
Authors:  Shao, Fangyuan;  Sun, Heng;  Deng, Chu-Xia
Favorite  |  View/Download:14/0  |  Submit date:2018/10/30
Cancer Therapy  Tnbc Subtype  Cscs  Drug Resistance  Cancer Targets  
FOXC1 is associated with estrogen receptor and affects sensitivity of tamoxifen treatment in breast cancer Conference paper
Authors:  Wang, Jin-hua;  Xu, Ya-li;  Chen, Xiu-ping;  Li, Li;  Wang, Lin;  Yao, Ru;  Sun, Qiang;  Du, Guan-hua
Favorite  |  View/Download:5/0  |  Submit date:2018/10/30
breast cancer  estrogen receptor  FOXC1  TCGA  triple negative