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Neuroprotective Effects of BHDPC, a Novel Neuroprotectant, on Experimental Stroke by Modulating Microglia Polarization Journal article
ACS CHEMICAL NEUROSCIENCE, 2019,Volume: 10,Issue: 5,Page: 2434-2449
Authors:  Chuwen Li;  Yaqi Bian;  Yu Feng;  Fan Tang;  Liang Wang;  Maggie Pui Man Hoi;  Dan Ma;  Chao Zhao;  Simon Ming Yuen Lee
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Bhdpc  Ischemic Stroke  Microglia  Nf-κb  Creb  Pka  
Cnidarian peptide neurotoxins: a new source of various ion channel modulators or blockers against central nervous systems disease Journal article
DRUG DISCOVERY TODAY, 2019,Volume: 24,Issue: 1,Page: 189-197
Authors:  Qiwen Liao;  Yu Feng;  Binrui Yang;  Simon Ming-Yuen Lee
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Vascular endothelial growth factor gene transfer therapy for coronary artery disease: A systematic review and meta-analysis Journal article
CARDIOVASCULAR THERAPEUTICS, 2018,Volume: 36,Issue: 5
Authors:  Yuan, Rong;  Xin, Qiqi;  Shi, Weili;  Liu, Wei;  Lee, Simon-M.;  Hoi, Puiman;  Li, Lin;  Zhao, Jun;  Cong, Weihong;  Chen, Keji
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Angina Pectoris  Angiogenesis Inducing Agents  Coronary Artery Disease  Genetic Therapy  Myocardial Ischemia  Vascular Endothelial Growth Factor  
Identification of certain Panax species to be potential substitutes for Panax notoginseng in hemostatic treatments Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 134,Page: 1-15
Authors:  Yang, Bin Rui;  Yuen, Sze Chung;  Fan, Guang Yi;  Cong, Wei-Hong;  Leung, Siu-Wai;  Lee, Simon Ming-Yuen
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Panax Notoginseng  Historical And Medical Use  Plantation  Morphology  Geographical Distribution  Nomenclature  
A novel Ca2+ current blocker promotes angiogenesis and cardiac healing after experimental myocardial infarction in mice Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 134,Page: 109-117
Authors:  Guozhen Cui;  Qiqi Xin;  Hisa Hui Ling Tseng;  Maggie PuiMan Hoi;  Yan Wang;  Binrui Yang;  InLeng Choi;  Yuqiang Wang;  Rong Yuan;  Keji Chen;  Weihong Cong;  Simon MingYuen Lee
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Cardioprotection  Angiogenesis  Adtm  Zebrafish  Vegf  
Sodium tanshinone IIA sulfonate promotes endothelial integrity via regulating VE-cadherin dynamics and RhoA/ROCK-mediated cellular contractility and prevents atorvastatin-induced intracerebral hemorrhage in zebrafish Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 350,Page: 32-42
Authors:  Zhou, Zhong-Yan;  Huang, Bin;  Li, Shang;  Huang, Xiao-Hui;  Tang, Jing-Yi;  Kwan, Yiu Wa;  Hoi, Pui Man;  Lee, Simon Ming-Yuen
Favorite  |  View/Download:27/0  |  Submit date:2018/10/30
Sodium Tanshinone Iia Sulfonate  Salvia Miltiorrhiza  Hemorrhagic Stroke  Atorvastatin  Rock  
BHDPC Is a Novel Neuroprotectant That Provides Anti-neuroinflammatory and Neuroprotective Effects by Inactivating NF-kappa B and Activating PKA/CREB Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Li, Chuwen;  Chen, Tongkai;  Zhou, Hefeng;  Feng, Yu;  Hoi, Maggie P. M.;  Ma, Dan;  Zhao, Chao;  Zheng, Ying;  Lee, Simon M. Y.
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Bhdpc  Neuroinflammation  Microglia  Nf-kappa b  Creb  Pka  
The holo-transcriptome of the zoantharian protopalythoa variabilis (cnidaria: Anthozoa): A plentiful source of enzymes for potential application in green chemistry, industrial and pharmaceutical biotechnology Journal article
Marine Drugs, 2018,Volume: 16,Issue: 6
Authors:  Morlighem J.-E.R.L.;  Huang C.;  Liao Q.;  Gomes P.B.;  Perez C.D.;  Prieto-da-Silva A.R.D.B.;  Lee S.M.-Y.;  Radis-Baptista G.
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Cnidarian Transcriptome  Holo-transcriptome  Marine Biocatalyst  Marine Biotechnology  Marine Enzyme  Pharmaceutical Biotechnology  Zoanthidea  
A novel compound DT-010 protects against doxorubicin-induced cardiotoxicity in zebrafish and H9c2 cells by inhibiting reactive oxygen species-mediated apoptotic and autophagic pathways Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 820,Page: 86-96
Authors:  Tang, Fan;  Zhou, Xinhua;  Wang, Liang;  Shan, Luchen;  Li, Chuwen;  Zhou, Hefeng;  Lee, Simon Ming-Yuen;  Hoi, Maggie Pui-Man
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Cardioprotection  Anti-oxidative Stress  Anti-apoptosis  Autophagy Regulation  Zebrafish Cardiotoxicity  H9c2 Cardiomyocytes  
Tanshinone I prevents atorvastatin-induced cerebral hemorrhage in zebrafish and stabilizes endothelial cell-cell adhesion by inhibiting. VE-cadherin internalization and actin-myosin contractility Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 128,Page: 389-398
Authors:  Huang, Bin;  Zhou, Zhong-Yan;  Li, Shang;  Huang, Xiao-Hui;  Tang, Jing-Yi;  Hoi, Maggie Pui Man;  Lee, Simon Ming Yuen
Favorite  |  View/Download:30/0  |  Submit date:2018/10/30
Tanshinone i  Vascular Integrity  Endothelial Cell Adhesion  Hemorrhagic Stroke  Zebrafish  Huvecs