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Anti-inflammatory activities of Sigesbeckia glabrescens Makino: combined in vitro and in silico investigations Journal article
CHINESE MEDICINE, 2019,Volume: 14,Issue: 1
Authors:  Zhangfeng Zhong;  Qianru Zhang;  Hongxun Tao;  Wei Sang;  Liao Cui;  Wenan Qiang;  Wai San Cheang;  Yuanjia Hu;  Hua Yu;  Yitao Wang
Favorite  |  View/Download:64/0  |  Submit date:2019/11/22
Sigesbeckia Glabrescens Makino  Infammation  Lipopolysaccharide  Docking  Tlr4  Nf-κb  
Discovery of fused bicyclic derivatives of 1H-pyrrolo[1,2-c]imidazol-1-one as VDR signaling regulators Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2019,Volume: 27,Issue: 17,Page: 3879-3888
Authors:  Bin Xu;  Mo-Yu Ding;  Zhibing Weng;  Zheng-Qing Li;  Feng Li;  Xia Sun;  Qiu-Ling Chen;  Yi-Tao Wang;  Ying Wang;  Guo-Chun Zhou
Favorite  |  View/Download:30/0  |  Submit date:2019/11/22
1h-pyrrolo[1,2-c]Imidazol-1-one  Vitamin d Receptor (Vdr)  Autophagy  Apoptosis  
Chemistry, pharmacology and analysis of Pseudostellaria heterophylla: a mini-review Journal article
CHINESE MEDICINE, 2019,Volume: 14
Authors:  De‑jun Hu;  Farid Shakerian;  Jing Zhao;  Shao‑Ping Li
Favorite  |  View/Download:23/0  |  Submit date:2019/11/22
Pseudostellaria Heterophylla  Chemistry  Pharmacology  Analysis  
An Integrated Transfer Learning and Multitask Learning Approach for Pharmacokinetic Parameter Prediction Journal article
Molecular Pharmaceutics, 2019,Volume: 16,Issue: 2,Page: 533-541
Authors:  Ye Z.;  Yang Y.;  Li X.;  Cao D.;  Ouyang D.
Favorite  |  View/Download:19/0  |  Submit date:2019/02/14
Adme  Deep Learning  Multitask Learning  Pharmacokinetic Parameters  Transfer Learning  
γ-Mangostin alleviates liver fibrosis through Sirtuin 3-superoxide-high mobility group box 1 signaling axis Journal article
Toxicology and Applied Pharmacology, 2019,Volume: 363,Page: 142-153
Authors:  Wang A.;  Zhou F.;  Li D.;  Lu J.-J.;  Wang Y.;  Lin L.
Favorite  |  View/Download:20/0  |  Submit date:2018/12/28
Fibrogenesis  Hmgb1  Liver Fibrosis  Sirtuin 3  Superoxide  Γ-mangostin  
Comparative comprehension on the anti-rheumatic Chinese herbal medicine Siegesbeckiae Herba: Combined computational predictions and experimental investigations Journal article
Journal of Ethnopharmacology, 2019,Volume: 228,Page: 200-209
Authors:  Zhang Q.R.;  Zhong Z.F.;  Sang W.;  Xiong W.;  Tao H.X.;  Zhao G.D.;  Li Z.X.;  Ma Q.S.;  Tse A.K.W.;  Hu Y.J.;  Yu H.;  Wang Y.T.
Favorite  |  View/Download:28/0  |  Submit date:2018/12/28
Computational Prediction  Difference  Rheumatoid Arthritis  Siegesbeckiae Herba  Similarity  
Deep learning for in vitro prediction of pharmaceutical formulations Journal article
Acta Pharmaceutica Sinica B, 2019,Volume: 9,Issue: 1,Page: 177-185
Authors:  Yang Y.;  Ye Z.;  Su Y.;  Zhao Q.;  Li X.;  Ouyang D.
Favorite  |  View/Download:12/0  |  Submit date:2019/02/14
Automatic Dataset Selection Algorithm  Deep Learning  Oral Fast Disintegrating Films  Oral Sustained Release Matrix Tablets  Pharmaceutical Formulation  Small Data  
Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships Journal article
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018,Volume: 28,Issue: 21,Page: 3441-3445
Authors:  Zhang, Shao-Lin;  Yang, Zheng;  Hu, Xiaohui;  Tam, Kin Yip
Favorite  |  View/Download:17/0  |  Submit date:2018/10/30
Pyruvate dehydrogenase kinase  Pyruvate dehydrogenase complex  Antiproliferative activity  Dichloroacetophenone  Kinase inhibition  
Internationalization of Traditional/Complementary Medicine products: market entry as medicine Journal article
CHINESE MEDICINE, 2018,Volume: 13
Authors:  Li, Jiatong;  Zhu, Jianfan;  Hu, Hao;  Harnett, Joanna E.;  Lei, Chi Ieong;  Chau, Ka Yin;  Chan, Ging;  Ung, Carolina Oi Lam
View  |  Adobe PDF(933Kb)  |  Favorite  |  View/Download:490/10  |  Submit date:2018/10/30
Traditional Chinese Medicines  Chinese Patent Medicines  Proprietary Chinese Medicines  Traditional And Complementary Medicine  Registration  Internationalization  Quality  Safety  Efficacy  
Studies on aminoglycoside susceptibility identify a novel function of KsgA to secure translational fidelity during antibiotic stress Journal article
Antimicrobial Agents and Chemotherapy, 2018,Volume: 62,Issue: 10
Authors:  Zou J.;  Zhang W.;  Zhang H.;  Zhang X.D.;  Peng B.;  Zheng J.
Favorite  |  View/Download:12/0  |  Submit date:2019/01/16
Acinetobacter Baumannii  Aminoglycosides  Ksga  Translational Fidelity  Virulence