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Phytochemicals, pharmacology, clinical application, patents, and products of Amomi fructus Conference paper
Authors:  Suo, Sizhuo;  Lai, Yunfeng;  Li, Meng;  Song, Qirui;  Cai, Jing;  Zhao, Jing;  Yang, Qing;  Ung, Carolina Oi Lam;  Hu, Hao
Favorite  |  View/Download:22/0  |  Submit date:2018/10/30
Phytochemicals  Pharmacology  Clinical application  Patents and products  Amomi fructus  
Synthesis and biological evaluation of (R)-3,3,3-trifluoro-2-hydroxy-2methylpropionamides as pyruvate dehydrogenase kinase 1 (PDK1) inhibitors to reduce the growth of cancer cells Conference paper
Authors:  Zhang, Shao-Lin;  Zhang, Wen;  Yang, Zheng;  Hu, Xiaohui;  Tam, Kin Yip
Favorite  |  View/Download:6/0  |  Submit date:2018/10/30
Pyruvate dehydrogenase kinase  Pyruvate dehydrogenase complex  Anti-proliferation  Binding affinity  
SLM, a novel carbazole-based fluorophore attenuates okadaic acid-induced tau hyperphosphorylation via down-regulating GSK-3 beta activity in SH-SY5Y cells Conference paper
Authors:  Wu, Xiaoli;  Kosaraju, Jayasankar;  Tam, Kin Yip
Favorite  |  View/Download:4/0  |  Submit date:2018/10/30
Tau hyperphosphorylation  Alzheimer's disease  SLM  Okadaic acid  Glycogen synthase kinase-3 beta  
Phenyl butyrate inhibits pyruvate dehydrogenase kinase 1 and contributes to its anti-cancer effect Conference paper
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, Zhuhai, PEOPLES R CHINA, 2016-8-23-26
Authors:  Zhang, Wen;  Zhang, Shao-Lin;  Hu, Xiaohui;  Tam, Kin Yip
Favorite  |  View/Download:15/0  |  Submit date:2018/10/30
Phenyl Butyrate  Cancer  Pyruvate Dehydrogenase  Pyruvate Dehydrogenase Kinase 1  Tumor Metabolism  
Anti-tumor effects of a 'human & mouse cross-reactive' anti-ADAM17 antibody in a pancreatic cancer model in vivo Conference paper
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, Zhuhai, PEOPLES R CHINA, AUG 23-26, 2016
Authors:  Ye, Jie;  Yuen, Shun Ming;  Murphy, Gillian;  Xie, Ruiyu;  Kwok, Hang Fai
Favorite  |  View/Download:16/0  |  Submit date:2018/10/31
Pancreatic Ductal Adenocarcinoma (Pdac)  Adam17  Inhibitory Antibody  Tumorigenesis  Targeted Therapy  
The effects and mechanisms of two main constituents from Glycyrrhiza uralensis Fisch-induced autophagy in non-small cell lung cancer Conference paper
BIOCHEMICAL PHARMACOLOGY, Aberdeen, SCOTLAND, SEP 27-29, 2017
Authors:  Tang, Zheng-Hai;  Zhang, Le-Le;  Chen, Xin;  Chen, Xiuping;  Wang, Yitao;  Lu, Jin-Jian
Favorite  |  View/Download:15/0  |  Submit date:2018/10/30
Oxidative stress induced both apoptosis and necroptosis in endothelial cells Conference paper
Authors:  Chen, Xiuping;  Zhao, Wenwen
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MAM, a natural naphthoquinone, induces necroptosis in cancer cells Conference paper
Authors:  Chen, Xiuping;  Sun, Wen
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Modulation of macrophage behavior with glucomannan polymers for cancer immunotherapy and bone regeneration Conference paper
4th Symposium on Innovative Polymers for Controlled Delivery (SIPCD 2016), Suzhou, China, 2016
Authors:  Niu, Yiming;  Feng, Yanxian;  Wang, Chunming
Favorite  |  View/Download:26/0  |  Submit date:2018/10/30
Glucomannan  C-type Lectins  Macrophage  Immunotherapy  Bone Regeneration  
Sequestering of PDGF-BB and FGF-2 with an acidic polysaccharide for in situ vascularization Conference paper
JOURNAL OF CONTROLLED RELEASE, Suzhou, China, 23–26 September 2016
Authors:  Li, Qiu;  Niu, Yiming;  Wang, Chunming
Favorite  |  View/Download:24/0  |  Submit date:2018/10/30
Polysaccharide  Growth Factors  Bio-responsive  Therapeutic Angiogenesis