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Aurone derivatives as Vps34 inhibitors that modulate autophagy Journal article
ACTA PHARMACEUTICA SINICA B, 2019,Volume: 9,Issue: 3,Page: 537-544
Authors:  Guodong Li;  Joshua William Boyle;  Chung-Nga Ko;  Wu Zeng;  Vincent Kam Wai Wong;  Jian-Bo Wan;  Philip Wai Hong Chan;  Dik-Lung Ma;  Chung-Hang Leung
Favorite | View/Download:10/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2020/03/24
Autophagy  Natural Products  Vps34  Inhibitor  Structure-based Virtualscreening  Vesicle Trafficking  Heart Or Liver Damage  Aurone Derivative  
Baicalein Induces Beclin 1-and Extracellular Signal-Regulated Kinase-Dependent Autophagy in Ovarian Cancer Cells Journal article
AMERICAN JOURNAL OF CHINESE MEDICINE, 2017,Volume: 45,Issue: 1,Page: 123-136
Authors:  Wang, Ya-Fang;  Xu, Yu-Lian;  Tang, Zheng-Hai;  Li, Ting;  Zhang, Le-Le;  Chen, Xiuping;  Lu, Jia-Hong;  Leung, Chung-Hang;  Ma, Dik-Lung;  Qiang, Wen-An;  Wang, Yi-Tao;  Lu, Jin-Jian
Favorite | View/Download:26/0 | TC[WOS]:11 TC[Scopus]:0 | Submit date:2018/10/30
Baicalein  Ovarian Cancer  Autophagy  Beclin 1  Erk  
Autophagic degradation of epidermal growth factor receptor in gefitinib-resistant lung cancer by celastrol Journal article
International Journal of Oncology, 2016,Volume: 49,Issue: 4,Page: 1576-1588
Authors:  Xu S.-W.;  Law B.Y.K.;  Mok S.W.F.;  Leung E.L.H.;  Fan X.X.;  Coghi P.S.;  Zeng W.;  Leung C.-H.;  Ma D.-L.;  Liu L.;  Wong V.K.W.
Favorite | View/Download:9/0 | TC[WOS]:12 TC[Scopus]:0 | Submit date:2018/11/06
Autophagy  Calcium  Celastrol  Epidermal Growth Factor Receptor  Gefitinib-resistant Lung Cancer  
Cucurbitacin e induces caspase-dependent apoptosis and protective autophagy mediated by ROS in lung cancer cells Journal article
Chemico-Biological Interactions, 2016,Volume: 253,Page: 1
Authors:  Ma G.;  Luo W.;  Lu J.;  Ma D.-L.;  Leung C.-H.;  Wang Y.;  Chen X.
Favorite | View/Download:10/0 | TC[WOS]:23 TC[Scopus]:0 | Submit date:2018/10/31
Apoptosis  Autophagy  Cancer  Cucurbitacin e  Reactive Oxygen Species  
Isocryptotanshinone, a STAT3 inhibitor, induces apoptosis and pro-death autophagy in A549 lung cancer cells Journal article
Journal of Drug Targeting, 2016,Volume: 24,Issue: 10,Page: 934-942
Authors:  Shuhui Guo;  Weiwei Luo;  Lijuan Liu;  Xiaocong Pang;  Hong Zhu;  Ailin Liu;  Jinjian Lu;  Dik-Lung Ma;  Chung-Hang Leung;  Yitao Wang;  Xiuping Chen
Favorite | View/Download:10/0 | TC[WOS]:16 TC[Scopus]:0 | Submit date:2018/10/31
Apoptosis  Autophagy  Isocryptotanshinone  Stat3  
PTEN activation by DNA damage induces protective autophagy in response to Cucurbitacin B in hepatocellular carcinoma cells Journal article
Oxidative Medicine and Cellular Longevity, 2016,Volume: 2016
Authors:  Yanan Niu;  Wen Sun;  Jin-Jian Lu;  Dik-Lung Ma;  Chung-Hang Leung;  Lixia Pei;  Xiuping Chen
Favorite | View/Download:21/0 | TC[WOS]:10 TC[Scopus]:0 | Submit date:2018/11/06
Psoralidin induced reactive oxygen species (ROS)-dependent DNA damage and protective autophagy mediated by NOX4 in breast cancer cells Journal article
Phytomedicine, 2016,Volume: 23,Issue: 9,Page: 939
Authors:  Ren G.;  Luo W.;  Sun W.;  Niu Y.;  Ma D.-L.;  Leung C.-H.;  Wang Y.;  Lu J.-J.;  Chen X.
Favorite | View/Download:13/0 | TC[WOS]:18 TC[Scopus]:0 | Submit date:2018/10/31
Autophagy  Dna Damage  Nox4  Psoralidin  Ros  
Glycyrrhetinic acid induces cytoprotective autophagy via the inositol-requiring enzyme 1 alpha-c-Jun N-terminal kinase cascade in non-small cell lung cancer cells Journal article
ONCOTARGET, 2015,Volume: 6,Issue: 41,Page: 43911-43926
Authors:  Zheng-Hai Tang;  Le-Le Zhang;  Ting Li;  Jia-Hong Lu;  Dik-Lung Ma;  Chung-Hang Leung;  Xiu-Ping Chen;  Hu-Lin Jiang;  Yi-Tao Wang;  Jin-Jian Lu
Favorite | View/Download:4/0 | TC[WOS]:31 TC[Scopus]:0 | Submit date:2020/07/31
Glycyrrhetinic Acid  Autophagy  Jnk  Ire1 Alpha  Protective  
Total tanshinones-induced apoptosis and autophagy via reactive oxygen species in lung cancer 95D Cells Journal article
American Journal of Chinese Medicine, 2015,Volume: 43,Issue: 6,Page: 1265-1279
Authors:  Gao H.;  Sun W.;  Zhao W.;  Hao W.;  Leung C.-H.;  Lu J.;  Chen X.
Favorite | View/Download:6/0 | TC[WOS]:30 TC[Scopus]:0 | Submit date:2018/11/06
Apoptosis  Autophagy  Reactive Oxygen Species  Total Tanshinones  
Platycodin D induces apoptosis and triggers ERK- and JNK-mediated autophagy in human hepatocellular carcinoma BEL-7402 cells Journal article
Acta Pharmacologica Sinica, 2015,Volume: 36,Issue: 12,Page: 1503-1513
Authors:  Ting Li;  Xiao-huang Xu;  Zheng-hai Tang;  Ya-fang Wang;  Chung-hang Leung;  Dik-lung Ma;  Xiu-ping Chen;  Yi-tao Wang;  Yi Chen;  Jin-jian Lu
Favorite | View/Download:11/0 | TC[WOS]:27 TC[Scopus]:0 | Submit date:2018/10/31
Apoptosis  Autophagy  Erk  Baf  Bel-7402 Cells  Chloroquine  Human Hepatocellular Carcinoma  Jnk  Platycodin d  Sp600125  U0126