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NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Miao,Kai;  Lei,Josh Haipeng;  Valecha,Monica Vishnu;  Zhang,Aiping;  Xu,Jun;  Wang,Lijian;  Lyu,Xueying;  Chen,Si;  Miao,Zhengqiang;  Zhang,Xin;  Su,Sek Man;  Shao,Fangyuan;  Rajendran,Barani Kumar;  Bao,Jiaolin;  Zeng,Jianming;  Sun,Heng;  Chen,Ping;  Tan,Kaeling;  Chen,Qiang;  Wong,Koon Ho;  Xu,Xiaoling;  Deng,Chu Xia
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Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Sun,Xianding;  Zhou,Yang;  Zhang,Ruobin;  Wang,Zuqiang;  Xu,Meng;  Zhang,Dali;  Huang,Junlan;  Luo,Fengtao;  Li,Fangfang;  Ni,Zhenhong;  Zhou,Siru;  Chen,Hangang;  Chen,Shuai;  Chen,Liang;  Du,Xiaolan;  Chen,Bo;  Huang,Haiyang;  Liu,Peng;  Yin,Liangjun;  Qiu,Juhui;  Chen,Di;  Deng,Chuxia;  Xie,Yangli;  Luo,Lingfei;  Chen,Lin
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A digital microfluidic system with 3D microstructures for single-cell culture Journal article
Microsystems and Nanoengineering, 2020,Volume: 6,Issue: 1
Authors:  Zhai,Jiao;  Li,Haoran;  Wong,Ada Hang Heng;  Dong,Cheng;  Yi,Shuhong;  Jia,Yanwei;  Mak,Pui In;  Deng,Chu Xia;  Martins,Rui P.
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Low-toxicity FePt nanoparticles for the targeted and enhanced diagnosis of breast tumors using few centimeters deep whole-body photoacoustic imaging Journal article
Photoacoustics, 2020,Volume: 19
Authors:  Liu,Yubin;  Wu,Pei Chun;  Guo,Sen;  Chou,Pi Tai;  Deng,Chuxia;  Chou,Shang Wei;  Yuan,Zhen;  Liu,Tzu Ming
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Breast cancer  FePt nanoparticles  Imaging depth  Whole-body photoacoustic imaging  
Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells Journal article
Acta Pharmaceutica Sinica B, 2020,Volume: 10,Issue: 4,Page: 615-627
Authors:  Zhang,Baoyuan;  Lyu,Junfang;  Yang,Eun Ju;  Liu,Yifan;  Wu,Changjie;  Pardeshi,Lakhansing;  Tan,Kaeling;  Chen,Qiang;  Xu,Xiaoling;  Deng,Chu Xia;  Shim,Joong Sup
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BRCA1  Breast cancer  DNA damage  HDAC  Histone deacetylase  Reactive oxygen species  Synthetic lethality  
PRDM3 attenuates pancreatitis and pancreatic tumorigenesis by regulating inflammatory response Journal article
Cell Death and Disease, 2020,Volume: 11,Issue: 3
Authors:  Ye,Jie;  Huang,Anpei;  Wang,Haitao;  Zhang,Anni M.Y.;  Huang,Xiaojun;  Lan,Qingping;  Sato,Tomohiko;  Goyama,Susumu;  Kurokawa,Mineo;  Deng,Chuxia;  Sander,Maike;  Schaeffer,David F.;  Li,Wen;  Kopp,Janel L.;  Xie,Ruiyu
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BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis Journal article
Advanced Science, 2020,Volume: 7,Issue: 6
Authors:  Chen,Qiang;  Lei,Josh Haipeng;  Bao,Jiaolin;  Wang,Haitao;  Hao,Wenhui;  Li,Licen;  Peng,Cheng;  Masuda,Takaaki;  Miao,Kai;  Xu,Jun;  Xu,Xiaoling;  Deng,Chu Xia
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ATM-AMPK-DRP1  BRCA1  inflammasomes  mitochondrial dynamics  mitophagy  
FGFR3 deficiency enhances CXCL12-dependent chemotaxis of macrophages via upregulating CXCR7 and aggravates joint destruction in mice Journal article
Annals of the Rheumatic Diseases, 2020,Volume: 79,Issue: 1,Page: 112-122
Authors:  Kuang,Liang;  Wu,Jiangyi;  Su,Nan;  Qi,Huabing;  Chen,Hangang;  Zhou,Siru;  Xiong,Yan;  Du,Xiaolan;  Tan,Qiaoyan;  Yang,Jing;  Jin,Min;  Luo,Fengtao;  Ouyang,Junjie;  Zhang,Bin;  Wang,Zuqiang;  Jiang,Wanling;  Chen,Liang;  Chen,Shuai;  Wang,Ziming;  Liu,Peng;  Yin,Liangjun;  Guo,Fengjin;  Deng,Chuxia;  Chen,Di;  Liu,Chuanju;  Xie,Yangli;  Ni,Zhenhong;  Chen,Lin
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arthritis  chemokines  inflammation  synovitis  
Imaging of macrophage mitochondria dynamics in vivo reveals cellular activation phenotype for diagnosis Journal article
Theranostics, 2020,Volume: 10,Issue: 7,Page: 2897-2917
Authors:  Li,Yue;  He,Yuan;  Miao,Kai;  Zheng,Ying;  Deng,Chuxia;  Liu,Tzu Ming
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In vivo imaging  Liposome  Macrophage  Mitochondria  Multiphoton microscopy  
Stagewise keratinocyte differentiation from human embryonic stem cells by defined signal transduction modulators Journal article
International Journal of Biological Sciences, 2020,Volume: 16,Issue: 8,Page: 1450-1462
Authors:  Zhong,Hui;  Ren,Zhili;  Wang,Xiaoyan;  Miao,Kai;  Ni,Wenjun;  Meng,Ya;  Lu,Ligong;  Wang,Chunming;  Liu,Weiwei;  Deng,Chu Xia;  Xu,Ren He;  Chen,Guokai
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Defined factors  Human embryonic stem cells  Keratinocyte differentiation