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Furanodiene Induces Extrinsic and Intrinsic Apoptosis in Doxorubicin-Resistant MCF-7 Breast Cancer Cells via NF-kappa B-Independent Mechanism (vol 8, 648, 2017) Journal article
FRONTIERS IN PHARMACOLOGY, 2017,Volume: 8
Authors:  Zhong, Zhang-Feng;  Yu, Hai-Bing;  Wang, Chun-Ming;  Qiang, Wen-An;  Wang, Sheng-Peng;  Zhang, Jin-Ming;  Yu, Hua;  Cui, Liao;  Wu, Tie;  Li, De-Qiang;  Wang, Yi-Tao
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Furanodiene  Multidrug Resistance  Breast Cancer  Cell Apoptosis  Intrinsic/extrinsic Apoptosis  Nf-kappa b  
Synthesis and biological evaluation of (R)-3,3,3-trifluoro-2-hydroxy-2methylpropionamides as pyruvate dehydrogenase kinase 1 (PDK1) inhibitors to reduce the growth of cancer cells Conference paper
Authors:  Zhang, Shao-Lin;  Zhang, Wen;  Yang, Zheng;  Hu, Xiaohui;  Tam, Kin Yip
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Pyruvate dehydrogenase kinase  Pyruvate dehydrogenase complex  Anti-proliferation  Binding affinity  
SLM, a novel carbazole-based fluorophore attenuates okadaic acid-induced tau hyperphosphorylation via down-regulating GSK-3 beta activity in SH-SY5Y cells Conference paper
Authors:  Wu, Xiaoli;  Kosaraju, Jayasankar;  Tam, Kin Yip
Favorite  |  View/Download:4/0  |  Submit date:2018/10/30
Tau hyperphosphorylation  Alzheimer's disease  SLM  Okadaic acid  Glycogen synthase kinase-3 beta  
Phenyl butyrate inhibits pyruvate dehydrogenase kinase 1 and contributes to its anti-cancer effect Conference paper
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, Zhuhai, PEOPLES R CHINA, 2016-8-23-26
Authors:  Zhang, Wen;  Zhang, Shao-Lin;  Hu, Xiaohui;  Tam, Kin Yip
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Phenyl Butyrate  Cancer  Pyruvate Dehydrogenase  Pyruvate Dehydrogenase Kinase 1  Tumor Metabolism  
Geniposide improves insulin production and reduces apoptosis in high glucose-induced glucotoxic insulinoma cells Journal article
European Journal of Pharmaceutical Sciences, 2017,Volume: 110,Page: 70-76
Authors:  Guo L.X.;  Liu J.H.;  Zheng X.X.;  Yin Z.Y.;  Kosaraju J.;  Tam K.Y.
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Apoptosis  Geniposide  Glucose-stimulated Insulin Secretion  Glucotoxicity  
SLM, a novel carbazole-based fluorophore attenuates okadaic acid-induced tau hyperphosphorylation via down-regulating GSK-3β activity in SH-SY5Y cells Journal article
European Journal of Pharmaceutical Sciences, 2017,Volume: 110,Page: 101-108
Authors:  Wu X.;  Kosaraju J.;  Tam K.Y.
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Alzheimer's Disease  Glycogen Synthase Kinase-3β  Okadaic Acid  Slm  Tau Hyperphosphorylation  
Editorial, IAPC-5 Special Issue Journal article
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2017,Volume: 110,Page: 1-1
Authors:  Mandic, Zoran;  Tam, Kin
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Anti-tumor effects of a 'human & mouse cross-reactive' anti-ADAM17 antibody in a pancreatic cancer model in vivo Conference paper
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, Zhuhai, PEOPLES R CHINA, AUG 23-26, 2016
Authors:  Ye, Jie;  Yuen, Shun Ming;  Murphy, Gillian;  Xie, Ruiyu;  Kwok, Hang Fai
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Pancreatic Ductal Adenocarcinoma (Pdac)  Adam17  Inhibitory Antibody  Tumorigenesis  Targeted Therapy  
Anti-tumor effects of a ‘human & mouse cross-reactive’ anti-ADAM17 antibody in a pancreatic cancer model in vivo Journal article
European Journal of Pharmaceutical Sciences, 2017,Volume: 110,Page: 62-69
Authors:  Ye J.;  Yuen S.M.;  Murphy G.;  Xie R.;  Kwok H.F.
