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Dimeric bis (heptyl)-Cognitin Blocks Alzheimer's β-Amyloid Neurotoxicity Via the Inhibition of Aβ Fibrils Formation and Disaggregation of Preformed Fibrils Journal article
CNS Neuroscience and Therapeutics, 2015,Volume: 21,Issue: 12,Page: 953-961
Authors:  Hu S.-Q.;  Wang R.;  Cui W.;  Mak S.-H.;  Li G.;  Hu Y.-J.;  Lee M.-Y.;  Pang Y.-P.;  Han Y.-F.
Favorite  |  View/Download:7/0  |  Submit date:2018/11/06
Alzheimer's disease  Aβ fibrils  Bis (heptyl)-cognitin  Morris water maze  Reactive oxygen stress  Thioflavin T  
The human Nox4: gene, structure, physiological function and pathological significance Journal article
Journal of Drug Targeting, 2015,Volume: 23,Issue: 10,Page: 888-896
Authors:  Shuhui Guo;  Xiuping Chen
Favorite  |  View/Download:5/0  |  Submit date:2019/01/07
Cancer  Cardiovascular Diseases  Hydrogen Peroxides  Nox4  Ros  
Cucurbitacin B induces DNA damage and autophagy mediated by reactive oxygen species (ROS) in MCF-7 breast cancer cells Journal article
Journal of Natural Medicines, 2015,Volume: 69,Issue: 4,Page: 522-530
Authors:  Ren G.;  Sha T.;  Guo J.;  Li W.;  Lu J.;  Chen X.
Favorite  |  View/Download:8/0  |  Submit date:2018/12/28
Autophagy  Breast Cancer  Cucurbitacin b  Dna Damage  Ros  
Upregulation of angiotensin (1-7)-mediated signaling preserves endothelial function through reducing oxidative stress in diabetes Journal article
Antioxidants and Redox Signaling, 2015,Volume: 23,Issue: 11,Page: 880-892
Authors:  Zhang Y.;  Liu J.;  Luo J.-Y.;  Tian X.Y.;  Cheang W.S.;  Xu J.;  Lau C.W.;  Wang L.;  Wong W.T.;  Wong C.M.;  Lan H.Y.;  Yao X.;  Raizada M.K.;  Huang Y.
Favorite  |  View/Download:5/0  |  Submit date:2019/01/15
Chemically bonding of amantadine with gardenamide A enhances the neuroprotective effects against corticosterone-induced insults in PC12 cells Journal article
International Journal of Molecular Sciences, 2015,Volume: 16,Issue: 9,Page: 22795-22810
Authors:  Zhao J.;  Peng L.;  Zheng W.;  Wang R.;  Zhang L.;  Yang J.;  Chen H.
Favorite  |  View/Download:4/0  |  Submit date:2018/12/21
Amantadine  eNOS  Gardenamide A  Neuroprotection  NMDA  nNOS  
Gardenamide a protects RGC-5 cells from H2O2-induced oxidative stress insults by activating PI3K/Akt/eNOS signaling pathway Journal article
International Journal of Molecular Sciences, 2015,Volume: 16,Issue: 9,Page: 22350-22367
Authors:  Wang R.;  Peng L.;  Zhao J.;  Zhang L.;  Guo C.;  Zheng W.;  Chen H.
Favorite  |  View/Download:3/0  |  Submit date:2018/12/21
Cell apoptosis  Gardenamide A  Neuroprotection  Neurotoxicity  Oxidative stress  
UPLC/Q-TOFMS-Based Metabolomics Studies on the Protective Effect of Panax notoginseng Saponins on Alcoholic Liver Injury Journal article
American Journal of Chinese Medicine, 2015,Volume: 43,Issue: 4,Page: 695-714
Authors:  Liu F.;  Bai X.;  Ding R.-B.;  Hu Y.-J.;  Su H.;  Wan J.-B.
Favorite  |  View/Download:7/0  |  Submit date:2018/12/28
Chronic Alcohol-induced Liver Injury  Metabolomics  Panax Notoginseng Saponins  Uplc/q-tofms  
Total tanshinones-induced apoptosis and autophagy via reactive oxygen species in lung cancer 95D Cells Journal article
American Journal of Chinese Medicine, 2015,Volume: 43,Issue: 6,Page: 1265-1279
Authors:  Gao H.;  Sun W.;  Zhao W.;  Hao W.;  Leung C.-H.;  Lu J.;  Chen X.
Favorite  |  View/Download:6/0  |  Submit date:2018/11/06
Apoptosis  Autophagy  Reactive Oxygen Species  Total Tanshinones  
Schisantherin A protects against 6-OHDA-induced dopaminergic neuron damage in zebrafish and cytotoxicity in SH-SY5Y cells through the ROS/NO and AKT/GSK3 β pathways Journal article
JOURNAL OF ETHNOPHARMACOLOGY, 2015,Volume: 170,Page: 8-15
Authors:  Lun Qing Zhang;  Fei Sa;  Cheong Meng Chong;  Ying Wang;  Zhong Yan Zhou;  Raymond Chuen Chung Chang;  Shun Wan Chan;  Pui Man Hoi;  Simon Ming Yuen Lee
Favorite  |  View/Download:3/0  |  Submit date:2020/04/15
6-hydroxydopamine (6-ohda)  Oxidative Stress  Parkinson׳s Disease  Schisantherin a  
Black tea protects against hypertension-associated endothelial dysfunction through alleviation of endoplasmic reticulum stress Journal article
Scientific Reports, 2015,Volume: 5
Authors:  Cheang W.S.;  Ngai C.Y.;  Tam Y.Y.;  Tian X.Y.;  Wong W.T.;  Zhang Y.;  Lau C.W.;  Chen Z.Y.;  Bian Z.-X.;  Huang Y.;  Leung F.P.
Favorite  |  View/Download:7/0  |  Submit date:2019/01/15