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Neuroprotective Effects of BHDPC, a Novel Neuroprotectant, on Experimental Stroke by Modulating Microglia Polarization Journal article
ACS CHEMICAL NEUROSCIENCE, 2019,Volume: 10,Issue: 5,Page: 2434-2449
Authors:  Chuwen Li;  Yaqi Bian;  Yu Feng;  Fan Tang;  Liang Wang;  Maggie Pui Man Hoi;  Dan Ma;  Chao Zhao;  Simon Ming Yuen Lee
Favorite | View/Download:225/0 | TC[WOS]:4 TC[Scopus]:0 | Submit date:2020/01/16
Bhdpc  Ischemic Stroke  Microglia  Nf-κb  Creb  Pka  
Myricanol rescues dexamethasone‐induced muscle dysfunction via a sirtuin 1‐dependent mechanism Journal article
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2019,Volume: 10,Issue: 2,Page: 429-444
Authors:  Shengnan Shen;  Qiwen Liao;  Jingxin Liu;  Ruile Pan;  Simon Ming-Yuen Lee;  Ligen Lin1
Favorite | View/Download:6/0 | TC[WOS]:7 TC[Scopus]:0 | Submit date:2020/05/07
Autophagy  Dexamethasone  Muscle Atrophy  Myricanol  Pgc-1α  Sirt1  
Myricanol rescues dexamethasone-induced muscle dysfunction via a sirtuin 1-dependent mechanism Journal article
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2019,Volume: 10,Issue: 2,Page: 429-444
Authors:  Shen, SN;  Liao, QW;  Liu, JX;  Pan, RL;  Lee, SMY;  Lin, LG
Favorite | View/Download:227/0 | TC[WOS]:7 TC[Scopus]:0 | Submit date:2020/01/16
Autophagy  Myricanol  Sirt1  Dexamethasone  Muscle Atrophy  Pgc-1 Alpha  
Hepatoprotective Effect of Jianpi Huoxue Formula on Nonalcoholic Fatty Liver Disease Induced by Methionine-Choline-Deficient Diet in Rat Journal article
BIOMED RESEARCH INTERNATIONAL, 2019,Volume: 2019
Authors:  Yu Feng;  Yan Chen;  Binrui Yang;  Qingping Lan;  Tao Wang;  Guozhen Cui;  Zhitao Ren;  I. Cheong Choi;  George Pak-Heng Leung;  Fenggen Yan;  Dacan Chen;  Hon Ho Yu;  Simon Ming Yuen Lee
Favorite | View/Download:238/0 | TC[WOS]:1 TC[Scopus]:0 | Submit date:2020/01/16
Pinostrobin Exerts Neuroprotective Actions in Neurotoxin-Induced Parkinson's Disease Models through Nrf2 Induction Journal article
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2018,Volume: 66,Issue: 31,Page: 8307-8318
Authors:  Li, Chuwen;  Tang, Benqin;  Feng, Yu;  Tang, Fan;  Hoi, Maggie Pui-Man;  Su, Ziren;  Lee, Simon Ming-Yuen
Favorite | View/Download:17/0 | TC[WOS]:11 TC[Scopus]:0 | Submit date:2018/10/31
Pinostrobin  Parkinson's Disease  Neurotoxin  Nrf2  
A reciprocal relationship between reactive oxygen species and mitochondrial dynamics in neurodegeneration Journal article
REDOX BIOLOGY, 2018,Volume: 14,Page: 7-19
Authors:  Hung, Clara Hiu-Ling;  Cheng, Sally Shuk-Yee;  Cheung, Yuen-Ting;  Wuwongse, Suthicha;  Zhang, Natalie Qishan;  Ho, Yuen-Shan;  Lee, Simon Ming-Yuen;  Chang, Raymond Chuen-Chung
Favorite | View/Download:26/0 | TC[WOS]:40 TC[Scopus]:0 | Submit date:2018/10/30
Alzheimer's Disease  Beta-amyloid  Mitochondria  Fission And Fusion  Drp-1  Neurodegeneration  
A novel compound DT-010 protects against doxorubicin-induced cardiotoxicity in zebrafish and H9c2 cells by inhibiting reactive oxygen species-mediated apoptotic and autophagic pathways Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 820,Page: 86-96
Authors:  Tang, Fan;  Zhou, Xinhua;  Wang, Liang;  Shan, Luchen;  Li, Chuwen;  Zhou, Hefeng;  Lee, Simon Ming-Yuen;  Hoi, Maggie Pui-Man
Favorite | View/Download:21/0 | TC[WOS]:16 TC[Scopus]:0 | Submit date:2018/10/30
Cardioprotection  Anti-oxidative Stress  Anti-apoptosis  Autophagy Regulation  Zebrafish Cardiotoxicity  H9c2 Cardiomyocytes  
Sichuan pepper attenuates H2O2-induced apoptosis via antioxidant activity and up-regulating heme oxygenase-1 gene expression in primary rat hepatocytes Journal article
JOURNAL OF FOOD BIOCHEMISTRY, 2017,Volume: 41,Issue: 6
Authors:  Zhang, Huan;  Zhou, Xuelin;  Wong, Marcus Ho-Yin;  Man, Ka-Yi;  Pin, Wing-Kwan;  Yeung, John Hok-Keung;  Kwan, Yiu-Wa;  Leung, George Pak-Heng;  Hoi, Pui-Man;  Lee, Simon Ming-Yuen;  Chan, Chi-On;  Mok, Daniel Kam-Wah;  Yu, Peter Hoi-Fu;  Chan, Shun-Wan
Favorite | View/Download:23/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2018/10/30
Liver  Reactive Oxygen Species  Rutaceae  Zanthoxylum Bungeanum Maxim  
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
View | Adobe PDF | Favorite | View/Download:507/10 | TC[WOS]:7 TC[Scopus]:0 | Submit date:2018/10/31
Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
pH-sensitive polymeric nanoparticles for co-delivery of doxorubicin and curcumin to treat cancer via enhanced pro-apoptotic and anti-angiogenic activities Journal article
ACTA BIOMATERIALIA, 2017,Volume: 58,Page: 349-364
Authors:  Zhang, Jinming;  Li, Jingjing;  Shi, Zhi;  Yang, Yang;  Xie, Xi;  Lee, Simon MingYuen;  Wang, Yitao;  Leong, Kam W.;  Chen, Meiwan
Favorite | View/Download:22/0 | TC[WOS]:55 TC[Scopus]:0 | Submit date:2018/10/30
Anticancer  Ph-sensitive Nanoparticle  Apoptosis  Anti-angiogenesis  Co-delivery