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Yinchenhao Decoction Alleviates Liver Fibrosis by Regulating Bile Acid Metabolism and TGF-β/Smad/ERK Signalling Pathway Journal article
Scientific Reports, 2018,Volume: 8,Issue: 1
Authors:  Cai F.-F.;  Wu R.;  Song Y.-N.;  Xiong A.-Z.;  Chen X.-L.;  Yang M.-D.;  Yang L.;  Hu Y.;  Sun M.-Y.;  Su S.-B.
Favorite  |  View/Download:19/0  |  Submit date:2018/12/28
Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships Journal article
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018,Volume: 28,Issue: 21,Page: 3441-3445
Authors:  Zhang, Shao-Lin;  Yang, Zheng;  Hu, Xiaohui;  Tam, Kin Yip
Favorite  |  View/Download:17/0  |  Submit date:2018/10/30
Pyruvate dehydrogenase kinase  Pyruvate dehydrogenase complex  Antiproliferative activity  Dichloroacetophenone  Kinase inhibition  
Selective Inhibition of Lysine-Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple-Negative Breast Cancer Therapy Journal article
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018,Volume: 57,Issue: 40,Page: 13091-13095
Authors:  Yang, Guan-Jun;  Wang, Wanhe;  Mok, Simon Wing Fai;  Wu, Chun;  Law, Betty Yuen Kwan;  Miao, Xiang-Min;  Wu, Ke-Jia;  Zhong, Hai-Jing;  Wong, Chun-Yuen;  Wong, Vincent Kam Wai;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite  |  View/Download:39/0  |  Submit date:2018/10/30
Drug Discovery  Epigenetics  Medicinal Chemistry  Triple-negative Breast Cancer  
Gallic acid, a natural polyphenol, protects against tert-butyl hydroperoxide- induced hepatotoxicity by activating ERK-Nrf2-Keap1-mediated antioxidative response Journal article
Food and Chemical Toxicology, 2018,Volume: 119,Page: 479-488
Authors:  Feng R.-B.;  Wang Y.;  He C.;  Yang Y.;  Wan J.-B.
Favorite  |  View/Download:6/0  |  Submit date:2018/12/28
Gallic Acid  Nuclear Factor Erythroid 2-related Factor 2  Oxidative Stress  Tert-butyl Hydroperoxide  
Anti-cancer effects of Rhizoma Curcumae against doxorubicin-resistant breast cancer cells Journal article
CHINESE MEDICINE, 2018,Volume: 13
Authors:  Zhong, Zhangfeng;  Yu, Haibing;  Wang, Shengpeng;  Wang, Yitao;  Cui, Liao
View  |  Adobe PDF(2911Kb)  |  Favorite  |  View/Download:533/19  |  Submit date:2018/10/30
Rhizoma Curcumae  Multidrug Resistance  Breast Cancer  Abc Transporters  Furanodiene  
Periplaneta americana Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Rats by Keap1/Nrf-2 Activation, Intestinal Barrier Function, and Gut Microbiota Regulation Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Ma, Xuewei;  Hu, Yichen;  Li, Xin;  Zheng, Xiaoting;  Wang, Yitao;  Zhang, Jinming;  Fu, Chaomei;  Geng, Funeng
View  |  Adobe PDF(4337Kb)  |  Favorite  |  View/Download:902/19  |  Submit date:2018/10/30
Ulcerative Colitis  Periplaneta Americana  16s Rrna  Gut Microbiota  Intestinal Immunity  
Ponatinib exerts anti-angiogenic effects in the zebrafish and human umbilical vein endothelial cells via blocking VEGFR signaling pathway Journal article
Oncotarget, 2018,Volume: 9,Issue: 62,Page: 31958-31970
Authors:  Nana Ai;  Cheong-Meng Chong.;  Weiting Chen;  Zhe Hu;  Huanxing Su;  Guokai Chen;  Queenie Wing Lei Wong;  Wei Ge
Favorite  |  View/Download:14/0  |  Submit date:2018/12/11
Angiogenesis  Enos  Huvec  Mapk  Ponatinib  
A novel Ca2+ current blocker promotes angiogenesis and cardiac healing after experimental myocardial infarction in mice Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 134,Page: 109-117
Authors:  Cui, Guozhen;  Xin, Qiqi;  Tseng, Hisa Hui Ling;  Hoi, Maggie PuiMan;  Wang, Yan;  Yang, Binrui;  Choi, InLeng;  Wang, Yuqiang;  Yuan, Rong;  Chen, Keji;  Cong, Weihong;  Lee, Simon MingYuen
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Cardioprotection  Angiogenesis  ADTM  Zebrafish  VEGF  
Laboratory Evaluation and Mechanistic Understanding of the Impact of Ferric Species on Oilfield Scale Inhibitor Performance Journal article
ENERGY & FUELS, 2018,Volume: 32,Issue: 8,Page: 8348-8357
Authors:  Zhang, Zhang;  Zhang, Ping;  Li, Zhejun;  Kan, Amy T.;  Tomson, Mason B.
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The p38 MaPK inhibitor sB203580 abrogates Tumor necrosis Factor-induced Proliferative expansion of Mouse cD4(+)Foxp3(+) regulatory T cells Journal article
FRONTIERS IN IMMUNOLOGY, 2018,Volume: 9
Authors:  He, Tianzhen;  Liu, Shuoyang;  Chen, Shaokui;  Ye, Jingyi;  Wu, Xueqiang;  Bian, Zhaoxiang;  Chen, Xin
Favorite  |  View/Download:20/0  |  Submit date:2018/10/30
tumor necrosis factor  TNF receptor type II  p38 MAPK  CD4(+)Foxp3(+) regulatory T cells  proliferation