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Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 10,Page: 1279-1291
Authors:  Lei Fan;  Xiao-xia Qiu;  Zhi-yuan Zhu;  Jian-lu Lv;  Jian Lu;  Fei Mao;  Jin Zhu;  Jia-ying Wang;  Xiao-wei Guan;  Jing Chen;  Jin Ren;  Ji-ming Ye;  Yong-hua Zhao;  Jian Li;  Xu Shen
Favorite | View/Download:15/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2020/04/14
App/ps1 Transgenic Mice  Alzheimer’s Disease  Autophagy  Inflammation  Nitazoxanide  
Discovery of fused bicyclic derivatives of 1H-pyrrolo[1,2-c]imidazol-1-one as VDR signaling regulators Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2019,Volume: 27,Issue: 17,Page: 3879-3888
Authors:  Bin Xu;  Mo-Yu Ding;  Zhibing Weng;  Zheng-Qing Li;  Feng Li;  Xia Sun;  Qiu-Ling Chen;  Yi-Tao Wang;  Ying Wang;  Guo-Chun Zhou
Favorite | View/Download:32/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2019/11/22
1h-pyrrolo[1,2-c]Imidazol-1-one  Vitamin d Receptor (Vdr)  Autophagy  Apoptosis  
Discovery of fused bicyclic derivatives of 1H-pyrrolo[1,2-c]imidazol-1-one as VDR signaling regulators Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2019,Volume: 27,Issue: 17,Page: 3879-3888
Authors:  Bin Xu;  Mo-Yu Ding;  Zhibing Weng;  Zheng-Qing Li;  Feng Li;  Xia Sun;  Qiu-Ling Chen;  Yi-Tao Wang;  Ying Wang;  Guo-Chun Zhou
Favorite | View/Download:9/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/05/05
1h-pyrrolo[1,2-c]Imidazol-1-one  Vitamin d Receptor (Vdr)  Autophagy  Apoptosis  
The effects of bioactive components from the rhizome of Salvia miltiorrhiza (Danshen) on the characteristics of Alzheimer's disease Journal article
Chinese Medicine, 2019,Volume: 14
Authors:  Cheong‑Meng Chong;  Huanxing Su;  Jin‑Jian Lu;  Yitao Wang
Favorite | View/Download:9/0 | TC[WOS]:4 TC[Scopus]:0 | Submit date:2020/03/27
Alzheimer’s Disease  Danshen  Amyloid β Plaques  Neurofbrillary Tangles  Mitochondrial Dysfunction  Autophagy  
Aurone derivatives as Vps34 inhibitors that modulate autophagy Journal article
ACTA PHARMACEUTICA SINICA B, 2019,Volume: 9,Issue: 3,Page: 537-544
Authors:  Guodong Li;  Joshua William Boyle;  Chung-Nga Ko;  Wu Zeng;  Vincent Kam Wai Wong;  Jian-Bo Wan;  Philip Wai Hong Chan;  Dik-Lung Ma;  Chung-Hang Leung
Favorite | View/Download:10/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2020/03/24
Autophagy  Natural Products  Vps34  Inhibitor  Structure-based Virtualscreening  Vesicle Trafficking  Heart Or Liver Damage  Aurone Derivative  
The effects of bioactive components from the rhizome of Salvia miltiorrhiza(Danshen) on the characteristics of Alzheimer’s disease Journal article
CHINESE MEDICINE, 2019
Authors:  Cheong‑Meng Chong;  Huanxing Su;  Jin‑Jian Lu;  Yitao Wang
Favorite | View/Download:8/0 | TC[WOS]:4 TC[Scopus]:0 | Submit date:2020/04/08
Alzheimer’s Disease  Amyloid β Plaques  Neurofibrillary Tangles  Mitochondrial Dysfunction  Autophagy  Danshen  
Myricanol rescues dexamethasone‐induced muscle dysfunction via a sirtuin 1‐dependent mechanism Journal article
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2019,Volume: 10,Issue: 2,Page: 429-444
Authors:  Shengnan Shen;  Qiwen Liao;  Jingxin Liu;  Ruile Pan;  Simon Ming-Yuen Lee;  Ligen Lin1
Favorite | View/Download:6/0 | TC[WOS]:7 TC[Scopus]:0 | Submit date:2020/05/07
Autophagy  Dexamethasone  Muscle Atrophy  Myricanol  Pgc-1α  Sirt1  
Comparative comprehension on the anti-rheumatic Chinese herbal medicine Siegesbeckiae Herba: Combined computational predictions and experimental investigations Journal article
Journal of Ethnopharmacology, 2019,Volume: 228,Page: 200-209
Authors:  Zhang Q.R.;  Zhong Z.F.;  Sang W.;  Xiong W.;  Tao H.X.;  Zhao G.D.;  Li Z.X.;  Ma Q.S.;  Tse A.K.W.;  Hu Y.J.;  Yu H.;  Wang Y.T.
Favorite | View/Download:28/0 | TC[WOS]:6 TC[Scopus]:0 | Submit date:2018/12/28
Computational Prediction  Difference  Rheumatoid Arthritis  Siegesbeckiae Herba  Similarity  
Myricanol rescues dexamethasone-induced muscle dysfunction via a sirtuin 1-dependent mechanism Journal article
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2019,Volume: 10,Issue: 2,Page: 429-444
Authors:  Shen, SN;  Liao, QW;  Liu, JX;  Pan, RL;  Lee, SMY;  Lin, LG
Favorite | View/Download:227/0 | TC[WOS]:7 TC[Scopus]:0 | Submit date:2020/01/16
Autophagy  Myricanol  Sirt1  Dexamethasone  Muscle Atrophy  Pgc-1 Alpha  
ATP13A2 facilitates HDAC6 recruitment to lysosome to promote autophagosome–lysosome fusion Journal article
JOURNAL OF CELL BIOLOGY, 2019,Volume: 218,Issue: 1,Page: 267-284
Authors:  Ruoxi Wang;  Jieqiong Tan;  Tingting Chen;  Hailong Han;  Runyi Tian;  Ya Tan;  Yiming Wu;  Jingyi Cu;  Fang Chen;  Jie Li;  Lu Lv;  Xinjie Guan;  Shuai Shang;  Jiahong Lu;  Zhuohua Zhang
Favorite | View/Download:9/0 | TC[WOS]:11 TC[Scopus]:0 | Submit date:2020/04/14