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Activatable Small-Molecule Photoacoustic Probes that Cross the Blood-Brain Barrier for Visualization of Copper(II) in Mice with Alzheimer's Disease Journal article
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019,Volume: 58,Issue: 36,Page: 12415-12419
Authors:  Shichao Wang;  Zonghai Sheng;  Zhenguo Yang;  Dehong Hu;  Xiaojing Long;  Gang Feng;  Yubin Liu;  Zhen Yuan;  Jingjing Zhang;  Hairong Zheng;  Xuanjun Zhang
Favorite | View/Download:19/0 | TC[WOS]:8 TC[Scopus]:0 | Submit date:2020/05/26
Alzheimer's Disease  Biosensors  Blood-brain Barrier  Copper  Photoacoustic Probe  
Abnormal dynamic functional connectivity and brain states in Alzheimer's diseases: functional near-infrared spectroscopy study Journal article
NEUROPHOTONICS, 2019,Volume: 6,Issue: 2
Authors:  Haijing Niu;  Zhaojun Zhu;  Mengjing Wang;  Xuanyu Li;  Zhen Yuan;  Yu Sun;  Ying Han
Favorite | View/Download:8/0 | TC[WOS]:4 TC[Scopus]:0 | Submit date:2020/06/24
Resting State  Functional Connectivity  Sliding-window  K-means Clustering  Brain Network  Alzheimer's Disease  
Anti-neuroinflammatory effects of SLOH in A beta-induced BV-2 microglial cells and 3xTg-AD mice involve the inhibition of GSK-3 beta Journal article
NEUROSCIENCE LETTERS, 2018,Volume: 687,Page: 207-215
Authors:  Wu, Xiaoli;  Kosaraju, Jayasankar;  Tam, Kin Yip
Favorite | View/Download:12/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2019/01/17
SLOH  BV-2 cells  3xTg-AD mice  Neuroinflammation  GSK-3 beta  
The effect of V-ATPase function defects in pathogenesis of Alzheimer's disease Journal article
CNS NEUROSCIENCE & THERAPEUTICS, 2018,Volume: 24,Issue: 9,Page: 837-840
Authors:  Zhao, Zi-Wei;  Yuan, Zhen;  Zhao, De-Qiang;  Wang, Zhan-Wen;  Zhu, Fei-Qi;  Luan, Ping
Favorite | View/Download:13/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2018/10/31
A rare variant in MLKL confers susceptibility to ApoE ɛ4-negative Alzheimer's disease in Hong Kong Chinese population Journal article
Neurobiology of Aging, 2018,Volume: 68,Page: 160.e1-160.e7
Authors:  Wang B.;  Bao S.;  Zhang Z.;  Zhou X.;  Wang J.;  Fan Y.;  Zhang Y.;  Li Y.;  Chen L.;  Jia Y.;  Li J.;  Li M.;  Zheng W.;  Mu N.;  Wang L.;  Yu Z.;  Wong D.S.M.;  Zhang Y.;  Kwan J.;  Ka-Fung Mak H.;  Ambalavanan A.;  Zhou S.;  Cai W.;  Zheng J.;  Huang S.;  Rouleau G.A.;  Yang W.;  Rogaeva E.;  Ma X.;  St George-Hyslop P.;  Chu L.W.;  Song Y.-Q.
Favorite | View/Download:16/0 | TC[WOS]:5 TC[Scopus]:0 | Submit date:2018/12/21
Apoe Ɛ4-negative  Late-onset Alzheimer's Disease  Mlkl  Whole Exome Sequencing  
Effects of insulin on transcriptional response and permeability in an in vitro model of human blood-brain barrier Journal article
JOURNAL OF CELLULAR BIOCHEMISTRY, 2018,Volume: 119,Issue: 7,Page: 5657-5664
Authors:  Kuai, Ziyu;  Xu, Yan;  Zhao, Qi;  Liu, Jie;  Guan, Shanshan;  Qiao, Yongbo;  Gong, Xin;  Nie, Jiaojiao;  Li, Pengju;  Liu, Dongni;  Xing, Yifan;  Li, Huiwen;  Sun, Zixiao;  Wang, Wenqi;  Ning, Chunan;  Shi, Yuhua;  Kong, Wei;  Shan, Yaming
Favorite | View/Download:38/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2018/10/30
Alzheimer's Disease  Human Blood-brain Barrier  Insulin  Type 2 Diabetes  Transcriptional Response  Permeability  
SLOH, a carbazole-based fluorophore, mitigates neuropathology and behavioral impairment in the triple-transgenic mouse model of Alzheimer's disease Journal article
NEUROPHARMACOLOGY, 2018,Volume: 131,Page: 351-363
Authors:  Wu, Xiaoli;  Kosaraju, Jayasankar;  Zhou, Wei;  Tam, Kin Yip
Favorite | View/Download:14/0 | TC[WOS]:4 TC[Scopus]:0 | Submit date:2018/10/31
Amyloid beta  Aggregation  Alzheimer's disease  3xTg-AD  Neuroprotection  SH-SY5Y  
Human amyloid β peptide and tau co-expression impairs behavior and causes specific gene expression changes in Caenorhabditis elegans Journal article
Neurobiology of Disease, 2018,Volume: 109,Page: 88-101
Authors:  Wang C.;  Saar V.;  Leung K.L.;  Chen L.;  Wong G.
Favorite | View/Download:7/0 | TC[WOS]:9 TC[Scopus]:0 | Submit date:2018/12/18
Alzheimer's Disease  Amyloid Beta  Caenorhabditis Elegans  Rna Interference  Tau  Transcriptome Analysis  
The association between urinary Alzheimer-associated neuronal thread protein and cognitive impairment in late-life depression: a controlled pilot study Journal article
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2018,Volume: 14,Issue: 11,Page: 1497-1502
Authors:  Zhang, Qing-E;  Ling, Sihai;  Li, Peng;  Zhang, Saina;  Ng, Chee H.;  Ungvari, Gabor S.;  Wang, Liang-Jen;  Lee, Sheng-Yu;  Wang, Gang;  Xiang, Yu-Tao
Favorite | View/Download:26/0 | TC[WOS]:4 TC[Scopus]:0 | Submit date:2018/10/30
Ad7c-ntp  Alzheimer's Disease  Late-life Depression  Cognitive Impairment  
SLM, a novel carbazole-based fluorophore attenuates okadaic acid-induced tau hyperphosphorylation via down-regulating GSK-3β activity in SH-SY5Y cells Journal article
European Journal of Pharmaceutical Sciences, 2017,Volume: 110,Page: 101-108
Authors:  Wu X.;  Kosaraju J.;  Tam K.Y.
Favorite | View/Download:22/0 | TC[WOS]:8 TC[Scopus]:0 | Submit date:2018/12/18
Alzheimer's Disease  Glycogen Synthase Kinase-3β  Okadaic Acid  Slm  Tau Hyperphosphorylation