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| Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells Journal article
Acta Pharmaceutica Sinica B, 2020,Volume: 10,Issue: 4,Page: 615-627
Authors: Zhang，Baoyuan; Lyu，Junfang; Yang，Eun Ju; Liu，Yifan; Wu，Changjie; Pardeshi，Lakhansing; Tan，Kaeling; Chen，Qiang; Xu，Xiaoling; Deng，Chu Xia; Shim，Joong Sup
  Favorite | View/Download：76/0 | TC[WOS]:0 TC[Scopus]:4 | Submit date：2020/09/16
BRCA1 Breast cancer DNA damage HDAC Histone deacetylase Reactive oxygen species Synthetic lethality |
| The metabolic footprint during adipocyte commitment highlights ceramide modulation as an adequate approach for obesity treatment Journal article
EBioMedicine, 2020,Volume: 51
Authors: Hou，Weilong; Chen，Qiang; Wang，Haitao; Qiu，Pengxiang; Lyu，Xueying; Chen，Weiping; Chua，Melvin L.K.; Chinn，Y. Eugene; Deng，Chu Xia; Wang，Ruihong
Favorite | View/Download：74/0 | TC[WOS]:0 TC[Scopus]:1 | Submit date：2020/09/16
Adipogenesis Apoptosis Ceramide Epigenetic modification Metabolic landscape Metabolomics Obesity |
| Rmrp Mutation Disrupts Chondrogenesis and Bone Ossification in Zebrafish Model of Cartilage-Hair Hypoplasia via Enhanced Wnt/β-Catenin Signaling Journal article
Journal of Bone and Mineral Research, 2019,Volume: 34,Issue: 11,Page: 2101-2116
Authors: Sun，Xianding; Zhang，Ruobin; Liu，Mi; Chen，Hangang; Chen，Liang; Luo，Fengtao; Zhang，Dali; Huang，Junlan; Li，Fangfang; Ni，Zhenhong; Qi，Huabing; Su，Nan; Jin，Min; Yang，Jing; Tan，Qiaoyan; Du，Xiaolan; Chen，Bo; Huang，Haiyang; Chen，Shuai; Yin，Liangjun; Xu，Xiaoling; Deng，Chuxia ; Luo，Lingfei; Xie，Yangli; Chen，Lin
Favorite | View/Download：76/0 | TC[WOS]:2 TC[Scopus]:4 | Submit date：2020/09/16
CARTILAGE-HAIR HYPOPLASIA RMRP SKELETAL DEVELOPMENT WNT/Β-CATENIN ZEBRAFISH |
| A novel dual sensitive polymer-gambogic acid conjugate: synthesis, characterization, and in vitro evaluation Journal article
NANOTECHNOLOGY, 2019,Volume: 30,Issue: 50
Authors: Ke Song; Zhaobo Wang; Xue Liu; Guolin Zhang; Xin Wang; DeFang Ouyang; Mingrui Guo; Lijiang Chen
Favorite | View/Download：19/0 | TC[WOS]:3 TC[Scopus]:1 | Submit date：2020/03/25
Polymer-drug Conjugate Gambogic Acid Sensitive Drug Delivery Cathepsin b Glutathione |
| Metformin protects PC12 cells and hippocampal neurons from H2O (2)-induced oxidative damage through activation of AMPK pathway Journal article
JOURNAL OF CELLULAR PHYSIOLOGY, 2019,Volume: 234,Issue: 9,Page: 16619-16629
Authors: Xia Zhao; Zhiwen Zeng; Uma Gaur; Jiankang Fang; Tangming Peng; Shuai Li; Wenhua Zheng
Favorite | View/Download：14/0 | TC[WOS]:8 TC[Scopus]:12 | Submit date：2020/06/11
Aging Amp-activated Protein Kinase Hydrogen Peroxide Metformin Pc12 Cells |
| Nuclear localization of Desmoplakin and its involvement in telomere maintenance Journal article
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2019,Volume: 15,Issue: 11,Page: 2350-2362
Authors: Peipei Li; Yuan Meng; Yuan Wang; Jingjing Li; Manting Lam; Li Wang; Li-jun Di
Favorite | View/Download：19/0 | TC[WOS]:1 TC[Scopus]:2 | Submit date：2020/05/21
Crispr Bioid Telomere Dsp |
| Insulin Stimulates PI3K/AKT and Cell Adhesion to Promote the Survival of Individualized Human Embryonic Stem Cells Journal article
STEM CELLS, 2019,Volume: 37,Issue: 8,Page: 1030-1041
Authors: Carlos Godoy‐Parejo; Chunhao Deng; Weiwei Liu; Guokai Chen
Favorite | View/Download：19/0 | TC[WOS]:3 TC[Scopus]:6 | Submit date：2020/05/21
Hesc Cell Survival Cell Adhesion Focal Adhesion Niche Individualization Insulin Integrin Caspase Igf Akt |
| Discovery of fused bicyclic derivatives of 1H-pyrrolo[1,2-c]imidazol-1-one as VDR signaling regulators Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2019,Volume: 27,Issue: 17,Page: 3879-3888
Authors: Bin Xu; Mo-Yu Ding; Zhibing Weng; Zheng-Qing Li; Feng Li; Xia Sun; Qiu-Ling Chen; Yi-Tao Wang; Ying Wang; Guo-Chun Zhou
Favorite | View/Download：12/0 | TC[WOS]:0 TC[Scopus]:3 | Submit date：2020/05/05
1h-pyrrolo[1,2-c]Imidazol-1-one Vitamin d Receptor (Vdr) Autophagy Apoptosis |
| An Eco- and User-Friendly Herbicide Journal article
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019,Volume: 67,Issue: 28,Page: 7783-7792
Authors: Xiangjun Zhang; Qiaoxian Huang; Zhe-Ze Zhao; Xiaoqiu Xu; Shengke Li; Hang Yin; Lanlan Li; Jianxiang Zhang; Ruibing Wang
Favorite | View/Download：21/0 | TC[WOS]:3 TC[Scopus]:5 | Submit date：2020/04/02
Friendly Herbicide Paraquat Cucurbit[7]Uril Upramolecular Chemistry |
| A Danshensu-Tetramethylpyrazine Conjugate DT-010 Overcomes Multidrug Resistance in Human Breast Cancer Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors: Xinhua Zhou; Anqi Wang; Liang Wang; Jianhua Yin; Li Wang; Lijun Di; Maggie Pui-Man Hoi; Luchen Shan; Xu Wu; Yuqiang Wang
Favorite | View/Download：14/0 | TC[WOS]:2 TC[Scopus]:3 | Submit date：2020/05/21
Danshensu Tetramethylpyrazine Breast Cancer Resistance Glycolysis P-glycoprotein |
