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MLKL mediates apoptosis via a mutual regulation with PERK/eIF2α pathway in response to reactive oxygen species generation Journal article
Apoptosis, 2018,Volume: 23,Issue: 9-10,Page: 521-531
Authors:  Cao W.-X.;  Li T.;  Tang Z.-H.;  Zhang L.-L.;  Wang Z.-Y.;  Guo X.;  Su M.-X.;  Chen X.;  Lu J.-J.
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Apoptosis  Chelerythrine  Eif2α  Mlkl  Ros  
Increased expression of IRE1α associates with the resistant mechanism of osimertinib (AZD9291)-resistant non-small cell lung cancer HCC827/OSIR cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2018,Volume: 18,Issue: 4,Page: 550-555
Authors:  Tang Z.-H.;  Su M.-X.;  Guo X.;  Jiang X.-M.;  Jia L.;  Chen X.;  Lu J.-J.
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Azd9291  Egfr  Ire1α  Lune Cancer  Nsclc  Osimertinib  
Identification of a novel autophagic inhibitor cepharanthine to enhance the anti-cancer property of dacomitinib in non-small cell lung cancer Journal article
CANCER LETTERS, 2018,Volume: 412,Page: 1-9
Authors:  Tang, Zheng-Hai;  Cao, Wen-Xiang;  Guo, Xia;  Dai, Xiao-Yang;  Lu, Jia-Hong;  Chen, Xiuping;  Zhu, Hong;  Lu, Jin-Jian
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Cepharanthine  Autophagy  Lysosome  Dacomitinib  Nsclc  
Synergistic effects of Chuanxiong-Chishao herb-pair on promoting angiogenesis at network pharmacological and pharmacodynamic levels Journal article
CHINESE JOURNAL OF INTEGRATIVE MEDICINE, 2017,Volume: 23,Issue: 9,Page: 654-662
Authors:  Wang Yan;  Guo Gang;  Yang Bin-rui;  Xin Qi-qi;  Liao Qi-wen;  Lee Simon Ming-Yuen;  Hu Yuan-jia;  Chen Ke-jj;  Cong Wei-hong
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Tetramethylpyrazine  Paeoniflorin  Angiogenesis  Network Pharmacology  
Solasodine Induces Apoptosis, Affects Autophagy, and Attenuates Metastasis in Ovarian Cancer Cells Journal article
PLANTA MEDICA, 2017,Volume: 83,Issue: 3-4,Page: 254-260
Authors:  Xu, Xiao-Huang;  Zhang, Le-Le;  Wu, Guo-Sheng;  Chen, Xin;  Li, Ting;  Chen, Xiuping;  Wang, Yi-Tao;  Lu, Jin-Jian
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Ovarian Cancer  Solasodine  Apoptosis  Autophagy  Migration  Invasion  
Chemical constituents and biological research on plants in the genus Curcuma Journal article
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, 2017,Volume: 57,Issue: 7,Page: 1451-1523
Authors:  Sun, Wen;  Wang, Sheng;  Zhao, Wenwen;  Wu, Chuanhong;  Guo, Shuhui;  Gao, Hongwei;  Tao, Hongxun;  Lu, Jinjian;  Wang, Yitao;  Chen, Xiuping
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Genus Curcuma  Chemical Constituents  Bioactivities  Antitumor  
Fangchinoline accumulates autophagosomes by inhibiting autophagic degradation and promoting TFEB nuclear translocation Journal article
RSC ADVANCES, 2017,Volume: 7,Issue: 67,Page: 42597-42605
Authors:  Tang, Zheng-Hai;  Guo, Xia;  Cao, Wen-Xiang;  Chen, Xiuping;  Lu, Jin-Jian
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Characterization of osimertinib (AZD9291)-resistant non-small cell lung cancer NCI-H1975/OSIR cell line Journal article
Oncotarget, 2016,Volume: 7,Issue: 49,Page: 81598-81610
Authors:  Tang Z.-H.;  Jiang X.-M.;  Guo X.;  Fong C.M.V.;  Chen X.;  Lu J.-J.
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Azd9291  Egfr  Navitoclax  Nsclc  Osimertinib  
Isocryptotanshinone, a STAT3 inhibitor, induces apoptosis and pro-death autophagy in A549 lung cancer cells Journal article
Journal of Drug Targeting, 2016,Volume: 24,Issue: 10,Page: 934-942
Authors:  Shuhui Guo;  Weiwei Luo;  Lijuan Liu;  Xiaocong Pang;  Hong Zhu;  Ailin Liu;  Jinjian Lu;  Dik-Lung Ma;  Chung-Hang Leung;  Yitao Wang;  Xiuping Chen
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Apoptosis  Autophagy  Isocryptotanshinone  Stat3  
Cucurbitacin B induces DNA damage and autophagy mediated by reactive oxygen species (ROS) in MCF-7 breast cancer cells Journal article
Journal of Natural Medicines, 2015,Volume: 69,Issue: 4,Page: 522-530
Authors:  Ren G.;  Sha T.;  Guo J.;  Li W.;  Lu J.;  Chen X.
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Autophagy  Breast Cancer  Cucurbitacin b  Dna Damage  Ros