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A Comprehensive Map of FDA-Approved Pharmaceutical Products Journal article
PHARMACEUTICS, 2018,Volume: 10,Issue: 4
Authors:  Hao Zhong;  Ging Chan;  Yuanjia Hu;  Hao Hu;  Defang Ouyang
Favorite  |  View/Download:14/0  |  Submit date:2020/01/06
Drug Delivery System  Fda-approval Drugs  Generic Drugs  Oral Sustained-release Preparation  Inhalation  Complex Injection  Transdermal Patch  
Fighting Liver Fibrosis with Naturally Occurring Antioxidants Journal article
PLANTA MEDICA, 2018,Volume: 84,Issue: 18,Page: 1318-1333
Authors:  Lin, Ligen;  Zhou, Fayang;  Shen, Shengnan;  Zhang, Tian
Favorite  |  View/Download:12/0  |  Submit date:2019/01/17
Liver Fibrosis  Antioxidants  Oxidative Stress  Reactive Oxygen Species  Hepatic Stellate Cells  Natural Products  
Trends of Polypharmacy and Prescription Patterns of Antidepressants in Asia Journal article
JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 2018,Volume: 38,Issue: 6,Page: 598-603
Authors:  Huang, Cho-Yin;  Yang, Shu-Yu;  Mojtabai, Ramin;  Lin, Shu-Ku;  He, Yan-Ling;  Chong, Mian-Yoon;  Ungvari, Gabor;  Tan, Chay-Hoon;  Xiang, Yu-Tao;  Sartorius, Norman;  Shinfuku, Naotaka;  Chen, Lian-Yu
Favorite  |  View/Download:32/0  |  Submit date:2019/01/17
Antidepressant Use  Polypharmacy  Prescription Pattern  
Resveratrol ameliorates endothelial dysfunction in diabetic and obese mice through sirtuin 1 and peroxisome proliferator-activated receptor delta Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 139,Page: 384-394
Authors:  Wai San Cheang;  Wing Tak Wong;  Li Wang;  Chak Kwong Cheng;  Chi Wai Lau;  Ronald Chin Wan Ma;  Aimin Xu;  Nanping Wang;  Yu Huang;  Xiao Yu Tian
Favorite  |  View/Download:13/0  |  Submit date:2020/04/09
Pparδ  Sirt1  Endothelial Dysfunction  Diet Induced Obesity  
Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships Journal article
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018,Volume: 28,Issue: 21,Page: 3441-3445
Authors:  Zhang, Shao-Lin;  Yang, Zheng;  Hu, Xiaohui;  Tam, Kin Yip
Favorite  |  View/Download:17/0  |  Submit date:2018/10/30
Pyruvate dehydrogenase kinase  Pyruvate dehydrogenase complex  Antiproliferative activity  Dichloroacetophenone  Kinase inhibition  
Identification of Novel Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors by Kinase Activity-Based High-Throughput Screening for Anticancer Therapeutics Journal article
ACS Combinatorial Science, 2018,Volume: 20,Issue: 11,Page: 660-671
Authors:  Zhang W.;  Hu X.;  Chakravarty H.;  Yang Z.;  Tam K.Y.
Favorite  |  View/Download:18/0  |  Submit date:2018/12/18
cancer  high-throughput screening  pyruvate dehydrogenase kinase 1  small molecule inhibitors  Warburg effect  
Inhibition of pyruvate dehydrogenase kinase 1 enhances the anti-cancer effect of EGFR tyrosine kinase inhibitors in non-small cell lung cancer Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 838,Page: 41-52
Authors:  Yang, Zheng;  Zhang, Shao-Lin;  Hu, Xiaohui;  Tam, Kin Yip
Favorite  |  View/Download:28/0  |  Submit date:2018/10/30
Dichloroacetophenone  Epidermal Growth Factor Receptor  Tyrosine Kinase Inhibitor  Synergism  Hypoxia  Oxidative Phosphorylation  
Editorial, IAPC-6 Meeting Journal article
PHARMACEUTICAL RESEARCH, 2018,Volume: 35,Issue: 11
Authors:  Tam, Kin;  Li, Tonglei;  Mandic, Zoran
Favorite  |  View/Download:5/0  |  Submit date:2019/01/17
Anticancer effects of some novel dichloroacetophenones through the inhibition of pyruvate dehydrogenase kinase 1 Journal article
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2018,Volume: 123,Page: 43-55
Authors:  Zhang, Shao-Lin;  Yang, Zheng;  Hu, Xiaohui;  Chakravarty, Harapriya;  Tam, Kin Yip
Favorite  |  View/Download:22/0  |  Submit date:2018/10/30
Dichloroacetophenone  Pyruvate Dehydrogenase Kinase  Pyruvate Dehydrogenase Complex  Anticancer Activity  Metabolic Reprogramming  
Internationalization of Traditional/Complementary Medicine products: market entry as medicine Journal article
CHINESE MEDICINE, 2018,Volume: 13
Authors:  Li, Jiatong;  Zhu, Jianfan;  Hu, Hao;  Harnett, Joanna E.;  Lei, Chi Ieong;  Chau, Ka Yin;  Chan, Ging;  Ung, Carolina Oi Lam
View  |  Adobe PDF(933Kb)  |  Favorite  |  View/Download:490/10  |  Submit date:2018/10/30
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