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Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
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Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
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Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Diethyl blechnic, a novel natural product isolated from salvia miltiorrhiza bunge, inhibits doxorubicin-induced apoptosis by inhibiting ROS and activating JNK1/2 Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 6
Authors:  Yu J.;  Gao H.;  Wu C.;  Xu Q.-M.;  Lu J.-J.;  Chen X.
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Cardiotoxicity  Diethyl Blechnic  Dox  Jnk1/2  Ros  
Increased expression of IRE1α associates with the resistant mechanism of osimertinib (AZD9291)-resistant non-small cell lung cancer HCC827/OSIR cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2018,Volume: 18,Issue: 4,Page: 550-555
Authors:  Tang Z.-H.;  Su M.-X.;  Guo X.;  Jiang X.-M.;  Jia L.;  Chen X.;  Lu J.-J.
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Azd9291  Egfr  Ire1α  Lune Cancer  Nsclc  Osimertinib  
2-methoxy-6-acetyl-7-methyljuglone (MAM) induces iNOS/NO-mediated DNA damage response through activation of MAPKs pathways Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2018,Volume: 18,Issue: 6,Page: 903-913
Authors:  Niu Y.;  Yuan R.;  Gao H.;  Lu J.-J.;  Kong Q.;  Chen X.
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Atm/chk2  Dna Damage  Inos/no  L-arginine  Mam  Mapks  
Identification of a novel autophagic inhibitor cepharanthine to enhance the anti-cancer property of dacomitinib in non-small cell lung cancer Journal article
CANCER LETTERS, 2018,Volume: 412,Page: 1-9
Authors:  Tang, Zheng-Hai;  Cao, Wen-Xiang;  Guo, Xia;  Dai, Xiao-Yang;  Lu, Jia-Hong;  Chen, Xiuping;  Zhu, Hong;  Lu, Jin-Jian
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Cepharanthine  Autophagy  Lysosome  Dacomitinib  Nsclc  
Osimertinib resistance in non-small cell lung cancer: Mechanisms and therapeutic strategies Journal article
CANCER LETTERS, 2018,Volume: 420,Page: 242-246
Authors:  Tang, Zheng-Hai;  Lu, Jin-Jian
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Osimertinib  Azd9291  Egfr Tki  Resistant Mechanisms  Therapeutic Strategies  
Baicalein protects tert-butyl hydroperoxide-induced hepatotoxicity dependent of reactive oxygen species removal Journal article
MOLECULAR MEDICINE REPORTS, 2017,Volume: 16,Issue: 6,Page: 8392-8398
Authors:  Wang, Ya-Fang;  Tang, Zheng-Hai;  Li, Ting;  Xu, Xiao-Huang;  Chen, Xiuping;  Wang, Ying;  Wang, Yi-Tao;  Lu, Jin-Jian
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Baicalein  Liver Protection  Reactive Oxygen Species  Apoptosis  
Osimertinib (AZD9291) decreases programmed death ligand-1 in EGFR-mutated non-small cell lung cancer cells Journal article
ACTA PHARMACOLOGICA SINICA, 2017,Volume: 38,Issue: 11,Page: 1512-1520
Authors:  Jiang, Xiao-Ming;  Xu, Yu-Lian;  Huang, Mu-Yang;  Zhang, Le-Le;  Su, Min-Xia;  Chen, Xiuping;  Lu, Jin-Jian
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Non-small Cell Lung Cancer  Egfr  Osimertinib  Pd-l1  Ubiquitin-proteasome System  Mg-132  Bortezomib  Gsk3 Beta  Licl  
Garcinone E induces apoptosis and inhibits migration and invasion in ovarian cancer cells Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Xu, Xiao-Huang;  Liu, Qian-Yu;  Li, Ting;  Liu, Jian-Lin;  Chen, Xin;  Huang, Li;  Qiang, Wen-An;  Chen, Xiuping;  Wang, Yitao;  Lin, Li-Gen;  Lu, Jin-Jian
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