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Anti-neuroinflammatory effects of SLOH in A beta-induced BV-2 microglial cells and 3xTg-AD mice involve the inhibition of GSK-3 beta Journal article
NEUROSCIENCE LETTERS, 2018,Volume: 687,Page: 207-215
Authors:  Wu, Xiaoli;  Kosaraju, Jayasankar;  Tam, Kin Yip
Favorite | View/Download:12/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2019/01/17
SLOH  BV-2 cells  3xTg-AD mice  Neuroinflammation  GSK-3 beta  
SLOH, a carbazole-based fluorophore, mitigates neuropathology and behavioral impairment in the triple-transgenic mouse model of Alzheimer's disease Journal article
NEUROPHARMACOLOGY, 2018,Volume: 131,Page: 351-363
Authors:  Wu, Xiaoli;  Kosaraju, Jayasankar;  Zhou, Wei;  Tam, Kin Yip
Favorite | View/Download:14/0 | TC[WOS]:4 TC[Scopus]:0 | Submit date:2018/10/31
Amyloid beta  Aggregation  Alzheimer's disease  3xTg-AD  Neuroprotection  SH-SY5Y  
SLM, a novel carbazole-based fluorophore attenuates okadaic acid-induced tau hyperphosphorylation via down-regulating GSK-3β activity in SH-SY5Y cells Journal article
European Journal of Pharmaceutical Sciences, 2017,Volume: 110,Page: 101-108
Authors:  Wu X.;  Kosaraju J.;  Tam K.Y.
Favorite | View/Download:22/0 | TC[WOS]:8 TC[Scopus]:0 | Submit date:2018/12/18
Alzheimer's Disease  Glycogen Synthase Kinase-3β  Okadaic Acid  Slm  Tau Hyperphosphorylation  
Systemic clearance and brain distribution of carbazole-based cyanine compounds as Alzheimer's disease drug candidates Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Zhou, Wei;  Hu, Xiaohui;  Tam, Kin Yip
Favorite | View/Download:17/0 | TC[WOS]:6 TC[Scopus]:0 | Submit date:2018/10/31
Linagliptin, a Dipeptidyl Peptidase-4 Inhibitor, Mitigates Cognitive Deficits and Pathology in the 3xTg-AD Mouse Model of Alzheimer's Disease Journal article
MOLECULAR NEUROBIOLOGY, 2017,Volume: 54,Issue: 8,Page: 6074-6084
Authors:  Kosaraju, Jayasankar;  Holsinger, R. M. Damian;  Guo, Lixia;  Tam, Kin Yip
Favorite | View/Download:5/0 | TC[WOS]:21 TC[Scopus]:0 | Submit date:2018/10/31
Glucagon-like peptide-1  Glucose-dependent insulinotropic polypeptide  Amyloid beta  Tau phosphorylation  Neuroinflammation  
Neuroprotective Effect of SLM, a Novel Carbazole-Based Fluorophore, on SH-SY5Y Cell Model and 3xTg-AD Mouse Model of Alzheimer’s Disease Journal article
ACS Chemical Neuroscience, 2017,Volume: 8,Issue: 3,Page: 676-685
Authors:  Wu X.;  Kosaraju J.;  Zhou W.;  Tam K.Y.
Favorite | View/Download:11/0 | TC[WOS]:8 TC[Scopus]:0 | Submit date:2018/12/18
3xtg-ad  Aggregation  Alzheimer’s Disease  Amyloid β  Neuroprotection  Sh-sy5y  Slm  
Specific frequency bands of amplitude low-frequency fluctuations in memory-related cognitive impairment: predicting Alzheimer’s disease Journal article
ADMET & DMPK, 2015,Volume: 3,Issue: 3,Page: 274-280
Authors:  Yin Tian;  Zechao Ding;  KinYip Tam;  Zhongyan Wang;  Huiling Zhang;  Dechun Zhao;  Yi Zhao;  Wei Xu;  Shuxing Zheng
Favorite | View/Download:7/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2019/01/07
Ad  Alff  Vlpfc  Rs-fmri  Top-down Modulation  
Chemical and Physical Approaches for the Treatment of Alzheimer's Disease Journal article
ADMET & DMPK, 2015,Volume: 3,Issue: 3,Page: 216-234
Authors:  Jing Li;  WeiZhou;  Xiaoli Wu;  KinTam
Favorite | View/Download:4/0 | TC[WOS]:1 TC[Scopus]:0 | Submit date:2019/01/07
Alzheimer’s Disease  Β-amyloid Peptide  Tau Protein  Pharmacological Strategies  Deep Brain Stimulation  Neurobiological Pathogenesis