UM

Browse/Search Results:  1-6 of 6 Help

Filters    
Selected(0)Clear Items/Page:    Sort:
The discovery of AZD5597, a potent imidazole pyrimidine amide CDK inhibitor suitable for intravenous dosing Journal article
Bioorganic and Medicinal Chemistry Letters, 2008,Volume: 18,Issue: 24,Page: 6369-6373
Authors:  Jones C.D.;  Andrews D.M.;  Barker A.J.;  Blades K.;  Daunt P.;  East S.;  Geh C.;  Graham M.A.;  Johnson K.M.;  Loddick S.A.;  McFarland H.M.;  McGregor A.;  Moss L.;  Rudge D.A.;  Simpson P.B.;  Swain M.L.;  Tam K.Y.;  Tucker J.A.;  Walker M.
Favorite | View/Download:7/0 | TC[WOS]:32 TC[Scopus]:0 | Submit date:2018/12/18
Anti-cancer  Cdk  Cell Cycle  Cyclin-dependent Kinase  Imidazole Amide  Kinase  Kinase Inhibitor  
Synthesis and evaluation of heteroaryl-ketone derivatives as a novel class of VEGFR-2 inhibitors Journal article
Bioorganic and Medicinal Chemistry Letters, 2008,Volume: 18,Issue: 15,Page: 4344-4347
Authors:  Piatnitski Chekler E.L.;  Katoch-Rouse R.;  Kiselyov A.S.;  Sherman D.;  Ouyang X.;  Kim K.;  Wang Y.;  Hadari Y.R.;  Doody J.F.
Favorite | View/Download:5/0 | TC[WOS]:9 TC[Scopus]:0 | Submit date:2019/01/16
Angiogenesis  Kinase inhibitor  Vascular endothelial growth factor  
Novel tricyclic azepine derivatives: Biological evaluation of pyrimido[4,5-b]-1,4-benzoxazepines, thiazepines, and diazepines as inhibitors of the epidermal growth factor receptor tyrosine kinase Journal article
Bioorganic and Medicinal Chemistry Letters, 2006,Volume: 16,Issue: 19,Page: 5102-5106
Authors:  Smith II L.;  Wong W.C.;  Kiselyov A.S.;  Burdzovic-Wizemann S.;  Mao Y.;  Xu Y.;  Duncton M.A.J.;  Kim K.;  Piatnitski E.L.;  Doody J.F.;  Wang Y.;  Rosler R.L.;  Milligan D.;  Columbus J.;  Balagtas C.;  Lee S.P.;  Konovalov A.;  Hadari Y.R.
Favorite | View/Download:2/0 | TC[WOS]:29 TC[Scopus]:0 | Submit date:2019/01/16
Diazepine  Epidermal growth factor receptor  Kinase inhibitor  Oxazepine  Thiazepine  
Tricyclic azepine derivatives: Pyrimido[4,5-b]-1,4-benzoxazepines as a novel class of epidermal growth factor receptor kinase inhibitors Journal article
Bioorganic and Medicinal Chemistry Letters, 2006,Volume: 16,Issue: 6,Page: 1643-1646
Authors:  Smith II L.;  Piatnitski E.L.;  Kiselyov A.S.;  Ouyang X.;  Chen X.;  Burdzovic-Wizemann S.;  Xu Y.;  Wang Y.;  Rosler R.L.;  Patel S.N.;  Chiang H.-H.;  Milligan D.L.;  Columbus J.;  Wong W.C.;  Doody J.F.;  Hadari Y.R.
Favorite | View/Download:6/0 | TC[WOS]:18 TC[Scopus]:0 | Submit date:2019/01/16
Benzoxazepine  Epidermal growth factor receptor  Kinase inhibitor  Kinase selectivity  
Oxadiazole derivatives as a novel class of antimitotic agents: Synthesis, inhibition of tubulin polymerization, and activity in tumor cell lines Journal article
Bioorganic and Medicinal Chemistry Letters, 2006,Volume: 16,Issue: 5,Page: 1191-1196
Authors:  Ouyang X.;  Piatnitski E.L.;  Pattaropong V.;  Chen X.;  He H.-Y.;  Kiselyov A.S.;  Velankar A.;  Kawakami J.;  Labelle M.;  Smith II L.;  Lohman J.;  Lee S.P.;  Malikzay A.;  Fleming J.;  Gerlak J.;  Wang Y.;  Rosler R.L.;  Zhou K.;  Mitelman S.;  Camara M.;  Surguladze D.;  Doody J.F.;  Tuma M.C.
Favorite | View/Download:4/0 | TC[WOS]:75 TC[Scopus]:0 | Submit date:2019/01/16
1,3,4-Oxadiazole  Antimitotic agent  Multiple-drug resistance  Tubulin polymerization inhibitor  
Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors Journal article
Bioorganic and Medicinal Chemistry Letters, 2005,Volume: 15,Issue: 23,Page: 5154-5159
Authors:  Ouyang X.;  Chen X.;  Piatnitski E.L.;  Kiselyov A.S.;  He H.-Y.;  Mao Y.;  Pattaropong V.;  Yu Y.;  Kim K.H.;  Kincaid J.;  Smith II L.;  Wong W.C.;  Lee S.P.;  Milligan D.L.;  Malikzay A.;  Fleming J.;  Gerlak J.;  Deevi D.;  Doody J.F.;  Chiang H.-H.;  Patel S.N.;  Wang Y.;  Rolser R.L.;  Kussie P.;  Labelle M.;  Tuma M.C.
Favorite | View/Download:3/0 | TC[WOS]:54 TC[Scopus]:0 | Submit date:2019/01/16
1,2,4-Triazole  Antimitotic  Tubulin inhibitor  Tubulin polymerization  Tumor vasculature  Vascular disrupting agent