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Novel neurotoxic peptides from Protopalythoa variabilis virtually interact with voltage-gated sodium channel and display anti-epilepsy and neuroprotective activities in zebrafish Journal article
Archives of Toxicology, 2019,Volume: 93,Issue: 1,Page: 189-206
Authors:  Liao Q.;  Li S.;  Siu S.W.I.;  Morlighem J.-E.R.L.;  Wong C.T.T.;  Wang X.;  Radis-Baptista G.;  Lee S.M.-Y.
Favorite  |  View/Download:18/0  |  Submit date:2019/04/04
Anti-epilepsy  Disulfide Bond  Neuroactive Peptides  Neuroprotection  Protein Docking  Voltage-gated Sodium Ion Channel Blocker  
Gallic acid, a natural polyphenol, protects against tert-butyl hydroperoxide- induced hepatotoxicity by activating ERK-Nrf2-Keap1-mediated antioxidative response Journal article
Food and Chemical Toxicology, 2018,Volume: 119,Page: 479-488
Authors:  Feng R.-B.;  Wang Y.;  He C.;  Yang Y.;  Wan J.-B.
Favorite  |  View/Download:6/0  |  Submit date:2018/12/28
Gallic Acid  Nuclear Factor Erythroid 2-related Factor 2  Oxidative Stress  Tert-butyl Hydroperoxide  
Gallic acid, a natural polyphenol, protects against tert-butyl hydroperoxide-induced hepatotoxicity by activating ERK-Nrf2-Keap1-mediated antioxidative response Journal article
Food and Chemical Toxicology, 2018,Volume: 119,Page: 479-488
Authors:  Feng, RB;  Wang, Y;  He, CW;  Yang, Y;  Wan, JB
Favorite  |  View/Download:14/0  |  Submit date:2020/01/09
gamma-Mangostin, a xanthone from mangosteen, attenuates oxidative injury in liver via NRF2 and SIRT1 induction Journal article
JOURNAL OF FUNCTIONAL FOODS, 2018,Volume: 40,Page: 544-553
Authors:  Wang, Anqi;  Li, Dan;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Lin, Ligen
View  |  Adobe PDF(1410Kb)  |  Favorite  |  View/Download:515/19  |  Submit date:2018/10/30
Gamma-mangostin  Mangosteen  Liver Oxidative Injury  Nrf2  Sirt1  Pgc-1 Alpha  
Geniposide improves insulin production and reduces apoptosis in high glucose-induced glucotoxic insulinoma cells Journal article
European Journal of Pharmaceutical Sciences, 2017,Volume: 110,Page: 70-76
Authors:  Guo L.X.;  Liu J.H.;  Zheng X.X.;  Yin Z.Y.;  Kosaraju J.;  Tam K.Y.
Favorite  |  View/Download:15/0  |  Submit date:2018/12/18
Apoptosis  Geniposide  Glucose-stimulated Insulin Secretion  Glucotoxicity  
Sichuan pepper attenuates H2O2-induced apoptosis via antioxidant activity and up-regulating heme oxygenase-1 gene expression in primary rat hepatocytes Journal article
JOURNAL OF FOOD BIOCHEMISTRY, 2017,Volume: 41,Issue: 6
Authors:  Zhang, Huan;  Zhou, Xuelin;  Wong, Marcus Ho-Yin;  Man, Ka-Yi;  Pin, Wing-Kwan;  Yeung, John Hok-Keung;  Kwan, Yiu-Wa;  Leung, George Pak-Heng;  Hoi, Pui-Man;  Lee, Simon Ming-Yuen;  Chan, Chi-On;  Mok, Daniel Kam-Wah;  Yu, Peter Hoi-Fu;  Chan, Shun-Wan
Favorite  |  View/Download:23/0  |  Submit date:2018/10/30
Liver  Reactive Oxygen Species  Rutaceae  Zanthoxylum Bungeanum Maxim  
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
View  |  Adobe PDF(2766Kb)  |  Favorite  |  View/Download:507/10  |  Submit date:2018/10/31
Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
Agrimonolide and desmethylagrimonolide induced HO-1 expression in HepG2 cells through Nrf2-transduction and p38 inactivation Journal article
Frontiers in Pharmacology, 2017,Volume: 7,Issue: JAN
Authors:  Chen L.;  Teng H.;  Zhang K.Y.;  Skalicka-Wozniak K.;  Georgiev M.I.;  Xiao J.
Favorite  |  View/Download:7/0  |  Submit date:2019/01/15
Agrimonolide  Desmethylagrimonolide  Heme oxygenase-1  HepG2 cells  Nrf2  P38 MAPK signaling pathway  
Agrimonolide and Desmethylagrimonolide Induced HO-1 Expression in HepG2 Cells through Nrf2-Transduction and p38 Inactivation Journal article
FRONTIERS IN PHARMACOLOGY, 2017,Volume: 7
Authors:  Chen, Lei;  Teng, Hui;  Zhang, Kalin Yanbo;  Skalicka-Wozniak, Krystyna;  Georgiev, Milen I.;  Xiao, Jianbo
Favorite  |  View/Download:21/0  |  Submit date:2018/10/30
agrimonolide  desmethylagrimonolide  HepG2 cells  Nrf2  heme oxygenase-1  p38 MAPK signaling pathway  
Bio-assay guided identification of hepatoprotective polyphenols from Penthorum chinense Pursh on t-BHP induced oxidative stress injured L02 cells Journal article
FOOD & FUNCTION, 2016,Volume: 7,Issue: 4,Page: 2074-2083
Authors:  Anqi Wang;  Shengpeng Wang;  Yun Jiang;  Meiwan Chen;  Yitao Wang;  Ligen Lin
Favorite  |  View/Download:8/0  |  Submit date:2020/04/01