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Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 10,Page: 1279-1291
Authors:  Lei Fan;  Xiao-xia Qiu;  Zhi-yuan Zhu;  Jian-lu Lv;  Jian Lu;  Fei Mao;  Jin Zhu;  Jia-ying Wang;  Xiao-wei Guan;  Jing Chen;  Jin Ren;  Ji-ming Ye;  Yong-hua Zhao;  Jian Li;  Xu Shen
Favorite  |  View/Download:15/0  |  Submit date:2020/04/14
App/ps1 Transgenic Mice  Alzheimer’s Disease  Autophagy  Inflammation  Nitazoxanide  
The effects of bioactive components from the rhizome of Salvia miltiorrhiza (Danshen) on the characteristics of Alzheimer's disease Journal article
Chinese Medicine, 2019,Volume: 14
Authors:  Cheong‑Meng Chong;  Huanxing Su;  Jin‑Jian Lu;  Yitao Wang
Favorite  |  View/Download:8/0  |  Submit date:2020/03/27
Alzheimer’s Disease  Danshen  Amyloid β Plaques  Neurofbrillary Tangles  Mitochondrial Dysfunction  Autophagy  
The effects of bioactive components from the rhizome of Salvia miltiorrhiza(Danshen) on the characteristics of Alzheimer’s disease Journal article
CHINESE MEDICINE, 2019
Authors:  Cheong‑Meng Chong;  Huanxing Su;  Jin‑Jian Lu;  Yitao Wang
Favorite  |  View/Download:8/0  |  Submit date:2020/04/08
Alzheimer’s Disease  Amyloid β Plaques  Neurofibrillary Tangles  Mitochondrial Dysfunction  Autophagy  Danshen  
Anti-neuroinflammatory effects of SLOH in A beta-induced BV-2 microglial cells and 3xTg-AD mice involve the inhibition of GSK-3 beta Journal article
NEUROSCIENCE LETTERS, 2018,Volume: 687,Page: 207-215
Authors:  Wu, Xiaoli;  Kosaraju, Jayasankar;  Tam, Kin Yip
Favorite  |  View/Download:12/0  |  Submit date:2019/01/17
SLOH  BV-2 cells  3xTg-AD mice  Neuroinflammation  GSK-3 beta  
The effect of V-ATPase function defects in pathogenesis of Alzheimer's disease Journal article
CNS NEUROSCIENCE & THERAPEUTICS, 2018,Volume: 24,Issue: 9,Page: 837-840
Authors:  Zhao, Zi-Wei;  Yuan, Zhen;  Zhao, De-Qiang;  Wang, Zhan-Wen;  Zhu, Fei-Qi;  Luan, Ping
Favorite  |  View/Download:13/0  |  Submit date:2018/10/31
A rare variant in MLKL confers susceptibility to ApoE ɛ4-negative Alzheimer's disease in Hong Kong Chinese population Journal article
Neurobiology of Aging, 2018,Volume: 68,Page: 160.e1-160.e7
Authors:  Wang B.;  Bao S.;  Zhang Z.;  Zhou X.;  Wang J.;  Fan Y.;  Zhang Y.;  Li Y.;  Chen L.;  Jia Y.;  Li J.;  Li M.;  Zheng W.;  Mu N.;  Wang L.;  Yu Z.;  Wong D.S.M.;  Zhang Y.;  Kwan J.;  Ka-Fung Mak H.;  Ambalavanan A.;  Zhou S.;  Cai W.;  Zheng J.;  Huang S.;  Rouleau G.A.;  Yang W.;  Rogaeva E.;  Ma X.;  St George-Hyslop P.;  Chu L.W.;  Song Y.-Q.
Favorite  |  View/Download:13/0  |  Submit date:2018/12/21
Apoe Ɛ4-negative  Late-onset Alzheimer's Disease  Mlkl  Whole Exome Sequencing  
Effects of insulin on transcriptional response and permeability in an in vitro model of human blood-brain barrier Journal article
JOURNAL OF CELLULAR BIOCHEMISTRY, 2018,Volume: 119,Issue: 7,Page: 5657-5664
Authors:  Kuai, Ziyu;  Xu, Yan;  Zhao, Qi;  Liu, Jie;  Guan, Shanshan;  Qiao, Yongbo;  Gong, Xin;  Nie, Jiaojiao;  Li, Pengju;  Liu, Dongni;  Xing, Yifan;  Li, Huiwen;  Sun, Zixiao;  Wang, Wenqi;  Ning, Chunan;  Shi, Yuhua;  Kong, Wei;  Shan, Yaming
Favorite  |  View/Download:36/0  |  Submit date:2018/10/30
Alzheimer's Disease  Human Blood-brain Barrier  Insulin  Type 2 Diabetes  Transcriptional Response  Permeability  
A reciprocal relationship between reactive oxygen species and mitochondrial dynamics in neurodegeneration Journal article
REDOX BIOLOGY, 2018,Volume: 14,Page: 7-19
Authors:  Hung, Clara Hiu-Ling;  Cheng, Sally Shuk-Yee;  Cheung, Yuen-Ting;  Wuwongse, Suthicha;  Zhang, Natalie Qishan;  Ho, Yuen-Shan;  Lee, Simon Ming-Yuen;  Chang, Raymond Chuen-Chung
Favorite  |  View/Download:26/0  |  Submit date:2018/10/30
Alzheimer's Disease  Beta-amyloid  Mitochondria  Fission And Fusion  Drp-1  Neurodegeneration  
SLOH, a carbazole-based fluorophore, mitigates neuropathology and behavioral impairment in the triple-transgenic mouse model of Alzheimer's disease Journal article
NEUROPHARMACOLOGY, 2018,Volume: 131,Page: 351-363
Authors:  Wu, Xiaoli;  Kosaraju, Jayasankar;  Zhou, Wei;  Tam, Kin Yip
Favorite  |  View/Download:14/0  |  Submit date:2018/10/31
Amyloid beta  Aggregation  Alzheimer's disease  3xTg-AD  Neuroprotection  SH-SY5Y  
A Novel Tetramethylpyrazine Derivative Prophylactically Protects against Glutamate-Induced Excitotoxicity in Primary Neurons through the Blockage of N-Methyl-D-aspartate Receptor Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Hu, Shengquan;  Hu, Huihui;  Mak, Shinghung;  Cui, Guozhen;  Lee, Mingyuen;  Shan, Luchen;  Wang, Yuqiang;  Lin, Huangquan;  Zhang, Zaijun;  Han, Yifan
Favorite  |  View/Download:23/0  |  Submit date:2018/10/30
Alzheimer's disease  tetramethylpyrazine derivative  NMDA receptor  neuroprotection  oxidative stress  GSK3 beta