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Therapeutic Potential of Pien-Tze-Huang: A Review on Its Chemical Composition, Pharmacology, and Clinical Application Journal article
Molecules, 2019,Volume: 24,Issue: 18
Authors:  Lili Huang;  Yiping Zhang;  Xiaoqin Zhang;  Xiuping Chen;  Yitao Wang;  Jinjian Lu;  Mingqing Huang
Favorite  |  View/Download:12/0  |  Submit date:2020/03/27
Pien-tze-huang  Chemical Composition  Pharmacology  Clinical Application  Cancer  
Platycodin D triggers the extracellular release of programed death Ligand-1 in lung cancer cells Journal article
FOOD AND CHEMICAL TOXICOLOGY, 2019,Volume: 131
Authors:  Mu-Yang Huang;  Xiao-Ming Jiang;  Yu-Lian Xu;  Luo-Wei Yuan;  Yu-Chi Chen;  Guozhen Cui;  Run-Yue Huang;  Bo Liu;  Yitao Wang;  Xiuping Chen;  Jin-Jian Lu
Favorite  |  View/Download:18/0  |  Submit date:2019/11/22
Programmed Death Ligand-1  Platycodin d  Extracellular Release  Natural Products  Cancer  
Nagilactone E suppresses TGF-beta 1-induced epithelial-mesenchymal transition, migration and invasion in non-small cell lung cancer cells Journal article
PHYTOMEDICINE, 2019,Volume: 52,Page: 32-39
Authors:  Le-Le Zhang;  Xiao-Ming Jiang;  Mu-Yang Huang;  Zhe-Ling Feng;  Xiuping Chen;  Yitao Wang;  Hua Li;  Ao Li;  Li-Gen Lin;  Jin-Jian Lu
Favorite  |  View/Download:19/0  |  Submit date:2020/01/09
Nagilactone e  Tgf-β1  Epithelial-mesenchymal Transitio  Smad  
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
View  |  Adobe PDF(2621Kb)  |  Favorite  |  View/Download:814/37  |  Submit date:2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
View  |  Adobe PDF(3226Kb)  |  Favorite  |  View/Download:559/32  |  Submit date:2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Diethyl blechnic, a novel natural product isolated from salvia miltiorrhiza bunge, inhibits doxorubicin-induced apoptosis by inhibiting ROS and activating JNK1/2 Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 6
Authors:  Yu J.;  Gao H.;  Wu C.;  Xu Q.-M.;  Lu J.-J.;  Chen X.
Favorite  |  View/Download:8/0  |  Submit date:2018/12/28
Cardiotoxicity  Diethyl Blechnic  Dox  Jnk1/2  Ros  
Novel biflavonoids from Cephalotaxus oliveri Mast Journal article
PHYTOCHEMISTRY LETTERS, 2018,Volume: 24,Page: 150-153
Authors:  Ren, Dai;  Meng, Fan-Cheng;  Liu, Hui;  Xiao, Tong;  Lu, Jin-Jian;  Lin, Li-Gen;  Chen, Xiu-Ping;  Zhang, Qing-Wen
Favorite  |  View/Download:32/0  |  Submit date:2018/10/30
Cephalotaxus Oliveri  Biflavonoid  Flavonoid  Alkaloid  Umcephabiflovin  Alpha-glucosidase Inhibitory Effect  
Recent progress in doxorubicin-induced cardiotoxicity and protective potential of natural products Journal article
PHYTOMEDICINE, 2018,Volume: 40,Page: 125-139
Authors:  Yu, Jie;  Wang, Changxi;  Kong, Qi;  Wu, Xiaxia;  Lu, Jin-Jian;  Chen, Xiuping
Favorite  |  View/Download:17/0  |  Submit date:2018/10/30
Doxorubicin  Cardiotoxicity  Natural Products  
Increased expression of IRE1α associates with the resistant mechanism of osimertinib (AZD9291)-resistant non-small cell lung cancer HCC827/OSIR cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2018,Volume: 18,Issue: 4,Page: 550-555
Authors:  Tang Z.-H.;  Su M.-X.;  Guo X.;  Jiang X.-M.;  Jia L.;  Chen X.;  Lu J.-J.
Favorite  |  View/Download:8/0  |  Submit date:2018/12/28
Azd9291  Egfr  Ire1α  Lune Cancer  Nsclc  Osimertinib  
2-methoxy-6-acetyl-7-methyljuglone (MAM) induces iNOS/NO-mediated DNA damage response through activation of MAPKs pathways Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2018,Volume: 18,Issue: 6,Page: 903-913
Authors:  Niu Y.;  Yuan R.;  Gao H.;  Lu J.-J.;  Kong Q.;  Chen X.
Favorite  |  View/Download:9/0  |  Submit date:2018/12/28
Atm/chk2  Dna Damage  Inos/no  L-arginine  Mam  Mapks