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Development of a Liposomal Formulation of Acetyltanshinone IIA for Breast Cancer Therapy Journal article
MOLECULAR PHARMACEUTICS, 2019,Volume: 16,Issue: 9,Page: 3873-3886
Authors:  Qi Wang;  Man Luo;  Na We;  Alex Chang;  Kathy Qian Luo
Favorite  |  View/Download:37/0  |  Submit date:2020/05/12
Anti-breast Cancer Drugs  Acetyltanshinone Iia (Ata)  Mpeg-liposomes  Bioavailabilit  Pharmacokinetics  Toxicity Study  
An open-label randomised comparison of aripiprazole, olanzapine and risperidone for the acute treatment of first-episode schizophrenia: Eight-week outcomes Journal article
JOURNAL OF PSYCHOPHARMACOLOGY, 2019,Volume: 33,Issue: 10,Page: 1227-1236
Authors:  Zhang Cheng;  Yanbo Yuan;  Xue Han;  Shangli Cai;  Fude Yang;  Zheng Lu;  Chuanyue Wang;  Hong Deng;  Jingping Zhao;  Yutao Xiang;  Christoph U Correll;  Xin Yu
Favorite  |  View/Download:4/0  |  Submit date:2020/05/26
First-episode  Schizophrenia  Antipsychotic  Efficacy  Safety  
A Danshensu-Tetramethylpyrazine Conjugate DT-010 Overcomes Multidrug Resistance in Human Breast Cancer Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:  Xinhua Zhou;  Anqi Wang;  Liang Wang;  Jianhua Yin;  Li Wang;  Lijun Di;  Maggie Pui-Man Hoi;  Luchen Shan;  Xu Wu;  Yuqiang Wang
Favorite  |  View/Download:9/0  |  Submit date:2020/05/21
Danshensu  Tetramethylpyrazine  Breast Cancer  Resistance  Glycolysis  P-glycoprotein  
Synthesis and biological evaluation of aza-crown ether–squaramide conjugates as anion/cation symporters Journal article
FUTURE MEDICINAL CHEMISTRY, 2019,Volume: 11,Issue: 10,Page: 1091-1106
Authors:  Xi-Hui Yu;  Xiong-Jie Cai;  Xiao-Qiao Hong;  Kin Yip Tam;  Kun Zhang;  Wen-Hua Chen
Favorite  |  View/Download:14/0  |  Submit date:2020/05/21
Combined use of arginase and dichloroacetate exhibits anti-proliferative effects in triple negative breast cancer cells Journal article
JOURNAL OF PHARMACY AND PHARMACOLOGY, 2019,Volume: 71,Issue: 3,Page: 306-315
Authors:  Angela Verma;  Yau-Min Lam;  Yun-Chung Leung;  Xiaohui Hu;  Xin Chen;  Edwin Cheung;  Kin Yip Tam
Favorite  |  View/Download:16/0  |  Submit date:2020/05/21
Bacillus Caldovelox Arginase  Breast Cancer  Dichloroacetate  Drug Combination  Pegyated Human Arginase  
Trends of Polypharmacy and Prescription Patterns of Antidepressants in Asia Journal article
JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 2018,Volume: 38,Issue: 6,Page: 598-603
Authors:  Huang, Cho-Yin;  Yang, Shu-Yu;  Mojtabai, Ramin;  Lin, Shu-Ku;  He, Yan-Ling;  Chong, Mian-Yoon;  Ungvari, Gabor;  Tan, Chay-Hoon;  Xiang, Yu-Tao;  Sartorius, Norman;  Shinfuku, Naotaka;  Chen, Lian-Yu
Favorite  |  View/Download:32/0  |  Submit date:2019/01/17
Antidepressant Use  Polypharmacy  Prescription Pattern  
Identification of Novel Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors by Kinase Activity-Based High-Throughput Screening for Anticancer Therapeutics Journal article
ACS Combinatorial Science, 2018,Volume: 20,Issue: 11,Page: 660-671
Authors:  Zhang W.;  Hu X.;  Chakravarty H.;  Yang Z.;  Tam K.Y.
Favorite  |  View/Download:18/0  |  Submit date:2018/12/18
cancer  high-throughput screening  pyruvate dehydrogenase kinase 1  small molecule inhibitors  Warburg effect  
Inhibition of pyruvate dehydrogenase kinase 1 enhances the anti-cancer effect of EGFR tyrosine kinase inhibitors in non-small cell lung cancer Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 838,Page: 41-52
Authors:  Yang, Zheng;  Zhang, Shao-Lin;  Hu, Xiaohui;  Tam, Kin Yip
Favorite  |  View/Download:27/0  |  Submit date:2018/10/30
Dichloroacetophenone  Epidermal Growth Factor Receptor  Tyrosine Kinase Inhibitor  Synergism  Hypoxia  Oxidative Phosphorylation  
Editorial, IAPC-6 Meeting Journal article
PHARMACEUTICAL RESEARCH, 2018,Volume: 35,Issue: 11
Authors:  Tam, Kin;  Li, Tonglei;  Mandic, Zoran
Favorite  |  View/Download:5/0  |  Submit date:2019/01/17
Anticancer effects of some novel dichloroacetophenones through the inhibition of pyruvate dehydrogenase kinase 1 Journal article
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2018,Volume: 123,Page: 43-55
Authors:  Zhang, Shao-Lin;  Yang, Zheng;  Hu, Xiaohui;  Chakravarty, Harapriya;  Tam, Kin Yip
Favorite  |  View/Download:22/0  |  Submit date:2018/10/30
Dichloroacetophenone  Pyruvate Dehydrogenase Kinase  Pyruvate Dehydrogenase Complex  Anticancer Activity  Metabolic Reprogramming