Favorite  |  View/Download:11/0  |  Submit date:2018/12/19
Adam17  Inhibitory Antibody  Pancreatic Ductal Adenocarcinoma (Pdac)  Targeted Therapy  Tumorigenesis  
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview Journal article
British Journal of Pharmacology, 2017,Volume: 174,Page: S1-S16
Authors:  Alexander S.P.H.;  Kelly E.;  Marrion N.V.;  Peters J.A.;  Faccenda E.;  Harding S.D.;  Pawson A.J.;  Sharman J.L.;  Southan C.;  Buneman O.P.;  Cidlowski J.A.;  Christopoulos A.;  Davenport A.P.;  Fabbro D.;  Spedding M.;  Striessnig J.;  Davies J.A.;  Abbracchio M.-P.;  Aldrich R.;  Al-Hosaini K.;  Arumugam T.V.;  Attali B.;  Back M.;  Barnes N.M.;  Bathgate R.;  Beart P.M.;  Becirovic E.;  Bettler B.;  Biel M.;  Birdsall N.J.;  Blaho V.;  Boison D.;  Brauner-osborne H.;  Broer S.;  Bryant C.;  Burnstock G.;  Calo G.;  Catterall W.A.;  Ceruti S.;  Chan S.L.;  Chandy K.G.;  Chazot P.;  Chiang N.;  Chun J.J.;  Chung J.-J.;  Clapham D.E.;  Clapp L.;  Connor M.A.;  Cox H.M.;  Davies P.;  Dawson P.A.;  Decaen P.;  Dent G.;  Doherty P.;  Douglas S.D.;  Dubocovich M.L.;  Fong T.M.;  Fowler C.J.;  Frantz A.;  Fuller P.;  Fumagalli M.;  Futerman A.H.;  Gainetdinov R.R.;  Gershengorn M.A.;  Goldin A.;  Goldstein S.A.N.;  Goudet C.;  Gregory K.;  Grissmer S.;  Gundlach A.L.;  Hagenbuch B.;  Hamann J.;  Hammond J.R.;  Hancox J.C.;  Hanson J.;  Hanukoglu I.;  Hay D.L.;  Hobbs A.J.;  Hollenberg A.N.;  Holliday N.D.;  Hoyer D.;  Ijzerman A.P.;  Inui K.I.;  Irving A.J.;  Ishii S.;  Jacobson K.A.;  Jan L.Y.;  Jarvis M.F.;  Jensen R.;  Jockers R.;  Kaczmarek L.K.;  Kanai Y.;  Karnik S.;  Kellenberger S.;  Kemp S.;  Kennedy C.;  Kerr I.D.;  Kihara Y.;  Kukkonen J.;  Larhammar D.;  Leach K.;  Lecca D.;  Leeman S.;  Leprince J.;  Lolait S.J.;  Macewan D.;  Maguire J.J.;  Marshall F.;  Mazella J.;  Mcardle C.A.;  Michel M.C.;  Miller L.J.;  Mitolo V.;  Mizuno H.;  Monk P.N.;  Mouillac B.;  Murphy P.M.;  Nahon J.-L.;  Nerbonne J.;  Nichols C.G.;  Norel X.;  Offermanns S.;  Palmer L.G.;  Panaro M.A.;  Papapetropoulos A.;  Perez-reyes E.;  Pertwee R.G.;  Pintor S.;  Pisegna J.R.;  Plant L.D.;  Poyner D.R.;  Prossnitz E.R.;  Pyne S.;  Ramachandran R.;  Ren D.;  Rondard P.;  Ruzza C.;  Sackin H.;  Sanger G.;  Sanguinetti M.C.;  Schild L.;  Schioth H.;  Schulte G.;  Schulz S.;  Segaloff D.L.;  Serhan C.N.;  Singh K.D.;  Slesinger P.A.;  Snutch T.P.;  Sobey C.G.;  Stewart G.;  Stoddart L.A.;  Summers R.J.;  Szabo C.;  Thwaites D.;  Toll L.;  Trimmer J.S.;  Tucker S.;  Vaudry H.;  Verri T.;  Vilargada J.-P.;  Waldman S.A.;  Ward D.T.;  Waxman S.G.;  Wei A.D.;  Willars G.B.;  Wong S.S.;  Woodruff T.M.;  Wulff H.;  Ye R.D.;  Yung Y.;  Zajac J.-M.
Favorite  |  View/Download:20/0  |  Submit date:2018/11/07