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Characterization of the Molecular Mechanisms Underlying the Chronic Phase of Stroke in a Cynomolgus Monkey Model of Induced Cerebral Ischemia Journal article
JOURNAL OF PROTEOME RESEARCH, 2017,Volume: 16,Issue: 3,Page: 1150-1166
Authors:  Law, Henry C. H.;  Szeto, Samuel S. W.;  Quan, Quan;  Zhao, Yun;  Zhang, Zaijun;  Krakovska, Olga;  Lui, Leong Ting;  Zheng, Chengyou;  Lee, Simon M. -Y.;  Siu, K. W. Michael;  Wang, Yuqiang;  Chu, Ivan K.
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Stroke Biology  Itraq  Cynomolgus Monkey  Brain Proteome  Ischemia  Chronic Phase  
Tetramethylpyrazine nitrone, a multifunctional neuroprotective agent for ischemic stroke therapy Journal article
Scientific Reports, 2016,Volume: 6
Authors:  Zaijun Zhang;  Gaoxiao Zhang;  Yewei Sun;  Samuel S. W. Szeto;  Henry C. H. Law;  Quan Quan;  Guohui Li;  Pei Yu;  Eiketsu Sho;  Michael K. W. Siu;  Simon M. Y. Lee;  Ivan K. Chu;  Yuqiang Wang
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Discovery, synthesis, and functional characterization of a novel neuroprotective natural product from the fruit of alpinia oxyphylla for use in Parkinson's disease through LC/MS-based multivariate data analysis-guided fractionation Journal article
Journal of Proteome Research, 2016,Volume: 15,Issue: 8,Page: 2595-2606
Authors:  Guohui Li;  Zaijun Zhang;  Quan Quan;  Renwang Jiang;  Samuel S.W. Szeto;  Shuai Yuan;  Wing-tak Wong;  Herman H. C. Lam;  Simon Ming-Yuen Lee;  Ivan K. Chu
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Natural Products  Neuroprotective  Nrf2  Parkinson's Disease  Proteomics  
A versatile reversed phase-strong cation exchange-reversed phase (RP-SCX-RP) multidimensional liquid chromatography platform for qualitative and quantitative shotgun proteomics Journal article
Analyst, 2015,Volume: 140,Issue: 4,Page: 1237-1252
Authors:  Henry C. H. Law;  Ricky P. W. Kong;  Samuel S. W. Szeto;  Yun Zhao;  Zaijun Zhang;  Yuqiang Wang;  Guohui Li;  Quan Quan;  Simon M. Y. Lee;  Herman C. Lama;  Ivan K. Chu
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Examining the neuroprotective effects of protocatechuic acid and chrysin on in vitro and in vivo models of Parkinson disease Journal article
Free Radical Biology and Medicine, 2015,Volume: 84,Page: 331
Authors:  Zaijun Zhang;  Guohui Li;  Samuel S.W. Szeto;  Cheong Meng Chong;  Quan Quan;  Chen Huang;  Wei Cui;  Baojian Guo;  Yuqiang Wang;  Yifan Han;  K.W. Michael Siu;  Simon Ming Yuen Lee;  Ivan K. Chu
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Anti-inflammation  Freeradicals  Neuroprotection  Nrf2 Nf-κb  Parkinsondisease  Proteomics  
Fully automatable two-dimensional hydrophilic interaction liquid chromatography-reversed phase liquid chromatography with online tandem mass spectrometry for shotgun proteomics Journal article
Journal of Separation Science, 2012,Volume: 35,Issue: 14,Page: 1755
Authors:  Yun Zhao;  Ricky P. W. Kong;  Guohui Li;  Maggie P. Y. Lam;  C. H. Law;  Simon M. Y. Lee;  Herman C. Lam;  Ivan K. Chu
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Hilic-rp  Orthogonality  Proteomics  Two-dimensional Liquid Chromatography  
Ethanolic extract of fructus alpinia oxyphylla protects against 6-hydroxydopamine-induced damage of PC12 cells in vitro and dopaminergic neurons in zebrafish Journal article
Cellular and Molecular Neurobiology, 2012,Volume: 32,Issue: 1,Page: 27
Authors:  Zai-Jun Zhang;  Lorita C. V. Cheang;  Mei-Wei Wang;  Guo-Hui Li;  Ivan K. Chu;  Zhi-Xiu Lin;  Simon M. Y. Lee
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Fructus Alpinia Oxyphylla  Neuroprotection  Parkinson's Disease  Pc12 Cell  Zebrafish