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Anti-neuroinflammatory effects of SLOH in Aβ-induced BV-2 microglial cells and 3xTg-AD mice involve the inhibition of GSK-3β Journal article
Neuroscience Letters, 2018,Volume: 687,Page: 207-215
Authors:  Wu X.;  Kosaraju J.;  Tam K.Y.
Favorite | View/Download:2/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2018/12/18
3xTg-AD mice  BV-2 cells  GSK-3β  Neuroinflammation  SLOH  
A rare variant in MLKL confers susceptibility to ApoE ɛ4-negative Alzheimer's disease in Hong Kong Chinese population Journal article
Neurobiology of Aging, 2018,Volume: 68,Page: 160.e1-160.e7
Authors:  Wang B.;  Bao S.;  Zhang Z.;  Zhou X.;  Wang J.;  Fan Y.;  Zhang Y.;  Li Y.;  Chen L.;  Jia Y.;  Li J.;  Li M.;  Zheng W.;  Mu N.;  Wang L.;  Yu Z.;  Wong D.S.M.;  Zhang Y.;  Kwan J.;  Ka-Fung Mak H.;  Ambalavanan A.;  Zhou S.;  Cai W.;  Zheng J.;  Huang S.;  Rouleau G.A.;  Yang W.;  Rogaeva E.;  Ma X.;  St George-Hyslop P.;  Chu L.W.;  Song Y.-Q.
Favorite | View/Download:16/0 | TC[WOS]:5 TC[Scopus]:0 | Submit date:2018/12/21
Apoe Ɛ4-negative  Late-onset Alzheimer's Disease  Mlkl  Whole Exome Sequencing  
Effects of insulin on transcriptional response and permeability in an in vitro model of human blood-brain barrier Journal article
JOURNAL OF CELLULAR BIOCHEMISTRY, 2018,Volume: 119,Issue: 7,Page: 5657-5664
Authors:  Kuai, Ziyu;  Xu, Yan;  Zhao, Qi;  Liu, Jie;  Guan, Shanshan;  Qiao, Yongbo;  Gong, Xin;  Nie, Jiaojiao;  Li, Pengju;  Liu, Dongni;  Xing, Yifan;  Li, Huiwen;  Sun, Zixiao;  Wang, Wenqi;  Ning, Chunan;  Shi, Yuhua;  Kong, Wei;  Shan, Yaming
Favorite | View/Download:38/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2018/10/30
Alzheimer's Disease  Human Blood-brain Barrier  Insulin  Type 2 Diabetes  Transcriptional Response  Permeability  
Circadian rhythm dysfunction accelerates disease progression in a mouse model with amyotrophic lateral sclerosis Journal article
Frontiers in Neurology, 2018,Volume: 9,Issue: APR
Authors:  Huang Z.;  Liu Q.;  Peng Y.;  Dai J.;  Xie Y.;  Chen W.;  Long S.;  Pei Z.;  Su H.;  Yao X.
Favorite | View/Download:12/0 | TC[WOS]:7 TC[Scopus]:0 | Submit date:2018/12/28
Amyotrophic lateral sclerosis  Circadian rhythm dysfunction  Cyanobacteria  Inflammation  NF-κB  
A Novel Tetramethylpyrazine Derivative Prophylactically Protects against Glutamate-Induced Excitotoxicity in Primary Neurons through the Blockage of N-Methyl-D-aspartate Receptor Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Hu, Shengquan;  Hu, Huihui;  Mak, Shinghung;  Cui, Guozhen;  Lee, Mingyuen;  Shan, Luchen;  Wang, Yuqiang;  Lin, Huangquan;  Zhang, Zaijun;  Han, Yifan
Favorite | View/Download:23/0 | TC[WOS]:6 TC[Scopus]:0 | Submit date:2018/10/30
Alzheimer's disease  tetramethylpyrazine derivative  NMDA receptor  neuroprotection  oxidative stress  GSK3 beta  
Injected Amyloid Beta in the Olfactory Bulb Transfers to Other Brain Regions via Neural Connections in Mice Journal article
MOLECULAR NEUROBIOLOGY, 2018,Volume: 55,Issue: 2,Page: 1703-1713
Authors:  He, Baixuan;  Zheng, Minying;  Liu, Qiang;  Shi, Zhe;  Long, Simei;  Lu, Xilin;  Pei, Zhong;  Yuan, Ti-Fei;  Su, Huanxing;  Yao, Xiaoli
Favorite | View/Download:20/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2018/10/30
Alzheimer's Disease  Oligomers  Olfactory Pathway  Neural Connections  Apoptosis  
Research and development of anti-Alzheimer's disease drugs: an update from the perspective of technology flows Journal article
EXPERT OPINION ON THERAPEUTIC PATENTS, 2018,Volume: 28,Issue: 4,Page: 341-350
Authors:  Liu, Kunmeng;  Lin, Hui-Heng;  Pi, Rongbiao;  Mak, Shinghung;  Han, Yifan;  Hu, Yuanjia
Favorite | View/Download:18/0 | TC[WOS]:4 TC[Scopus]:0 | Submit date:2018/10/30
Alzheimer's disease  patent  technology flow  citation network  research and development  
SLM, a novel carbazole-based fluorophore attenuates okadaic acid-induced tau hyperphosphorylation via down-regulating GSK-3β activity in SH-SY5Y cells Journal article
European Journal of Pharmaceutical Sciences, 2017,Volume: 110,Page: 101-108
Authors:  Wu X.;  Kosaraju J.;  Tam K.Y.
Favorite | View/Download:22/0 | TC[WOS]:8 TC[Scopus]:0 | Submit date:2018/12/18
Alzheimer's Disease  Glycogen Synthase Kinase-3β  Okadaic Acid  Slm  Tau Hyperphosphorylation  
Artemisinin protects PC12 cells against β-amyloid-induced apoptosis through activation of the ERK1/2 signaling pathway Journal article
Redox Biology, 2017,Volume: 12,Page: 625-633
Authors:  Zeng Z.;  Xu J.;  Zheng W.
Favorite | View/Download:7/0 | TC[WOS]:28 TC[Scopus]:0 | Submit date:2018/12/21
Alzheimer's Disease  Artemisinin  Aβ25–35  Erk1/2  Pc12 Cells  
Neuroprotective Effect of SLM, a Novel Carbazole-Based Fluorophore, on SH-SY5Y Cell Model and 3xTg-AD Mouse Model of Alzheimer’s Disease Journal article
ACS Chemical Neuroscience, 2017,Volume: 8,Issue: 3,Page: 676-685
Authors:  Wu X.;  Kosaraju J.;  Zhou W.;  Tam K.Y.
Favorite | View/Download:11/0 | TC[WOS]:8 TC[Scopus]:0 | Submit date:2018/12/18
3xtg-ad  Aggregation  Alzheimer’s Disease  Amyloid β  Neuroprotection  Sh-sy5y  Slm