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Discovery of fused bicyclic derivatives of 1H-pyrrolo[1,2-c]imidazol-1-one as VDR signaling regulators Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2019,Volume: 27,Issue: 17,Page: 3879-3888
Authors:  Bin Xu;  Mo-Yu Ding;  Zhibing Weng;  Zheng-Qing Li;  Feng Li;  Xia Sun;  Qiu-Ling Chen;  Yi-Tao Wang;  Ying Wang;  Guo-Chun Zhou
Favorite  |  View/Download:29/0  |  Submit date:2019/11/22
1h-pyrrolo[1,2-c]Imidazol-1-one  Vitamin d Receptor (Vdr)  Autophagy  Apoptosis  
Comparative comprehension on the anti-rheumatic Chinese herbal medicine Siegesbeckiae Herba: Combined computational predictions and experimental investigations Journal article
Journal of Ethnopharmacology, 2019,Volume: 228,Page: 200-209
Authors:  Zhang Q.R.;  Zhong Z.F.;  Sang W.;  Xiong W.;  Tao H.X.;  Zhao G.D.;  Li Z.X.;  Ma Q.S.;  Tse A.K.W.;  Hu Y.J.;  Yu H.;  Wang Y.T.
Favorite  |  View/Download:27/0  |  Submit date:2018/12/28
Computational Prediction  Difference  Rheumatoid Arthritis  Siegesbeckiae Herba  Similarity  
Presenilin 1 deficiency suppresses autophagy in human neural stem cells through reducing γ-secretase-independent ERK/CREB signaling Journal article
CELL DEATH & DISEASE, 2018,Volume: 9,Page: 1-13
Authors:  Cheong-Meng Chong;  Minjing Ke;  Yuan Tan;  Zhijian Huang;  Ke Zhang;  Nana Ai;  Wei Ge;  Dajiang Qin;  Jia-Hong Lu;  Huanxing Su
Favorite  |  View/Download:36/0  |  Submit date:2018/10/30
HAMdb: a database of human autophagy modulators with specific pathway and disease information Journal article
JOURNAL OF CHEMINFORMATICS, 2018,Volume: 10
Authors:  Wang, Ning-Ning;  Dong, Jie;  Zhang, Lin;  Ouyang, Defang;  Cheng, Yan;  Chen, Alex F.;  Lu, Ai-Ping;  Cao, Dong-Sheng
Favorite  |  View/Download:25/0  |  Submit date:2018/10/30
Autophagy  Autophagy Modulator  Database  Disease  Pathophysiological  Pathway  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
View  |  Adobe PDF(3226Kb)  |  Favorite  |  View/Download:558/32  |  Submit date:2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
UPLC/Q-TOFMS-Based Metabolomics Approach to Reveal the Protective Role of Other Herbs in An-Gong-Niu-Huang Wan Against the Hepatorenal Toxicity of Cinnabar and Realgar Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Xia, Fangbo;  Li, Ao;  Chai, Yushuang;  Xiao, Xiao;  Wan, Jianbo;  Li, Peng;  Wang, Yitao
View  |  Adobe PDF(3535Kb)  |  Favorite  |  View/Download:539/23  |  Submit date:2018/10/30
An-gong-niu-huang Wan  Cinnabar  Realgar  Metabonomics  Detoxification  Inflammation  
Physalin B induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway Journal article
BIOMEDICINE & PHARMACOTHERAPY, 2018,Volume: 101,Page: 334-341
Authors:  Wang, Anqi;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Gan, Lishe;  Lin, Ligen
View  |  Adobe PDF(1614Kb)  |  Favorite  |  View/Download:519/20  |  Submit date:2018/10/30
Physalin b  Breast Cancer  Cell Cycle  Apoptosis  P53  Akt  
Selective autophagy: The new player in the fight against neurodegenerative diseases? Journal article
BRAIN RESEARCH BULLETIN, 2018,Volume: 137,Page: 79-90
Authors:  Wu, Ming-Yue;  Song, Ju-Xian;  Wang, Sheng-Fang;  Cai, Cui-Zan;  Li, Min;  Lu, Jia-Hong
Favorite  |  View/Download:26/0  |  Submit date:2018/10/30
Selective Autophagy  Neurodegenerative Diesease  Aggrephagy  Chaperone-mediated Autophagy  Mitophagy  
Redox-sensitive micelles composed of disulfide-linked Pluronic-linoleic acid for enhanced anticancer efficiency of brusatol Journal article
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2018,Volume: 13,Page: 939-956
Authors:  Zhane, Jinming;  Fang, Xiaobin;  Li, Zeyong;  Chan, Hon Fai;  Lin, Zhixiu;  Wang, Yitao;  Chen, Meiwan
View  |  Adobe PDF(704Kb)  |  Favorite  |  View/Download:500/17  |  Submit date:2018/10/30
Poloxamer188  Tumor Micro-environment  Glutathione  Brucea Javanica  Cancer Treatment  
Codelivery of Doxorubicin and shAkt1 by Poly(ethylenimine)-Glycyrrhetinic Acid Nanoparticles to Induce Autophagy-Mediated Liver Cancer Combination Therapy Journal article
Molecular Pharmaceutics, 2016,Volume: 13,Issue: 4,Page: 1298-1307
Authors:  Wang F.-Z.;  Xing L.;  Tang Z.-H.;  Lu J.-J.;  Cui P.-F.;  Qiao J.-B.;  Jiang L.;  Jiang H.-L.;  Zong L.
Favorite  |  View/Download:4/0  |  Submit date:2018/12/28
Autophagy  Combination Therapy  Glycyrrhetinic Acid  Liver Cancer Targeting  Self-assembled